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NCT ID: NCT00459667 Completed - Clinical trials for Multiple Sclerosis, Relapsing-Remitting

BEYOND Follow-up: Betaferon®/Betaseron® Efficacy Yielding Outcomes of a New Dose

Beyond
Start date: May 2007
Phase: Phase 3
Study type: Interventional

The BEYOND Follow-Up study will give patients who participated in the preceding BEYOND study the opportunity to continue treatment with the 500µg dose of interferon beta (IFNB) 1b and will further investigate the safety and tolerability profile of interferon beta 1b 500µg during longer-term treatment.

NCT ID: NCT00459654 Completed - Prostate Cancer Clinical Trials

A Placebo-controlled Phase II Study of Bone-targeted Radium-223 in Symptomatic Hormone-refractory Prostate Cancer

Start date: February 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of the investigational radioisotope Radium-223 in treatment of men with prostate cancer and bone metastases that no longer respond to hormonal treatment.

NCT ID: NCT00459550 Completed - Alzheimer's Disease Clinical Trials

A Clinical Study to Assess Single and Repeat Doses of a New Medication (GSK933776) in Patients With Alzheimer's Disease

Start date: March 12, 2007
Phase: Phase 1
Study type: Interventional

A study to investigate the safety and tolerability of both single and multiple intravenous administration of GSK933776 in patients with Alzheimer's Disease.

NCT ID: NCT00457691 Completed - Clinical trials for Metastatic Colorectal Cancer

Study Of FOLFIRI Chemotherapy With Or Without Sunitinib In Patients With Metastatic Colorectal Cancer

Start date: June 2007
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate the safety and efficacy of FOLFIRI (Irinotecan, Leucovorin and 5 Fluorouracil) chemotherapy when combined with sunitinib or FOLFIRI chemotherapy without adding sunitinib as the first line treatment of patients with metastatic colorectal cancer.

NCT ID: NCT00457002 Completed - Pulmonary Embolism Clinical Trials

Study of Apixaban for the Prevention of Thrombosis-related Events in Patients With Acute Medical Illness

ADOPT
Start date: June 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to learn if apixaban can prevent blood clots in the leg (deep vein thrombosis [DVT]) and lung (pulmonary embolism [PE]) that sometimes occur within patients hospitalized for acute medical illness, and to learn how apixaban compares to enoxaparin (Lovenox®) for preventing these clots. The safety of apixaban will also be studied.

NCT ID: NCT00456027 Completed - Clinical trials for Latent Autoimmune Diabetes in Adult (LADA)

Safety of Diamyd® in Patients With LADA (Latent Autoimmune Diabetes in Adult)

Start date: December 2004
Phase: Phase 2
Study type: Interventional

This is a study to investigate the safety of 20ug Diamyd® (rhGAD65 formulated in Alhydrogel®), administered subcutaneously four weeks apart in patients with Latent Autoimmune Diabetes in Adult (LADA).

NCT ID: NCT00455923 Completed - Asthma Clinical Trials

SERETIDE Vs FLIXOTIDE In Mild Persistent Asthma (GINAII)

Start date: May 3, 2005
Phase: Phase 4
Study type: Interventional

An 18 months randomised double-blind study with two parallel arms with start dose of inhaled SERETIDE 50/100mcg BD or FLIXOTIDE 100mcg BD, Phase I is 6 months where the patient will be up-titrated until well controlled is achieved, After 6 months the treatment continues without changes during 9 months = PhaseII. The aim is to investigate and evaluate the assumption that the combination therapy with SERETIDE controls mild persistent asthma better than inhaled corticosteroids(FLIXOTIDE) alone.

NCT ID: NCT00455000 Completed - Alzheimer's Disease Clinical Trials

A Phase I, Single IV Dose Of PF-04360365 In Adults With Mild To Moderate Alzheimer's Disease

Start date: March 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study is determine whether a single IV dose of PF-04360365 is safe and well tolerated in Adults with Mild to Moderate Alzheimer's disease.

NCT ID: NCT00454545 Completed - Crohns Disease Clinical Trials

Atorvastatin in Moderate Active Crohns Disease

Start date: October 2006
Phase: Phase 2
Study type: Interventional

Open pilot study to collect information regarding the effect of atorvastatin on patients with active Crohns disease.

NCT ID: NCT00452530 Completed - Pulmonary Embolism Clinical Trials

Study of an Investigational Drug for the Prevention of Thrombosis-related Events Following Knee Replacement Surgery

ADVANCE-2
Start date: June 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to learn whether apixaban prevents the development of blood clots in the leg (deep vein thrombosis) and lung (pulmonary embolism), which sometimes occur after knee replacement surgery, and to compare the efficacy of apixaban with that of enoxaparin (Lovenox®) in the prevention of these clots. The safety of apixaban will also be studied.