Clinical Trials Logo

Filter by:
NCT ID: NCT02131662 Completed - Leiomyoma Clinical Trials

Bay1002670, Fibroids, Safety and Efficacy EU,US,Can, Jap

ASTEROID 1
Start date: May 15, 2014
Phase: Phase 2
Study type: Interventional

The study is performed to assess the efficacy and safety of different doses of BAY1002670 in subjects with uterine fibroids. The dose-response relationship will be evaluated. Further, the study aims to establish a population pharmacokinetic/pharmacodynamic relationship for BAY1002670 in subjects with uterine fibroids. To assess the efficacy of BAY1002670 the interchangeability of menstrual pictogram and alkaline hematin method for the judgement of menstrual blood loss will be assessed.

NCT ID: NCT02130557 Completed - Clinical trials for Leukemia, Myelogenous, Chronic, Breakpoint Cluster Region-Abelson Proto-oncogene (BCR-ABL) Positive

A Multicenter Phase 3, Open-Label Study of Bosutinib Versus Imatinib in Adult Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia

Start date: July 15, 2014
Phase: Phase 3
Study type: Interventional

Phase 3, 2-arm, randomized, open label trial. Patients will be randomized to receive bosutinib or imatinib for the duration of the study.

NCT ID: NCT02127801 Completed - Allergy Clinical Trials

Single Ascending-dose Study of the Efficacy, Safety, Tolerability, and Pharmacokinetics of REGN1908-1909 in Allergic, Adult Participants

Start date: October 31, 2014
Phase: Phase 1
Study type: Interventional

The purposes of this study are to assess the efficacy, safety and tolerability of a single dose of REGN1908-1909 in allergic adult participants, to collect information about how much REGN1908-1909 is in blood over time and to collect information about how the body reacts to REGN1908-1909.

NCT ID: NCT02127476 Completed - Alzheimer's Disease Clinical Trials

A Study of Single and Multiple Doses of KHK6640 in Subjects With Prodromal or Mild to Moderate Alzheimer's Disease

Start date: July 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of KHK6640, given as a single dose and as multiple doses in patients with Prodromal Alzheimer's Disease (AD) or Mild to Moderate AD.

NCT ID: NCT02124213 Completed - Healthy Clinical Trials

A Study To Evaluate D1 Receptor Occupancy (RO) Following Single Dose of PF-06412562 In Healthy Male Volunteers

PET
Start date: September 2014
Phase: Phase 1
Study type: Interventional

This study will evaluate D1 Receptor Occupancy (RO) following a single dose of PF-06412562 In healthy male volunteers

NCT ID: NCT02123823 Completed - Neoplasms Clinical Trials

BI 836845 in Estrogen Receptor Positive Metastatic Breast Cancer

Start date: May 15, 2014
Phase: Phase 1
Study type: Interventional

Phase Ib / II study to determine the Maximum Tolerated Dose and Recommended Phase II Dose, and to evaluate the safety and antitumour activity, of BI 836845 and everolimus in combination with exemestane in women with HR+/HER2- advanced breast cancer

NCT ID: NCT02121197 Completed - Clinical trials for Diabetic Macular Edema

Retrospective Trial on the Efficacy and Safety of Intravitreal Ozurdex in Patients With Diabetic Macular Edema.

ARTES
Start date: August 2014
Phase:
Study type: Observational

To review the safety and efficacy of injections with Ozurdex (700 μg dexamethasone) in clinical practice management of patients with DME.

NCT ID: NCT02120963 Completed - Clinical trials for Rheumatoid Arthritis

Fatigue in People With Rheumatoid Arthritis- Randomized Controlled Trial

RAFatigueRCT
Start date: November 2013
Phase: N/A
Study type: Interventional

Aim: To study if a person-centered physical therapy intervention program contributes to diminished fatigue in people with Rheumatoid Arthritis (RA).

NCT ID: NCT02119871 Completed - Brain Ischemia Clinical Trials

Comparative Effectiveness of Unilateral vs. Bilateral Pulmonary Collapse in Cardiac De-airing

Start date: January 2014
Phase: N/A
Study type: Interventional

To compare the effectiveness of unilateral pulmonary collapse (right lung) to bilateral pulmonary collapse for cardiac de-airing in open left-sided heart surgery.

NCT ID: NCT02119481 Completed - Breast Cancer Clinical Trials

Effects of Mindfulness Meditation and Stress Management After Breast Cancer

Start date: May 2014
Phase: N/A
Study type: Interventional

The primary aim of this study is to examine the effects of a mindfulness-based stress reduction training program, delivered in individual web-based sessions, among breast cancer patients. The objectives are to study and answer questions regarding effects of the such training in a randomized controlled trial including the following outcome measures: physical and mental health status, perceived stress, post-traumatic stress symptoms, psychological well-being, and sleep quality. In addition to the primary aim, the investigators plan to explore potential mechanisms through which mindfulness training lead to improvement in perceived stress, well-being and sleep-quality. This will be studied by mediational analyses.