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NCT ID: NCT05729828 Completed - Nurse's Role Clinical Trials

Psychometric Properties of the SMART Feeding Tool

Start date: May 5, 2021
Phase:
Study type: Observational

This observational study aims to evaluate the psychometric properties of a new infant feeding tool called "SMART Tool" in the neonatal intensive care unit. The main questions it aims to answer are: 1. To design a feeding tool to assess oral motor and neurobehavioral skills in neonates 2. To establish psychometrics of the new tool by doing reliability and validity tests.

NCT ID: NCT05729594 Completed - Healthy Volunteers Clinical Trials

Systemic Pharmacokinetic Study of T4032 (Unpreserved Bimatoprost 0.01%) Eye Gel Versus Lumigan® 0.01% Eye Drops in 40 Healthy Volunteers

Start date: February 27, 2023
Phase: Phase 1
Study type: Interventional

This study is being performed to compare the systemic pharmacokinetic profiles of T4032 and Lumigan 0.01% given that T4032 has a different formulation (in terms of excipients) from the reference product.

NCT ID: NCT05728944 Completed - Presbyopia Clinical Trials

Phase 3 Efficacy Study of LNZ101 for the Treatment of Presbyopia

CLARITY
Start date: April 24, 2023
Phase: Phase 3
Study type: Interventional

Phase 3 Efficacy Study to evaluate the Safety and Efficacy of LNZ101 for the Treatment of Presbyopia

NCT ID: NCT05727800 Completed - Clinical trials for Alpha-1 Antitrypsin Deficiency

A Phase 1, First-in-human Study of VX-668

Start date: February 8, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of VX-668 at various doses.

NCT ID: NCT05727514 Completed - Clinical trials for Problems Related to Life-Management Difficulty

Beyond COVID-19: Supporting Resilience With a Trauma-informed Music Composition Program

Start date: April 22, 2021
Phase: N/A
Study type: Interventional

This study explores the feasibility and acceptability of a music composition intervention to support resilience in survivors of serious illness hospitalized during the COVID-19 pandemic.

NCT ID: NCT05727202 Completed - Clinical trials for SARS-CoV-2 Infection

Project STARFISH - PRJ0002679

STARFISH
Start date: February 20, 2023
Phase:
Study type: Observational

This is a non-interventional study to perform the clinical performance evaluation of the Starfish Test using prospectively collected matched nasopharyngeal and nasal swab samples from the same donor.

NCT ID: NCT05727072 Completed - Healthy Clinical Trials

A Study of LY3848575 in Healthy Participants

Start date: February 10, 2023
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to evaluate the safety and tolerability of LY3848575 when administered either intravenously or subcutaneously in single ascending or multiple doses in healthy non-Japanese and first generation Japanese participants. The study will also assess how fast LY3848575 gets into the blood stream and how long it takes the body to remove it. The study is open to healthy participants. The study will last up to approximately 142 days excluding the screening period of 28 days.

NCT ID: NCT05726851 Completed - Healthy Volunteers Clinical Trials

A Study to Assess the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of E2025 in Healthy Participants

Start date: February 6, 2023
Phase: Phase 1
Study type: Interventional

The primary purpose of the study is to evaluate the safety and tolerability of single intravenous (IV) infusions of E2025 in healthy adult participants.

NCT ID: NCT05726448 Completed - Breast Feeding Clinical Trials

Evaluating Telehealth Solutions in WIC: Wisconsin WIC Clients

Start date: January 12, 2022
Phase: N/A
Study type: Interventional

With funding through the United States Department of Agriculture (USDA) and Tufts University's Telehealth Intervention Strategies for WIC (THIS-WIC) project, Wisconsin's (WI) WIC department will be implementing a new, customized, mobile-friendly nutrition education platform called ONE (Online Nutrition Education) in WI's WIC program. The purpose of this study is to evaluate the impact of the ONE platform. The evaluation will focus on WIC clients as the study population. The Wisconsin WIC department would be implementing this education platform, regardless of the evaluation research. The Wisconsin WIC department is responsible for implementing this new intervention, while the Tufts University research team is responsible for the evaluation of this platform through surveys and analysis of administrative data. An online survey will be used to gauge WIC clients' satisfaction with ONE, and the impact of the telehealth solution compared to usual care on breastfeed duration, dietary intake, attendance at scheduled appointments, attitudes to breastfeeding and nutrition education, and barriers encountered. Survey data will be combined with previously collected data on clients and their families from the WI Management Information Systems (MIS), and aggregate level data from the ONE telehealth solution about ONE utilization.

NCT ID: NCT05726253 Completed - Pneumonia Clinical Trials

Supportive Treatment and Antibiotics for Mild Pediatric Pneumonia

STAMPP
Start date: January 9, 2023
Phase: Early Phase 1
Study type: Interventional

National guidelines make two recommendations for treatment of young children with mild pneumonia - one to avoid routine antibiotics and another to use narrow-spectrum antibiotics. No studies have compared the effectiveness of these two approaches. This pilot study will evaluate study processes and feasibility of a future clinical trial that proposes to test whether low-risk children managed as outpatients with mild community-acquired pneumonia (CAP) treated with supportive treatment without antibiotics will have a similar clinical response, with fewer adverse effects, compared with those treated with a supportive treatment plan that includes antibiotics.