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NCT ID: NCT00767169 Completed - Clinical trials for Edentatio (Toothlessness)

Bisphosphonate-coated Dental Implants

Start date: October 2008
Phase: Phase 2
Study type: Interventional

Dental implants (screws for fastening false teeth) have been coated with bisphosphonates (drugs that slow down removal of bone). Patients get one such screw and one without coating, by a surgeon who does not know which is which. The screws are compared by measuring how well fixed they are by a vibration measuring technique, and x-rays. The hypothesis is that the bisphosphonates will improve fixation.

NCT ID: NCT00765830 Completed - Clinical trials for Diabetes Mellitus, Type 2

Safety and Tolerability of Vildagliptin Versus Placebo in Patients With Type 2 Diabetes and Moderate or Severe Renal Insufficiency (28 Week Extension)

Start date: September 2008
Phase: Phase 3
Study type: Interventional

This clinical trial is designed to provide additional information on the safety and tolerability of vildagliptin (50 mg once daily (qd)) when used in patients with type 2 diabetes mellitus (T2DM) and moderate or severe renal insufficiency

NCT ID: NCT00765674 Completed - Hypertension Clinical Trials

Efficacy and Safety of Aliskiren/Amlodipine/Hydrochlorothiazide in Patients With Moderate-severe Hypertension

Start date: September 2008
Phase: Phase 3
Study type: Interventional

This study evaluated the efficacy (blood pressure lowering effect) and safety of aliskiren/amlodipine/hydrochlorothiazide in patients with moderate to severe hypertension.

NCT ID: NCT00765063 Completed - Diabetic Foot Ulcer Clinical Trials

The Effect Of Fragmin In The Treatment Of Neuroischaemic Foot Ulcers In Diabetic Patients (A6301086)

Start date: October 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The primary objective of this 6 month open-label extension trial is to evaluate long-term safety and tolerability of dalteparin in treatment of chronic neuroischaemic foot ulcers in diabetic patients with peripheral arterial occlusive disease (PAOD) and peripheral neuropathy.

NCT ID: NCT00764621 Completed - Clinical trials for Colorectal Neoplasms

Health Economic Evaluation of Primovist-enhanced Liver MRI

Start date: October 2008
Phase: Phase 4
Study type: Interventional

Patients with a history of colorectal cancer and known or suspected liver metastases who are scheduled for contrast-enhanced tomographic imaging will be included in this study. After randomization to either Primovist-enhanced MRI, extracellular contrast media (ECCM)-enhanced MRI or contrast-enhanced (CE)-CT outcomes and resource needs of the diagnostic work-up and treatment will be evaluated for each of the three imaging modalities. Main objectives of the study are to assess the proportion of patients for whom further imaging is required to come to a therapy decision and to evaluate the proportion of patients with intraoperatively modified surgical plans after Primovist-enhanced MRI as compared to ECCM-enhanced MRI and CE-CT.

NCT ID: NCT00763971 Completed - ADHD Clinical Trials

Randomized, Double-blind Safety and Efficacy Study of Lisdexamfetamine Dimesylate (LDX) in Children and Adolescents Aged 6-17

Start date: November 17, 2008
Phase: Phase 3
Study type: Interventional

The main aim of this study is to see if giving LDX to children and adolescents aged 6-17 years with ADHD decreases symptoms of ADHD.

NCT ID: NCT00763594 Terminated - Clinical trials for Major Depressive Disorder

Linköping University Relational and Interpersonal Psychotherapy Project

LURIPP
Start date: September 2008
Phase: Phase 2
Study type: Interventional

The study investigates the relative efficacy of Interpersonal Psychotherapy and Brief Relational Therapy for Major Depressive Disorder. The primary hypothesis is that there will be no mean difference in efficacy between treatments, but that Brief Relational Therapy will be more efficacious for more self-critical patients and Interpersonal Psychotherapy will be more efficacious for less self-critical patients.

NCT ID: NCT00761774 Completed - Epilepsy Clinical Trials

An Open-label, Multinational, Multicenter, Follow-up Study to Evaluate the Long-term Safety and Efficacy of Brivaracetam

Start date: November 2008
Phase: Phase 3
Study type: Interventional

The Sponsor wishes to develop brivaracetam as an anti-epileptic treatment in subjects 16 years and older with epilepsy. This study permits continued access to treatment for subjects who participated in a previous epilepsy study. The study will explore the long-term safety and efficacy of brivaracetam.

NCT ID: NCT00761501 Completed - Healthy Volunteer Clinical Trials

Phase I Study to Evaluate Bioavailability of Naproxen as PN400 Compared to Naproxen as Proxen S and Naprosyn E

Start date: September 2008
Phase: Phase 1
Study type: Interventional

The purpose of the study is to investigate the uptake in the body of naproxen; one of the two active substances in PN400. We also want to show that the body's uptake of naproxen given as PN400 is comparable to that of currently marketed naproxen tablets.

NCT ID: NCT00761449 Completed - AML Clinical Trials

Lenalidomide in High-risk MDS and AML With Del(5q) or Monosomy 5

Start date: October 2007
Phase: Phase 2
Study type: Interventional

The aim of this study is to investigate the efficacy of lenalidomide in high risk MDS or AML with chromosome 5 aberrations.