Clinical Trials Logo

Filter by:
NCT ID: NCT00678314 Completed - Clinical trials for Carpal Tunnel Syndrome

Patient Controlled Regional Analgesia Following Carpal Tunnel Release: A Double-Blind Study Using Distal Perineural Catheters

Start date: January 2004
Phase: Phase 4
Study type: Interventional

This study was done with the primary aim of assessing the efficacy (as calculated by pain intensity difference) of patient controlled regional analgesia (PCRA) technique against oral analgesics, which has been the standard of care at our hospital. Secondary objectives were to analyze the volume and dose of LA that should be given, patient satisfaction and the long-term outcome for patients treated with the PCRA technique.

NCT ID: NCT00677807 Completed - COPD Clinical Trials

Safety, Tolerability and Efficacy of Indacaterol in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)

Start date: May 2008
Phase: Phase 3
Study type: Interventional

This study evaluated the 1 year safety, tolerability and efficacy of indacaterol against placebo in the treatment of Chronic Obstructive Pulmonary Disease (COPD) patients

NCT ID: NCT00677248 Completed - Clinical trials for Hypercholesterolemia

LDL-Cholesterol Lowering Effect of KB2115 as Add on to Ezetimibe

Start date: April 2008
Phase: Phase 2
Study type: Interventional

Eprotirome (KB2115) is a liver selective thyroid hormone that can induce hyperthyroidism in the liver, while an euthyroid state is preserved in the extrahepatic tissue. Eprotirome has in clinical trials demonstrated pronounced reduction of several independent risk factors for the development of atherosclerotic cardiovascular diseases. The purpose of the study is to assess the efficacy and safety of KB2115 as add on therapy to ezetimibe following 10 weeks of exposure compared to placebo. The aim of the study is to assess efficacy (LDL-cholesterol lowering effects) and safety of KB2115 and to define a clinically relevant dose or dose range for future studies.

NCT ID: NCT00676650 Terminated - Prostatic Neoplasms Clinical Trials

Sunitinib Plus Prednisone In Patients With Metastatic Castration-Resistant Prostate Cancer After Failure Of Docetaxel Chemotherapy

SUN 1120
Start date: July 2008
Phase: Phase 3
Study type: Interventional

This study will compare the safety and efficacy of sunitinib in combination with prednisone versus placebo and prednisone in patients that have metastatic castration-resistant prostate cancer that has progressed after treatment with a docetaxel-containing chemotherapy regimen. This is a second-line study.

NCT ID: NCT00676143 Terminated - Alzheimer Disease Clinical Trials

Study Evaluating the Safety and Efficacy of Bapineuzumab in Alzheimer Disease Patients

Start date: May 2008
Phase: Phase 3
Study type: Interventional

This is a study to evaluate the efficacy and safety of multiple doses of bapineuzumab in patients with mild to moderate Alzheimer Disease. Patients will receive either bapineuzumab or placebo. Each patient's participation will last approximately 1.5 years.

NCT ID: NCT00675324 Terminated - Colonoscopy Clinical Trials

Bowel Preparation Before Colonoscopy

Start date: April 2008
Phase: N/A
Study type: Interventional

Bowel preparation can be a troublesome procedure for patients undergoing colonoscopy. For patients with cardio-vascular and kidney disorders it may be dangerous with traditional bowel preparation with regard to salt and electrolyte balance. This study's purpose is to find out if nutritional drinks can replace traditional bowel preparation before colonoscopy in regard to Bowel purity degree, disturbances in the salt and electrolyte balance in the nutritional group versus the group that gets traditional bowel preparation. And if the patients tolerate nutritional drinks better than traditional bowel preparation.

NCT ID: NCT00673842 Recruiting - Clinical trials for Myocardial Infarction

Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction

REFINE-ICD
Start date: March 2011
Phase: Phase 3
Study type: Interventional

This study will assess whether an implantable defibrillator will increase the likelihood of survival in patients who have had a heart attack, have abnormal test results from a 24 hour heart monitor, and who have low normal heart function.

NCT ID: NCT00672477 Completed - Clinical trials for Opioid-Induced Constipation

Study Evaluating Subcutaneous Methylnaltrexone For Treatment Of Opioid-Induced Constipation In Patients With Advanced Illness

Start date: June 2008
Phase: Phase 4
Study type: Interventional

This study will evaluate the safety and efficacy of methylnaltrexone administered as subcutaneous injections in subjects who have opioid-induced constipation and an advanced illness. The hypothesis is that methylnaltrexone will be safe and effective in relieving opioid-induced constipation in these subjects.

NCT ID: NCT00672386 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Study of the Safety and Effectiveness of a R256918 in Patients With Type 2 Diabetes

Start date: December 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the effectiveness and safety of 12 weeks of treatment with R256918 in patients with Type 2 Diabetes Mellitus who are taking metformin. The primary measure of effectiveness is the change in concentration of glycated hemoglobin (HbA1c) during treatment. Glycated hemoglobin is a substance in red blood cells that is formed when blood sugar (glucose) attaches to hemoglobin and is a measure of diabetic status. Additional measures include fasting glucose, and lipid levels, and body weight. Safety assessments performed during the trial include laboratory tests, vital sign measurements, and adverse event reporting.

NCT ID: NCT00672282 Completed - Clinical trials for Non-Metastatic Prostate Cancer

Casodex vs Placebo in Non-Metastatic Early Prostate Cancer

SPCG6
Start date: October 1995
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to study the effect of adjuvant or immediate hormonal therapy, versus placebo, in subjects who have either undergone a primary therapy (principally radical prostatectomy or radiotherapy) or who were otherwise to be managed by watchful waiting.