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NCT ID: NCT01535859 Completed - Clinical trials for Ovarian Hyperstimulation Syndrome

Study of Cabergoline for Prevention of Ovarian Hyperstimulation Syndrome (OHSS) in In Vito Fertilization Cycles and Derivation of OHSS Biomarkers

Start date: April 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether cabergoline is effective in reducing the incidence and severity of Ovarian Hyperstimulation Syndrome (OHSS), especially for severe cases; and to derive biomarkers for the risk of developing OHSS.

NCT ID: NCT01533454 Completed - Obesity Clinical Trials

A Randomized Incentive-Based Weight Loss Trial in Singapore

Start date: September 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to test the extent to which incentives, when combined with an existing evidence-based weight loss program, improve weight loss and weight loss maintenance. It will also compare the cost-effectiveness of the incentive-based weight loss programs to the basic program without incentives.

NCT ID: NCT01533181 Completed - Clinical trials for Recurrent Small Cell Lung Carcinoma

Linsitinib or Topotecan Hydrochloride in Treating Patients With Relapsed Small Cell Lung Cancer

Start date: February 2012
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate how OSI-906 compares to Topotecan in trying to slow down the growth and/or progression of the tumors of participants with relapsed or recurrent Small Cell Lung Cancer. This study also plans to find out what effects, good or bad (side effects), OSI-906 has on participants and or Small Cell Lung Cancer. The study will also investigate if some proteins measured in the blood or tumor and some imaging features obtained from computed tomography (CT) scans can help predict whether OSI-906 or topotecan will be effective against Small Cell Lung Cancer.

NCT ID: NCT01528124 Completed - Healthy Volunteers Clinical Trials

A Study of LY3025876 in Healthy Volunteers

Start date: February 2012
Phase: Phase 1
Study type: Interventional

This trial is conducted in Singapore. The aim of this trial is to evaluate the safety and tolerability of the study drug in healthy people and investigate how much of the study drug gets into the blood stream and how long it takes the body to get rid of it. Information about any side effects that may occur will also be collected.

NCT ID: NCT01523587 Completed - Clinical trials for Carcinoma, Non-Small-Cell Lung

LUX-Lung 8: A Phase III Trial of Afatinib (BIBW 2992) Versus Erlotinib for the Treatment of Squamous Cell Lung Cancer After at Least One Prior Platinum Based Chemotherapy

Start date: March 5, 2012
Phase: Phase 3
Study type: Interventional

This randomised, open-label phase III trial will be performed in patients with advanced squamous cell carcinoma of the lung requiring second-line treatment after receiving first-line platinum-based chemotherapy. The primary objective of this trial is to compare the efficacy of BIBW 2992 to erlotinib as second-line treatment in this group of patients.

NCT ID: NCT01522807 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Study Of Three PF-05190457 Formulations In Healthy Volunteers

Start date: September 2011
Phase: Phase 1
Study type: Interventional

The purpose of the study is to evaluate the plasma drug concentrations of three formulations of PF-05190457 after administration of single doses to healthy volunteers.

NCT ID: NCT01521767 Completed - Clinical trials for Urinary Bladder, Overactive

Pharmacokinetics and Relative Bioavailability Study

Start date: October 2011
Phase: Phase 1
Study type: Interventional

A Single-Dose Pharmacokinetics And Relative Bioavailability Study Of Tolterodine From Two Microspheres In Powder Blend Extended Release Formulations Compared To The Commercial Extended Release Capsules

NCT ID: NCT01516645 Terminated - Solid Tumour Clinical Trials

Phase 1 Study of KHK2898 in Subjects With Advanced Solid Tumors

Start date: January 2012
Phase: Phase 1
Study type: Interventional

This is a two-part, Phase 1 open label, single-center, dose escalation study of KHK2898 as monotherapy in subjects with advanced solid tumors who no longer respond to standard therapy or for whom no standard therapy is available.

NCT ID: NCT01515358 Completed - Healthy Volunteers Clinical Trials

A Study to Evaluate the Safety and Tolerability of LY3000328 in Healthy Participants

Start date: February 2012
Phase: Phase 1
Study type: Interventional

The purposes of this study are to determine the safety and side effects of LY3000328, to determine how well the body will tolerate LY3000328, and to determine how long LY3000328 remains in the body.

NCT ID: NCT01513928 Completed - Healthy Clinical Trials

A Study To Compare The Pharmacokinetics Of Different Formulations Of PF-04937319 In Healthy Subjects

Start date: January 2012
Phase: Phase 1
Study type: Interventional

This study is designed to compare the pharmacokinetics of three different formulations of Pf-04937319