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NCT ID: NCT00429884 Recruiting - Atrial Fibrillation Clinical Trials

Studies of Disorders and Mechanisms Related to Atrial Fibrillation Before and After DC-Conversion.

Start date: January 2007
Phase: N/A
Study type: Observational

The purpose of this study is to investigate if breathing disorders are related to atrial fibrillation and if it is possible to predict recurrence of atrial fibrillation after DC-conversion by changes in heart rate variability and 24 hour ECG.

NCT ID: NCT00426803 Completed - Clinical trials for Acquired Bleeding Disorder

Recombinant Factor VIIa in Acute Intracerebral Haemorrhage

Start date: August 2002
Phase: Phase 2
Study type: Interventional

This trial is conducted in North America, Europe, Asia and Oceania. The purpose of this study is to evaluate safety and efficacy of Recombinant Factor VIIa in patients with acute intracerebral bleeding.

NCT ID: NCT00426764 Completed - Clinical trials for Peripheral T-cell Lymphoma

A Trial of Romidepsin for Progressive or Relapsed Peripheral T-cell Lymphoma

Start date: June 19, 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the activity of romidepsin in patients with progressive or relapsed peripheral T-cell lymphoma (PTCL) who have already been treated with systemic therapy.

NCT ID: NCT00426530 Completed - Breast Neoplasms Clinical Trials

Safety of Everolimus in Combination Therapy, in Patients With HER2-overexpressing Metastatic Breast Cancer

Start date: February 2007
Phase: Phase 1
Study type: Interventional

This study will look at different dose levels and regimens of everolimus combined with weekly trastuzumab and vinorelbine therapy in patients with HER-2 overexpressing metastatic breast cancer.

NCT ID: NCT00426101 Completed - Clinical trials for Hemophagocytic Lymphohistiocytosis

Treatment Protocol for Hemophagocytic Lymphohistiocytosis 2004

Start date: January 2004
Phase: Phase 3
Study type: Interventional

Without therapy HLH is often fatal, and often rapidly fatal. The treatment protocol HLH-94 has improved survival markedly as compared to the survival earlier. We now aim to improve survival further.

NCT ID: NCT00424047 Completed - Multiple Myeloma Clinical Trials

A Study of CC-5013 Plus Dexamethasone Versus Dexamethasone Alone in Previously Treated Subjects With Multiple Myeloma

Start date: January 1, 2003
Phase: Phase 3
Study type: Interventional

To compare the efficacy of oral CC-5013 in combination with oral pulse high-dose dexamethasone to that of placebo and oral high-dose pulse dexamethasone as treatment for subjects with relapsed or refractory multiple myeloma."

NCT ID: NCT00423319 Completed - Pulmonary Embolism Clinical Trials

Study of an Investigational Drug for the Prevention of Thrombosis-related Events Following Hip Replacement Surgery (ADVANCE-3)

Start date: March 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to learn whether apixaban can prevent the blood clots in the leg (deep vein thrombosis) and lung (pulmonary embolism) that sometimes occur after hip replacement surgery and to learn how apixaban compares with enoxaparin in preventing these clots. The safety of apixaban will also be studied

NCT ID: NCT00422058 Completed - Obesity Clinical Trials

The Effect of Liraglutide on Body Weight in Obese Subjects Without Diabetes

Start date: January 10, 2007
Phase: Phase 2
Study type: Interventional

This trial is conducted in Europe. The purpose of the 20-week trial is to investigate the efficacy of liraglutide to induce body weight loss and the purpose of the extension is to evaluate the long term safety and tolerability of liraglutide. Trial has the following trial periods: A 20-week randomised, double-blind, placebo-controlled, six-armed parallel-group, multi-centre, multinational trial with an open label orlistat comparator arm followed by an 84 week extension period.

NCT ID: NCT00421200 Completed - Hypotension Clinical Trials

Phase III Study of Hemospan® to Prevent Hypotension in Hip Arthroplasty

Start date: February 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether Hemospan is superior to Voluven for preventing hypotensive episodes during the perioperative period (from induction of spinal anesthesia until 6 hours after skin closure), and for reducing the incidence of operative and postoperative complications including organ dysfunction and failure until follow-up at one month following surgery. An independent Data Safety Monitoring Board (DSMB) will periodically evaluate the safety data collected during this trial.

NCT ID: NCT00421018 Completed - Allergic Asthma Clinical Trials

Optimization of Asthma Treatment Through Exhaled NO for Increased Asthma-Related Quality of Life (NOAK)

Start date: November 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether use of exhaled NO (nitric oxide) to regulate the anti-inflammatory treatment leads to increased asthma-related quality of life in patients with allergic asthma