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NCT ID: NCT00515619 Completed - Epilepsy Clinical Trials

Assess Safety and Efficacy of Lacosamide in Patients With Partial Seizures

Start date: December 2004
Phase: Phase 3
Study type: Interventional

The main purpose of this trial is to determine safety and efficacy of Lacosamide under long term therapy.

NCT ID: NCT00514683 Completed - Pulmonary Fibrosis Clinical Trials

Safety And Efficacy of BIBF 1120 in Idiopathic Pulmonary Fibrosis

Start date: August 2007
Phase: Phase 2
Study type: Interventional

The general purpose of this trial is to investigate the efficacy and safety of 4 dose strategies of BIBF 1120 treatment for 12 months, compared to placebo in patients with idiopathic pulmonary fibrosis. The primary objective of this study is to demonstrate whether at least one dose strategy is superior to placebo in patients with IPF, in modifying the rate of decline of Forced Vital Capacity (FVC). As a secondary objective, additional parameters will be assessed in order to differentiate between dose strategies on the basis of safety and efficacy

NCT ID: NCT00510406 Completed - Clinical trials for Lower Urinary Tract Symptoms

A Study With Combination Treatment (Tamsulosin Hydrochloride and Solifenacin Succinate) in Male Patients With LUTS/BPH

SATURN
Start date: January 2007
Phase: Phase 2
Study type: Interventional

The study will examine the efficacy,safety and tolerability of combination therapy of tamsulosin and solifenacin compared to placebo and monotherapy of tamsulosin and solifenacin in the treatment of males with LUTS associated with BPH.

NCT ID: NCT00509145 Completed - Multiple Sclerosis Clinical Trials

Safety and Efficacy of Orally Administered Laquinimod Versus Placebo for Treatment of Relapsing Remitting Multiple Sclerosis (RRMS)

ALLEGRO
Start date: November 13, 2007
Phase: Phase 3
Study type: Interventional

Determination the efficacy of daily oral treatment with laquinimod 0.6 mg capsules as compared to placebo in subjects with Relapsing Remitting Multiple Sclerosis (RRMS).

NCT ID: NCT00509106 Completed - Bacterial Pneumonia Clinical Trials

Comparative Study of Ceftaroline vs. Ceftriaxone in Adults With Community-Acquired Pneumonia

CAP
Start date: July 2007
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine if the antibiotic ceftaroline is safe and effective in the treatment of community-acquired pneumonia in adults.

NCT ID: NCT00504881 Completed - Epilepsy Clinical Trials

Brivaracetam as add-on Treatment in Adolescents and Adults Suffering From Epilepsy

Start date: October 2007
Phase: Phase 3
Study type: Interventional

This study will compare the safety and efficacy of Brivaracetam at flexible dose with Placebo in subjects suffering from Epilepsy.

NCT ID: NCT00504595 Completed - Clinical trials for Rheumatoid Arthritis

Safety and Efficacy of ACZ885 in Adult Patients With Established Rheumatoid Arthritis

Start date: May 2007
Phase: Phase 2
Study type: Interventional

This study was intended to assess the safety, efficacy, and response to treatment using the American College of Rheumatology (ACR) criteria of 20% improvement in symptoms (ACR20) and to investigate a potential biomarker profile in adult patients with established rheumatoid arthritis

NCT ID: NCT00504556 Completed - Atrial Fibrillation Clinical Trials

A Study to Assess the Safety of a Potential New Drug in Comparison to the Standard Practice of Dosing With Warfarin for Non-valvular Atrial Fibrillation

Start date: June 2007
Phase: Phase 2
Study type: Interventional

This study is to assess the safety of a potential new drug DU-176b for the prevention of stroke/systemic embolic event (SEE) in individuals with non-valvular atrial fibrillation (AF). The duration is 3 months of treatment and a 30 day follow-up visit.

NCT ID: NCT00502801 Completed - Pneumonia Clinical Trials

An Effectiveness, Safety, and Microbiology Study of Doripenem in Patients With Nosocomial (Hospital-acquired) Pneumonia

Start date: August 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effectiveness and safety of doripenem monohydrate in the treatment of patients with nosocomial (hospital-acquired) pneumonia.

NCT ID: NCT00502710 Completed - Clinical trials for Diabetes Mellitus Type 2

A Study of Dipeptidyl-peptidase IV (DPP-IV) RO4876904 in Patients With Type 2 Diabetes.

Start date: July 2007
Phase: Phase 2
Study type: Interventional

This 5 arm study will assess the efficacy, pharmacokinetics, safety and tolerability of a DPP-IV inhibitor compared to placebo in patients with type 2 diabetes. Patients will be randomized to receive DPP-IV(3) at one of 4 doses (of 12.5mg and above), or placebo p.o. Patients receiving metformin before the study will continue on the same dose of metformin. The anticipated time on study treatment is 3-12 months, and the target sample size is 100-500 individuals.