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NCT ID: NCT05825989 Recruiting - Aging Clinical Trials

The Effects of Healthy Beat Acupunch on Physical Fitness of Thai Older Adults in Residential Homes

Start date: June 7, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to test the effects of the first three months of instructor-led HBA regimen on physical fitness (aerobic endurance, lung capacity, upper body flexibility, lower body flexibility, handgrip strength, upper body strength, and lower body strength) between the HBA intervention and control groups, to test the effects of another three months of DVD-led HBA regimen followed by the three months of instructor-led on physical fitness between the HBA intervention and control groups and to test the changes at three and six months of the HBA regimen in comparison to the baseline of the physical fitness in the HBA intervention group.

NCT ID: NCT05818826 Recruiting - Septic Shock Clinical Trials

Early Versus Conventional Cessation of Hydrocortisone in Septic Shock

CESSHYDRO
Start date: July 5, 2023
Phase: Phase 2
Study type: Interventional

Septic shock is one of the causes of death in ICU and hospital. Refractory shock is the problem which healthcare providers should recognize though it is difficult to handle with. The corticosteroid called hydrocortisone is one of the treatment in refractory septic shock which requires vasopressor to maintain blood pressure. In recovery phase of septic shock and weaning off vasopressor, there is no definite way to taper off hydrocortisone.

NCT ID: NCT05813964 Recruiting - HIV/AIDS Clinical Trials

Efficacy, Acceptability and Safety of Event-driven HIV PrEP Using TAF/FTC in MSM in Thailand and France.

SimpPrEP
Start date: June 5, 2024
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy, acceptability, and safety of a simplified event-driven pre-exposure prophylaxis of HIV based on oral TAF/FTC in HIV-uninfected cisgender men who have sex with men (MSM). Primary objective: To assess the efficacy of emtricitabine 200 mg + tenofovir alafenamide 25 mg (F/TAF), taken 2 to 24 hours before sexual intercourse followed by a second dose 24 hours after the first intake, in reducing the risk of HIV acquisition in MSM relative to the background HIV incidence rate.

NCT ID: NCT05813912 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

A Research Study to See How a New Weekly Insulin, Insulin Icodec When Given Along With Semaglutide Helps in Reducing the Blood Sugar Level in Patients With Type 2 Diabetes

Start date: September 22, 2023
Phase: Phase 3
Study type: Interventional

This study looks at how a new medicine insulin icodec helps in reducing blood sugar levels when given along with semaglutide in patients with type 2 diabetes. Participants will get the medicine insulin icodec once a week in the first part of the study (run-in period-26 weeks). Participants will only enter the second part of the study if the blood sugar levels have not reduced to normal. If blood sugar levels are normal after the first 26 weeks, participants will continue in a 5-week follow up period. In the second part of the study (intensification period-26 weeks), participants will get both insulin icodec and semaglutide once weekly after which they will continue in a 5-week follow up period. Participants will have to inject the study medicines once a week on the same day of the week in a skin fold in the thigh, upper arm or stomach. The study will last for about 13 months. Participants will get a blood glucose meter to check blood sugar levels. In addition, participants will be asked to enter blood sugar levels in the study phone. In addition, Participants will be asked to enter selected few blood sugar values (three times during the study) in a paper diary that will be provided to participants. Women cannot take part if pregnant, breast-feeding or plan to get pregnant during the study period.

NCT ID: NCT05813119 Completed - Diagnosis Clinical Trials

Efficacy of Digital Otoscope and Otoendoscope for Diagnosis of Middle Ear Pathology

otoscopy
Start date: July 1, 2022
Phase:
Study type: Observational

For diagnosis of external and middle ear diseases, an otoscope is a key instrument to use. A microscope has been used as a reference standard to confirm pathology. An endoscope has been also widely used. Both microscope and endoscope provide an excellent image quality, can record and capture the images, and the images can be visualized with an export system. A digital otoscope is widely available and more affordable. A comparative study of the efficacy of the endoscope and the digital endoscope will be performed.

NCT ID: NCT05809934 Active, not recruiting - Clinical trials for Nonalcoholic Steatohepatitis

A Study to Evaluate AZD2693 in Participants Who Are Carriers of the PNPLA3 148M Risk Allele With Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis

FORTUNA
Start date: March 15, 2023
Phase: Phase 2
Study type: Interventional

A Study to Evaluate the Efficacy, Safety and Tolerability of AZD2693 given by subcutaneous injection in adult participants with non-cirrhotic non-alcoholic steatohepatitis with fibrosis and who are carriers of the PNPLA3 148M Risk Allele

NCT ID: NCT05808556 Completed - High Blood Pressure Clinical Trials

Sticker Pad Containing Essential Oil in Volunteer With High Blood Pressure

Start date: October 2, 2020
Phase: N/A
Study type: Interventional

The aims of the study were to evaluate efficacy and safety of the sticker pads containing lavender and ylang ylang oil in high blood pressure volunteers

NCT ID: NCT05802927 Completed - Clinical trials for Diabetes Mellitus, Type 2

Diabetes-specific Formula (DSF) in Individuals With Type 2 Diabetes

Start date: July 5, 2023
Phase: N/A
Study type: Interventional

A randomized, controlled, crossover design with three treatments to determine the effects of diabetes-specific formula on glycemic control in individuals with type 2 diabetes.

NCT ID: NCT05801029 Recruiting - Clinical trials for Non-Small Cell Lung Cancer (NSCLC)

A Study to Investigate Safety and Efficacy of Osimertinib and Amivantamab in Participants With Non-small Cell Lung Cancer With Common Epidermal Growth Factor Receptor Mutations

OSTARA
Start date: July 18, 2023
Phase: Phase 2
Study type: Interventional

This study will assess the safety and efficacy of Osimertinib with Amivantamab as First-line Treatment in Participants with Epidermal Growth Factor Receptor Mutation-Positive, Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC).

NCT ID: NCT05791266 Completed - Healthy Clinical Trials

Safety of Sticker Pad Containing Essential Oil Containing Lavender and Ylang-ylang Oil

Start date: March 21, 2022
Phase: N/A
Study type: Interventional

The aims of the study were to evaluate safety of sticker pads containing lavender and ylang ylang oil in healthy volunteers.