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NCT ID: NCT01709539 Completed - Cancer Clinical Trials

Clinical Evaluation of a New Cancer Diagnosis Center at Kristianstad General Hospital, Sweden

CPF-DC
Start date: October 2012
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate a new cancer diagnosis center (Diagnostiskt Centrum, DC) in Kristianstad, Sweden. Patients aged ≥ 18 years who are suspected of having serious illness but who have no organ-specific symptoms will be referred to the DC for further investigation after preliminary assessment in primary care. The overall purpose of the study is to evaluate whether the DC meets its target time for diagnosing cancer. In addition, we will evaluate secondary issues, such as survival, to determine whether this pilot project merits extension to other parts of southern Sweden.

NCT ID: NCT01709097 Completed - Clinical trials for Medication Adherence

Compliance/Adherence After Kidney Transplant, With or With Out Med-O-Wheel™.

C/A
Start date: June 2011
Phase: N/A
Study type: Observational

Background: Adherence to the immunosuppressive drug regimen is critical to the outcome after an organ transplant. Patients need to take their prescribed medications and attend their appointments with the doctor. Based on previous studies in other European countries, the cost of non-compliance after organ transplantation in Sweden is >SEK 35 million/year. Patients who lose their graft both lose quality of life and have decreased expected survival; moreover, retransplantation may be hampered by new HLA antibodies. Question: The primary question is whether Med-O-Wheel™ can improve compliance to the prescribed medication regimen in renal transplant patients. Methods and materials: All kidney transplant patients at Karolinska University Hospital, Huddinge, will be given information about the study and will then be asked to participate. Participants will be randomized into two arms, one arm with and one with out Med-O-Wheel™. The 80 included patients will be closely monitored for 1 year regarding intake of prescribed medications. Med-O-Wheel™ is an electronic medication dispenser that records the date and time of each occasion when the patient takes medications from the dispenser. It has a SIM card and text messaging capabilities. Addoz Portal™ is a web-based application that makes it possible to monitor and analyse medication intake. Each event in the medication dispenser is registered in the portal, which communicates with the care provider/support person by text message, e-mail or telephone. Significance of the study: In the future it may be possible to improve compliance in transplant patients. In particular, patients will feel secure since they will receive confirmation through the portal that they are taking their medications safely and accurately.

NCT ID: NCT01708811 Terminated - Hyponatremia Clinical Trials

Hyponatremia and Myometrium Contractility. An Invitro Study

Start date: October 2012
Phase: N/A
Study type: Observational

Hyponatremia during labour has been associated with prolonged labour, and increased incidence of instrumental delivery and emergency caesarean section. Sodium influx in myometral cells are involved in contractility,and and influence of hyponatraemia on contractility can be suspected.

NCT ID: NCT01708174 Completed - Medulloblastoma Clinical Trials

A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB)

Start date: May 6, 2013
Phase: Phase 2
Study type: Interventional

This Phase II study evaluated the safety and efficacy of LDE225 in adult and pediatric patients with Hh-pathway activated, relapsed MB.

NCT ID: NCT01708109 Terminated - Cholelithiasis Clinical Trials

Optimal Handling of Common Bile Duct Calculus, a Prospective Study

Start date: November 27, 2011
Phase: N/A
Study type: Interventional

The purpose is to study natural process of gallstones in common bile duct, stones less than or equal to 6 mm. And if the gallstones give any complications under 1 year follow up. The second outcome is to study side-effects of gallstones removed with surgery.

NCT ID: NCT01708096 Completed - Clinical trials for Diabetes Mellitus Typ 2 and Obesity

Mechanisms Behind Antidiabetic Effects by Gastric By-pass

Start date: October 2009
Phase: N/A
Study type: Interventional

The aim of the study is to develop new strategies in treatment of continuous increasing number of patients with type 2 diabetes by understanding how bariatric surgery cures or improves this condition.

NCT ID: NCT01708083 Completed - Polymorphism Clinical Trials

Polymorphids an mRNA Expression in Obese Genes

Start date: January 2010
Phase: N/A
Study type: Observational

Fat tissue from omenta, thigh and abdomen taken under anesthesia on subjects undergoing laparoscopic surgery, cholecystectomy, reflux surgery or gastric by-pass (GBP). Are there any difference in polymorphids and/or mRNA expression in genes significant for developing obesity, between normal weight and obese individuals, with or without diabetes typ 2 . Are there any difference in polymorphids and/or mRNA expression in different types of fat tissue

NCT ID: NCT01708057 Terminated - Clinical trials for Chronic Obstructive Pulmonary Disease

A Single-dose Study to Investigate the Effects of 4 Different Doses of Inhaled AZD8683 in Chronic Obstructive Pulmonary Disease (COPD) Patients

Start date: October 2012
Phase: Phase 2
Study type: Interventional

This study in Chronic Obstructive Pulmonary Disease (COPD) patients will investigate the bronchodilatory effect of AZD8683. AZD8683 will be tested versus placebo and an active comparator.

NCT ID: NCT01707680 Terminated - Critical Illness Clinical Trials

Non-interventional Comparison of Sedatives on Weaning From Mechanical Ventilation in Intensive Care Patients

NICEWEAN
Start date: June 1, 2012
Phase:
Study type: Observational

The purpose of this study is to determine whether the use of different sedatives affect the weaning process from mechanical ventilation in intensive care patients.

NCT ID: NCT01707134 Completed - Diabetes Clinical Trials

Safety and Efficacy of Insulin Aspart in Subjects With Type 1 Diabetes

Start date: September 1997
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe. The aim of this trial is to evaluate the safety profile of insulin aspart in subjects with type 1 diabetes having participated in trial ANA/DCD/035.