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NCT ID: NCT00251953 Terminated - Type 2 Diabetes Clinical Trials

GALLANT 8 Tesaglitazar Add-on to Metformin

Start date: July 2004
Phase: Phase 3
Study type: Interventional

This is a 24-week randomized double-blind, parallel-group, multi-center, placebo-controlled study of tesaglitazar (0.5 mg and 1 mg) given as add-on therapy to metformin in patients with type 2 diabetes, not adequately controlled on optimized metformin treatment and on diet/lifestyle advice during the titration and run-in period. The study comprises a 2-week enrollment period, 6 week placebo metformin titration period, 2-week single-blind run-in period, followed by a 24-week double blind treatment period and a 3-week follow-up period

NCT ID: NCT00251927 Completed - Clinical trials for Gastroesophageal Reflux

Esomeprazole (NEXIUM) vs. Surgery

LOTUS
Start date: October 2001
Phase: Phase 3
Study type: Interventional

The study investigates the efficacy of long-term treatment of esomeprazole compared to anti-reflux surgery in the control of gastroesophageal reflux disease by assessing time to treatment failure.

NCT ID: NCT00251914 Completed - Dyspepsia Clinical Trials

Nexium Dyspepsia/AST

Start date: December 2002
Phase: Phase 3
Study type: Interventional

The aim is to evaluate if the resolution of upper abdominal symptoms (pain or burning) during an acid suppressive test trial of esomprazole given daily for 7 days predicts symptoms resolution at the end of a subsequent treatment period of 7 weeks.

NCT ID: NCT00251901 Completed - Chest Pain Clinical Trials

Chest Pain Pilot Study

Start date: May 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy of Nexium® with placebo in relief of acid related pain or discomfort in the chest.

NCT ID: NCT00250003 Completed - Prevention Clinical Trials

Preventive Home Visits for Healthy Pensioners- a Randomized Controlled Trial

Start date: February 2000
Phase: Phase 1
Study type: Interventional

To investigate whether preventive home visits for healthy persons 75+, made by professional health workers, can change the pattern of care utilization and if the quality of life can improve. The hypothesis is that care utilisation will reduce, mortality decrease and quality of life improve.

NCT ID: NCT00249873 Completed - Atrial Fibrillation Clinical Trials

Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE A)

Start date: June 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if the combination of clopidogrel 75mg once daily (od) plus aspirin 100mg daily (recommended dose) is better than aspirin alone (100mg daily recommended dose) for preventing vascular events such as stroke and heart attack during approximately three years of follow-up in patients with atrial fibrillation associated with at least one major risk factor of vascular event such as elderly, blood pressure increase, history of stroke or transient ischemic attack or left ventricular dysfunction etc. The study will also accept patients with atrial fibrillation and unwilling to take oral anticoagulant therapy.

NCT ID: NCT00249795 Completed - Atrial Fibrillation Clinical Trials

Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE I)

ACTIVE I
Start date: June 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study was to determine if Irbesartan compared to Placebo would reduce the risk of vascular events such as heart attack, stroke, non-cerebral thromboembolic event and death in patients with Atrial Fibrillation (AF) and with at least one major risk of vascular events.

NCT ID: NCT00249249 Completed - Dyslipidemia Clinical Trials

Study to Compare the Efficacy of Pitavastatin With That of Atorvastatin in Lowering Cholesterol Levels

Start date: October 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy of pitavastatin with that of atorvastatin.

NCT ID: NCT00248170 Completed - Breast Cancer Clinical Trials

Comparison Trial of Letrozole to Anastrozole in the Adjuvant Treatment of Postmenopausal Women With Hormone Receptor and Node Positive Breast Cancer

FACE
Start date: December 2005
Phase: Phase 3
Study type: Interventional

Eligible patients will be post-menopausal hormone receptor- and lymph node-positive females who recently underwent primary surgery for breast cancer. Patients will be randomized to letrozole (2.5 mg per day for 5 years) vs anastrozole (1 mg per day for 5 years). Follow up will occur for 5 years after the completion of enrollment for survival and disease status updates.

NCT ID: NCT00247962 Completed - Clinical trials for Ankylosing Spondylitis

Study Evaluating Etanercept and Sulphasalazine in Ankylosing Spondylitis

Start date: December 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the efficacy of etanercept and sulphasalazine in the treatment of Ankylosing Spondylitis.