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NCT ID: NCT02435043 Completed - Stroke Clinical Trials

A Trial of Nature-based Post-stroke Fatigue Rehabilitation (NASTRU)

NASTRU
Start date: August 2012
Phase: N/A
Study type: Interventional

The aim of NASTRU was to examine whether ten weeks of nature-based rehabilitation, as add-on to standard management, could influence post-stroke fatigue (primary outcome), depression, work ability or functional outcome (secondary outcomes), compared to controls.

NCT ID: NCT02434549 Terminated - Pain Clinical Trials

Botulinum Toxin-A as a Treatment for Chronic Muscle-Related Pain in Adults With Spastic Cerebral Palsy: a Randomized Controlled Trial

BATCP
Start date: August 2015
Phase: Phase 2
Study type: Interventional

The purpose of this double-blinded, placebo-controlled study is to test if treatment with Botulinum toxin-A is effective in reducing chronic muscle-related pain in adults with spastic cerebral palsy.

NCT ID: NCT02432846 Completed - Clinical trials for Renal Cell Carcinoma, Metastatic

Intratumoral Vaccination With Intuvax Pre-nephrectomy Followed by Sunitinib Post-nephrectomy vs Sunitinib Post-nephrectomy in Newly Diagnosed Metastatic Renal Cell Carcinoma (mRCC)

MERECA
Start date: April 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare tumor response, progression free survival (PFS) and overall survival (OS) in newly diagnosed mRCC patients treated with Intuvax (INN: ilixadencel) pre-nephrectomy followed by Sunitinib post-nephrectomy vs Sunitinib post-nephrectomy patients.

NCT ID: NCT02431780 Completed - Epilepsy Clinical Trials

A Multicentre Clinical Investigation of a Decision Support Algorithm for Neonatal Seizure Detection

ANSeR
Start date: February 12, 2015
Phase: N/A
Study type: Interventional

The ANSeR Clinical Investigation is a multi-centre, randomised, controlled, clinical investigation of a standalone decision support Algorithm for Neonatal Seizure Recognition, the ANSER Software system.

NCT ID: NCT02431416 Completed - Puberty, Precocious Clinical Trials

Effect of a GnRH Injection on Ghrelin Concentrations in Girls With Suspected Premature Puberty

Start date: May 2015
Phase: N/A
Study type: Interventional

The purposes of the study is to investigate whether circulating levels of ghrelin decreases after an iv injection of GnRH in girls with suspected central premature puberty and to investigate the effects of different post sampling handling on the preservation of acylated ghrelin.

NCT ID: NCT02429908 Completed - Clinical trials for Degenerative Disc Disease

Post-Market Surveillance Study of the TM Ardis Interbody Fusion System

Start date: March 2014
Phase: Phase 4
Study type: Interventional

This study is a post-market clinical follow-up study to fulfill the post-market surveillance obligations according to Medical Device Directive and MEDDEV 2.12-2_Rev2_January 2012. The data collected from this study will serve the purpose of confirming safety and performance of the TM Ardis implant. The goal of this study is to demonstrate that implant is effective in reducing patient disability.

NCT ID: NCT02427555 Completed - Healthy Subjects Clinical Trials

Effects of Barley Based Food Products on Metabolism and Gut Microflora

Start date: April 2015
Phase: N/A
Study type: Interventional

The main objective is to investigate gut microflora composition in relation to cardiometabolic risk markers, and to investigate the effects of 3 days intervention with a barley kernel based product on these variables.

NCT ID: NCT02427165 Completed - Asthma Clinical Trials

Comparison of RPL554 With Placebo and Salbutamol in Asthmatic Patients

Start date: April 2015
Phase: Phase 2
Study type: Interventional

The number of people with of asthma and allergy is still increasing and a large number of patients still do not have their asthma well controlled. There is therefore a need for new asthma treatments that work well and have less side effects. The study compares a new experimental drug RPL554 with a marketed asthma drug (salbutamol) and placebo.

NCT ID: NCT02425891 Completed - Clinical trials for Triple Negative Breast Cancer

A Study of Atezolizumab in Combination With Nab-Paclitaxel Compared With Placebo With Nab-Paclitaxel for Participants With Previously Untreated Metastatic Triple-Negative Breast Cancer (IMpassion130)

Start date: June 23, 2015
Phase: Phase 3
Study type: Interventional

This multicenter, randomized, double-blind study evaluated the efficacy, safety, and pharmacokinetics of atezolizumab (MPDL3280A) administered with nab-paclitaxel compared with placebo in combination with nab-paclitaxel in participants with locally advanced or metastatic triple-negative breast cancer (TNBC) who have not received prior systemic therapy for metastatic breast cancer (mBC). The safety of single-agent nab-paclitaxel has been determined in previous studies of participants with mBC and the safety data to date suggest that atezolizumab can be safely combined with standard chemotherapy agents.

NCT ID: NCT02425644 Completed - Multiple Sclerosis Clinical Trials

Oral Ponesimod Versus Teriflunomide In Relapsing MUltiple Sclerosis

OPTIMUM
Start date: June 4, 2015
Phase: Phase 3
Study type: Interventional

International clinical trial to compare ponesimod and teriflunomide in relapsing multiple sclerosis