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NCT ID: NCT00659295 Completed - Clinical trials for Diabetes Mellitus, Type 2

Observational Study to Evaluate the Safety of Levemir® in Diabetes

PREDICTIVEâ„¢
Start date: June 2004
Phase: N/A
Study type: Observational

This study is conducted in Africa, Asia, Europe, Japan and South America. The aim of this observational study is to evaluate the incidence of serious adverse reactions (SARs) while using Levemir® (insulin detemir) under normal clinical practice conditions. Study conducted globally in 26 countries. Some countries participated in the study for only 3 months (Austria, Brazil, Denmark, Germany, Israel, Lebanon, Slovenia, Russia, and Turkey), while others extended their participation to 6 (Belgium/Luxembourg, Czech Republic, Greece, India, Italy, Netherlands, Saudi Arabia, South Africa, South Korea, Sweden, Tunisia, and United Kingdom/Ireland) and 12 months (Finland, France, and Japan), respectively.

NCT ID: NCT00658567 Completed - Clinical trials for Parkinson's Disease Psychosis

A Study of Safety and Efficacy of Pimavanserin (ACP-103) in Patients With Parkinson's Disease Psychosis

Start date: March 2008
Phase: Phase 3
Study type: Interventional

This study will evaluate the safety and efficacy of two dose levels of pimavanserin (ACP-103) compared to placebo in patients with Parkinson's disease psychosis.

NCT ID: NCT00658515 Completed - Clinical trials for Coronary Heart Disease

A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome

Start date: April 2008
Phase: Phase 3
Study type: Interventional

This study will evaluate the potential of RO4607381 to reduce cardiovascular morbidity and mortality in stable coronary heart disease patients with recent Acute Coronary Syndrome (ACS) and evaluate the long term safety profile of the drug. Eligible patients in stable condition will be randomized to receive either RO4607381 600mg po or placebo po, daily, together with a background of standard medication for ACS (including aspirin, antihypertensives and statins). The anticipated time on study treatment is 2+ years, and the target sample size is 15,600 individuals.

NCT ID: NCT00658268 Completed - Clinical trials for Aseptic Loosening of the Hip Prosthesis

Bisphosphonates and Impaction Grafting in Hip Revision

Start date: March 2008
Phase: Phase 2
Study type: Interventional

The primary focus of this study is to investigate whether increased bone density of the graft in revision arthroplasty of the hip can cause a decreased micromotion of the implant relative to the femur.

NCT ID: NCT00657150 Completed - Clinical trials for Venous Thromboembolism

Dabigatran Etexilate Compared With Enoxaparin in Prevention of Venous Thromboembolism (VTE) Following Total Hip Arthroplasty

Start date: March 2008
Phase: Phase 3
Study type: Interventional

The primary objective of the trial is to demonstrate non-inferiority of 220 mg oral dabigatran etexilate compared to 40 mg subcutaneous enoxaparin administered once daily. Safety and efficacy will be compared between the treatment groups.

NCT ID: NCT00655863 Completed - Diabetes Mellitus Clinical Trials

Efficacy of Alogliptin and With Pioglitazone in Patients With Type 2 Diabetes.

Start date: July 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy of Alogliptin, once daily (QD), taken by itself and with pioglitazone on postprandial lipid measures in type 2 diabetes.

NCT ID: NCT00655265 Completed - Clinical trials for Familial Hypercholesterolemia

A Study of the Safety and Efficacy of Patients With Familial Hypercholesterolaemia Taking Colesevelam as add-on Therapy to Their Existing Medication

Start date: August 2007
Phase: Phase 4
Study type: Interventional

This study is designed to assess whether colesevelam given as third line treatment added to a maximal tolerated and stable dose of a statin and ezetimibe is able to further decrease the level of LDL cholesterol in a safe and efficient manner in difficult to treat Familial Hypercholesterolaemia patients who are not at their target level of LDL cholesterol.

NCT ID: NCT00654940 Completed - Nerve Pain Clinical Trials

A Study To Assess The Ability Of A Crossover Study Design To Detect The Efficacy Of Pregabalin In Post-Traumatic Neuropathic Pain Patients

Start date: May 2008
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess whether a cross-over type study design in post-traumatic neuropathic patients can be used to assess the activity of potential analgesic agents

NCT ID: NCT00653926 Completed - Postoperative Pain Clinical Trials

Local Infiltration Analgesia Following Unicompartmental Knee Arthroplasty

Start date: September 2005
Phase: N/A
Study type: Interventional

The primary aim of this study is to evaluate if intra- and postoperative administration of ropivacaine, ketorolac and epinephrine into the operating field would affect hospital stay. Secondary end-points are morphine consumption, pain intensity and side effects. In an attempt to assess the safety of this technique, knee function and patient satisfaction scores are assessed up to 6 months after surgery.

NCT ID: NCT00652977 Completed - Clinical trials for Perineal Lacerations

Ritgens Maneuver for the Prevention of Anal Sphincter Tears at Delivery: A Randomized Controlled Trial

Start date: December 1999
Phase: N/A
Study type: Interventional

The aim of the investigation was to assess whether routine use of the modified Ritgen´s maneuver decreases the risk of anal sphincter injury at delivery, compared with simple manual protection of the perineum.Ritgen´s maneuver means that the fetal chin is reached for between the anus and the coccyx and pulled anteriorly, while using the fingers of the other hand on the fetal occiput to control speed of delivery and keep flexion of the fetal neck.