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NCT ID: NCT00787072 Terminated - Healthy Volunteers Clinical Trials

AZD8075 Single Ascending Dose Study

Start date: October 2008
Phase: Phase 1
Study type: Interventional

The aim of this study is to assess the safety, tolerability and pharmacokinetics of single ascending oral doses of AZD8075 in healthy male volunteers

NCT ID: NCT00785954 Completed - Clinical trials for Cardiovascular Diseases

Safety and Efficacy Study of KAI-9803 to Treat Subjects With ST Elevation Myocardial Infarction [Heart Attack]

PROTECTION AMI
Start date: November 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether KAI-9803 is safe and effective in reducing infarct size in subjects with ST elevation myocardial infarction (heart attack) undergoing a percutaneous coronary intervention (PCI). A select number of sites will also participate in a substudy where eligible patients will undergo an additional procedure;cardiac magnetic resonance imaging.

NCT ID: NCT00785785 Completed - Clinical trials for Gastrointestinal Stromal Tumor (GIST)

A Study of Nilotinib Versus Imatinib in GIST Patients

ENESTg1
Start date: March 2009
Phase: Phase 3
Study type: Interventional

This study will evaluate efficacy and safety of nilotinib versus imatinib in adult patients with unresectable or metastatic gastrointestinal stromal tumors (GIST).

NCT ID: NCT00785317 Recruiting - Clinical trials for Hormone Replacement Therapy

Effects of Estradiol on Menopausal Breast

BrAVA
Start date: November 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effects on breast in postmenopausal women randomized to either oestradiol in combination with DRSP or E2 in combination with NETA during six months.

NCT ID: NCT00784654 Completed - ADHD Clinical Trials

Double-blind, Placebo-controlled, Randomised Withdrawal, Extension, Safety and Efficacy Study of LDX in Children and Adolescents Aged 6-17

Start date: January 27, 2009
Phase: Phase 3
Study type: Interventional

The main aim of this study is to evaluate the long-term maintenance of efficacy of LDX after administered to children and adolescents aged 6-17 with ADHD for at least 6 months

NCT ID: NCT00783744 Completed - Clinical trials for Diabetes Mellitus, Type 2

Insulin Glargine Combination Therapies in Type II Diabetics

LAPTOP
Start date: December 2001
Phase: Phase 3
Study type: Interventional

To compare efficacy of combination therapy of insulin glargine plus glimepiride and metformin versus 2 injections insulin monotherapy with premixed insulin NPH 30/70 bid in terms of change of HbA1c (baseline to endpoint) to show non-inferiority of insulin glargine plus glimepiride and metformin.

NCT ID: NCT00783510 Completed - Clinical trials for Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis (JIA) Registry

STRIVE
Start date: July 11, 2008
Phase:
Study type: Observational

This is a global registry, to evaluate the long-term safety of Humira® in patients with moderate to severe polyarticular Juvenile Idiopathic Arthritis (JIA), that are treated as recommended in the Humira® product label. Patients treated with MTX will be considered a reference group. Patients will be followed in both the Humira® and Methotrexate (MTX) arms for 10 years from the enrollment date into one of the treatment arms.

NCT ID: NCT00783042 Completed - Atherosclerosis Clinical Trials

Exploratory Study of Coronary Flow Reserve Measurements, a Non-Invasive Method for Coronary Function Measurements

Start date: October 2008
Phase: Phase 0
Study type: Interventional

The aim of this study is to investigate whether the non-invasive ultrasound method for assessment of coronary blood flow, transthoracic Doppler echocardiography-coronary flow reserve (TTDE-CFR), can be used to measure drug effects.

NCT ID: NCT00782171 Completed - Partial Edentulism Clinical Trials

Evaluation of Immediate Versus Delayed Loading of Dental Implants With a Modified Surface

Start date: July 2004
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the performance of a new dental implant with a modified surface in different loading protocols.

NCT ID: NCT00781690 Completed - Clinical trials for Chronic Kidney Failure

Reduction of Heparin Dose in Dialysis With Evodial System

RHODES
Start date: September 2008
Phase: N/A
Study type: Interventional

The current clinical study aims at defining an index of Anti Xa, which is the marker to evaluate the activity of heparin, at the end of the dialysis treatment and so showing the possibility to decrease heparin doses during hemodialysis when using Evodial hemodialyzer. Actually, an elevated value of AntiXa at the end of the dialysis treatment increases the risk of bleeding for patients with diabetic retinopathy, or for instance in case of fall at home.