There are about 15072 clinical studies being (or have been) conducted in Turkey. The country of the clinical trial is determined by the location of where the clinical research is being studied. Most studies are often held in multiple locations & countries.
The investigators aimed to accurately measure muscle mass and predict pCR to NAC and its effect on clinical outcomes.
In this study, the investigators aim to evaluate the relationship between cecal intubation time during colonoscopies and factors such as the patient's age, body mass index, history of constipation, Wexner constipation score, antidepressant use, and previous abdominal surgery. The objective is to assess factors that may predict longer cecal intubation times, especially in difficult colonoscopies. Prior to the procedure, informed consent will be obtained from patients scheduled for colonoscopy in the surgical endoscopy unit, and relevant information will be recorded. During the procedure, data will be collected, including cecal intubation time, if ileal intubation is performed, and the total procedure time.
The aim of our study is to examine the effects of balance exercises performed in virtual and real environments on visual-spatial attention and mental rotation in healthy young adult individuals using EEG brain oscillations.
Evaluation of the Efficiency of Propioceptive Study According to Radiological Stages in Patients with Knee Osteoarthritis
Important psychological problems can be experienced after sports injuries such as anterior cruciate ligament (ACL), these delay physical recovery, affect the quality of rehabilitation and eventually cause problems or re-injuries in the process of returning to sports. The most important of these problems are re-injury anxiety, rehabilitation adherence, rehabilitation self-efficacy problems and kinesiophobia. Although some interventions have been proposed for the solution of these problems, a structured intervention approach has not been put forward yet. With this research project, our aim is to examine the effectiveness of the Cognitive Behavioral Therapy (CBT) protocol (CBT+VR) enriched with the contribution of virtual reality (VR). The research will be conducted with 60 athletes who meet the inclusion criteria. In the study, which is planned as a 4X5 (groupXmeasurement) mixed factorial design model with four groups (intervention1-intervention2-intervention3, control), the athletes will be filled with psychological assessment scales in order to collect the first data within the first week of starting physical therapy after ACL operation. The data obtained will be analyzed with multi-level statistics. Whether the anxiety levels of the athletes increase in the VR environment will be monitored with the biofeedback system, which will provide concrete data as well as subjective scales.
This study is researching an experimental drug called odronextamab, referred to as study drug. The study is focused on patients who have one of two types of cancer: follicular lymphoma (FL) or marginal zone lymphoma (MZL) that has come back after treatment (called "relapsed"), or did not respond to treatment (called "refractory"). FL and MZL are subtypes of Non-Hodgkin 's lymphoma (NHL). This study will be made up of two parts (Part 1 not randomized, Part 2 randomized - controlled). The aim of Part 1 of the study is to see how safe and tolerable the study drug is when used in combination with lenalidomide, in participants with FL or MZL, and to determine the dose of the study drug to be used in Part 2 of this study. This combination is considered "first-in-human" as it has not been tested as a combination treatment in humans before. The aim of Part 2, of the study is to assess how the combination of odronextamab and lenalidomide works compared to the combination of rituximab and lenalidomide, (the current standard-of-care treatment for FL and/or MZL). Standard-of-care means the usual medication expected and used when receiving treatment for a condition. The study is looking at several other research questions, including: - What side effects may happen from taking the study drug in combination with lenalidomide - How much study drug is in your blood at different times - Whether the body makes antibodies against the study drug (which could make the study drug less effective or could lead to side effects) - The impact from the study drug on your quality-of-life and ability to complete routine daily activities
Technologically advanced tool solutions (i.e., the highest level of automation) may not always be the preferred choice for participants when given an option. Various experiments show that in vehicles, low to moderate levels of automation are often preferred over highly automated vehicles. The association of higher task demands with smarter tools has been reported to influence tool selection along with task demand. However, participants may avoid using a fully automatic tool even if the task is highly laborious. In fact, in a series of experiments, participants more distinctly preferred manually completing routine tasks over more efficient fully automatic task completion. Based on these collective theories, the Smart Tools Proneness Questionnaire (STP-Q), developed by Navarro J. and colleagues, aims to explore and measure interindividual differences influencing an individual's propensity to use smart tools, their initial selection of smart tools, and subsequent usage. In practice, measuring the propensity of any individual to use smart tools will be significantly beneficial for both professionals and non-professionals involved in designing, producing, and implementing such tools. Therefore, the purpose of this study is to translate, validate, and establish the reliability of the Turkish version of the STP-Q.
The aim of this study is to determine the effect of preoperative preparation applied with an interactive robot on children's preoperative anxiety and fear levels. Hypothesis; H1: Pre-operative preparation with an interactive robot has an effect on the anxiety level of children H2: Pre-operative preparation with an interactive robot has an effect on the fear level of children H3: The anxiety levels of children in intervention and control groups are different after the pre-operative preparation H4: The fear levels of children in intervention and control groups are different after the pre-operative preparation
The primary aim of this study was to investigate the effects of progressive neck motor control exercises on craniocervical pain, posture, function and kinesiophobia in different types of temporomandibular dysfunction. The secondary aim of the study was to examine the differences between the effects of progressive neck motor control exercises on different types of temporomandibular dysfunction.
The aim of this study is to evaluate the effect of digital storytelling intervention on diabetes self-management in women with gestational diabetes. It is a quasi-experimental study with a pretest-posttest control group. The main hypotheses of the study are: Digital storytelling has an impact on women with gestational diabetes' perception of diabetes self-management. Digital storytelling has an impact on the diabetes self-efficacy levels of women with gestational diabetes.