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NCT ID: NCT01058174 Completed - Clinical trials for Liver Transplantation

Liver Transplant European Study Into the Prevention of Fungal Infection

TENPIN
Start date: December 15, 2009
Phase: Phase 3
Study type: Interventional

Prevention of invasive fungal infection in high risk patients following liver transplant.

NCT ID: NCT01057810 Completed - Prostate Cancer Clinical Trials

Phase 3 Study of Immunotherapy to Treat Advanced Prostate Cancer

Start date: May 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if patients with metastatic prostate cancer who have not received chemotherapy live longer when treated with ipilimumab than those treated with a placebo

NCT ID: NCT01056341 Completed - Clinical trials for Infantile Hemangioma

Study to Demonstrate the Efficacy and Safety of Propranolol Oral Solution in Infants With Proliferating Infantile Hemangiomas Requiring Systemic Therapy

Start date: January 2010
Phase: Phase 2/Phase 3
Study type: Interventional

There is an unsatisfied medical need for a first-line treatment of proliferating IHs with a good benefit/risk profile. Based on the recent findings of encouraging results obtained with propranolol in a series of infants with severe Infantile Hemangioma (IH), propranolol is expected to be of significant benefit in the management of the condition. The present study has been designed to confirm efficacy of propranolol in severe IH by demonstrating superiority over placebo and to document the safety profile of propranolol in this indication.

NCT ID: NCT01054885 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Efficacy and Safety Study of Fluticasone Furoate (FF)/GW642444 Inhalation Powder and the Individual Components in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Start date: October 19, 2009
Phase: Phase 3
Study type: Interventional

The Purpose of this study is to assess the efficacy and safety of two strengths of the FF/GW642444 Inhalation Powder in subject with Chronic Obstructive Pulmonary Disease (COPD)

NCT ID: NCT01054170 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Effect on Structural Changes in Airways, Measured by MSCT, of Twice Daily 60mg AZD9668 for 12 Weeks in Chronic Obstructive Pulmonary Disease (COPD) Patients

Start date: January 2010
Phase: Phase 2
Study type: Interventional

The primary objective of the study is to evaluate structural changes effected by AD9668 in the airways of adults with Chronic Obstructive Pulmonary Disease (COPD) by Multi-Slice Computed Tomography (MSCT)

NCT ID: NCT01052194 Completed - Clinical trials for Rheumatoid Arthritis

A 12-week Study of 4 Doses of VX-509 in Subjects With Active Rheumatoid Arthritis

Start date: February 2010
Phase: Phase 2
Study type: Interventional

This study is designed to evaluate safety and assess initial efficacy of VX-509, a JAK3 inhibitor, for treatment of subjects with active RA. This study will assess the clinical response of 4 doses of VX-509 compared to placebo when administered for 12 weeks to patients with active RA. The study will also evaluate the safety and tolerability of VX-509 compared to placebo when administered for 12 weeks to subjects with active RA.

NCT ID: NCT01050998 Completed - Clinical trials for Rheumatoid Arthritis

A Study to Evaluate the Efficacy and Safety of CAM-3001 (Drug) in Subjects With Rheumatoid Arthritis

Start date: January 5, 2010
Phase: Phase 2
Study type: Interventional

The primary objectives of this study is to assess the safety, tolerability and efficacy of multiple doses of the mavrilimumab (CAM-3001) administered subcutaneously in subjects with moderately active Rheumatoid Arthritis (RA).

NCT ID: NCT01050257 Completed - Influenza Clinical Trials

A Study of Intravenously Administered Tamiflu (Oseltamivir) in Patients Over 13 Years of Age With Influenza

Start date: January 2010
Phase: Phase 3
Study type: Interventional

This partially randomized, multi-center parallel-group study will evaluate the safety, pharmacokinetics and the effect on viral load and viral shedding of Tamiflu (Oseltamivir) in patients with influenza. Adult and adolescent patients will be randomized to receive either 100 mg or 200 mg of study drug intravenously every 12 hours. Investigators and patients are blinded to knowledge of the assigned dose of Tamiflu. There is an option to convert to oral Tamiflu after 6 intravenous infusions. The anticipated time on study treatment is 5 days, with an optional treatment extension of a further 5 days, if necessary. There will be a non-randomized, open-label treatment group for patients with moderate/severe renal impairment or renal failure. Intravenous dose levels and frequency will be adjusted appropriately to their renal situation.

NCT ID: NCT01049074 Recruiting - Low Back Pain Clinical Trials

A Random Controlled Test (RCT): Acupuncture Treatment on Nonspecific Low Back Pain (NLBP)

ANLBP
Start date: November 2008
Phase: N/A
Study type: Interventional

Hypothesis: Acupuncture procedure of He's Santong Methods could be an option to treat nonspecific low back pain.

NCT ID: NCT01047319 Terminated - Clinical trials for Relapsing Multiple Sclerosis

A Study to Evaluate the Long-term Safety, Tolerability and Effect of Daily Oral Laquinimod 0.6 mg on Disease Course in Subjects With Relapsing Multiple Sclerosis

Start date: May 27, 2010
Phase: Phase 3
Study type: Interventional

To make laquinimod 0.6 mg available for all subjects who completed the placebo-controlled MS-LAQ-302 study according to the protocol and to evaluate the long-term safety, tolerability and effect on disease course of daily oral laquinimod 0.6 mg in subjects with relapsing multiple sclerosis.