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NCT ID: NCT04664595 Completed - Clinical trials for Complication of Device Insertion

Requirements of Propofol With Target Controlled Infusions for Supraglottic Airway Devices

Start date: June 2012
Phase: N/A
Study type: Interventional

to evaluate and compare the effect-site concentration of propofol with the TCI system for second-generation SGA device insertion between the I-gel™, Supreme™, ProSeal™ and Laryngeal Tube Suction II™. to determine the hemodynamic changes during insertion of supraglottic devices in patients undergoing elective surgery and any complications after device insertion.

NCT ID: NCT04657692 Completed - Obesity, Morbid Clinical Trials

Incidence of Complications Associated With Anesthesia in Obesity Parturient Undergoing Cesarean Delivery

Start date: December 29, 2020
Phase:
Study type: Observational

The incidence of obesity parturient has been increasing worldwide. There was a report revealing one third of pregnant women in United state considered obesity. Obesity is associated with increased in maternal and neonatal complications. Also, there was an increasing in the rate of cesarean delivery. Anesthetic management of the obese parturient is differ from non-obese parturients. There were higher risk of difficult intubation, failed intubation, pulmonary aspiration and difficult regional anesthesia such as spinal anesthesia or epidural catheter placement comparing with non-obese parturient. The aim of the study is to report complication associated with anesthesia in obese patients undergoing cesarean delivery in Single University hospital, Bangkok, THAILAND.

NCT ID: NCT04652700 Completed - Clinical trials for HIV Preexposure Prophylaxis

Oral Islatravir (MK-8591) Once-Monthly as Preexposure Prophylaxis (PrEP) in Men and Transgender Women Who Are at High Risk for HIV-1 Infection (MK-8591-024)

Impower-024
Start date: March 15, 2021
Phase: Phase 3
Study type: Interventional

The main purpose of the study is to evaluate the safety and tolerability of oral Islatravir (ISL) once monthly (QM) as Preexposure Prophylaxis (PrEP) in cisgender men who have sex with men (MSM) and transgender women (TGW) who have sex with men and who are at high risk of HIV-1 infection with 48 or 96 weeks of treatment and a minimum follow-up of 42 days.

NCT ID: NCT04642118 Completed - Clinical trials for Laparoscopic Surgery

Low-pressure Pulmonary Recruitment Maneuver to Decrease Post-laparoscopic Shoulder Pain in Gynecologic Surgery

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

Research objective to compare outcomes (shoulder pain score, wound pain score, post-operative residual pneumoperitoneum, lung complication, GI discomfort, administered additional analgesics, time to hospital staying) of using Pulmonary Recruitment maneuver with pressure 30 cmH2O, 40 cm H2O and control group in women with post laparoscopic gynecologic surgery in Rajavithi hospital.

NCT ID: NCT04622722 Completed - Clinical trials for Diabetes Mellitus, Type 2

Efficacy and Safety of Diabetes-specific Formula in Patients With Type 2 Diabetes Mellitus

Start date: August 22, 2018
Phase: N/A
Study type: Interventional

Hypothesis: the diabetes-specific formula Nutren diabetes provides better postprandial glucose control in patients with type 2 diabetes when compared to the isocaloric diet.

NCT ID: NCT04620850 Completed - Cesarean Section Clinical Trials

Effect of Acupressure on Recovery of Bowel Function in Patients Post Cesarean Section

Start date: November 15, 2020
Phase: N/A
Study type: Interventional

Research objectives To compare the efficacy of acupressure with no acupressure to examine time to first flatus in patient post cesarean section ; Acupressure at ST-36 Zusanli (lateral to anterior crest of tibia, in the tibialis anterior muscle) Research hypothesis Patients who received acupressure will have earlier flatus passage

NCT ID: NCT04611100 Completed - Biliary Obstruction Clinical Trials

Efficacy of Intraductal Radiofrequency Ablation in Combination With Metallic Biliary Stenting in Advanced Hilar Cholangiocarcinoma

Start date: April 1, 2020
Phase: N/A
Study type: Interventional

The study aim to evaluate the efficacy of intraductal radiofrequency ablation for unresetable hilar cholangiocarcinoma in addition to biliary stenting. The patient would be randomized into 1:1 ratio of conventional group who received biliary stenting alone, and RFA group who receive intraductal RFA before biliary stenting. Immediate complications as well as long term stent patency and patient survival would be studied.

NCT ID: NCT04608136 Completed - Metabolic Syndrome Clinical Trials

Egg Yolk and Underlying Metabolisms on Modifying HDL Levels in Individuals With Metabolic Syndrome

Start date: September 21, 2020
Phase: N/A
Study type: Interventional

This research compare the effects of low carbohydrate intake and consumption of 3 eggs per day, and low energy diet on diabetes control and biomarkers of CVD in obese people.

NCT ID: NCT04595370 Completed - Heart Failure Clinical Trials

Efficacy, Safety and Tolerability of AZD9977 and Dapagliflozin in Participants With Heart Failure and Chronic Kidney Disease

MIRACLE
Start date: January 26, 2021
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate the efficacy and safety of AZD9977 in combination with dapagliflozin compared with dapagliflozin alone and to assess the dose-response relationship, dapagliflozin alone and 3 doses of AZD9977 combined with dapagliflozin on urinary albumin to creatinine ratio (UACR). The study will be conducted in participants with heart failure (HF) with left ventricular ejection fraction (LVEF [below 60%]) and chronic kidney disease (CKD) with estimated glomerular filtration rate (eGFR [between ≥ 20 and ≤ 60 mL/min/1.73 m^2, with at least 20% of participants with eGFR ≥ 20 to <30 mL/min/1.73^2 and a maximum of 35% of participants with eGFR ≥ 45 mL/min/1.73 m^2]).

NCT ID: NCT04594551 Completed - Clinical trials for Rabies (Healthy Volunteers)

Study of Purified Vero Rabies Vaccine Compared With a Reference Rabies Vaccine as Simulated Rabies Post-Exposure Prophylaxis in Adults in Thaïland

Start date: October 11, 2020
Phase: Phase 3
Study type: Interventional

Primary Objective: To describe the immune response induced by VRVg-2 and Verorab vaccines at D14 and D35 when co-administered with Human Rabies Immunoglobulins (HRIG) at D0, according to the Zagreb (2-1-1) IM regimen in healthy adult subjects. Secondary Objective: Immunogenicity To describe the immune response induced by VRVg-2 and Verorab vaccines at D90 when co-administered with HRIG at D0, according to the Zagreb (2-1-1) IM regimen in healthy adult subjects. Safety To describe the safety profile of VRVg-2 and Verorab vaccines when co administered with HRIG at D0, after each vaccination.