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NCT ID: NCT00125983 Completed - HIV Infections Clinical Trials

Drug Interactions Between Lopinavir/Ritonavir and Oral or Patch Contraceptives in HIV Infected Women

Start date: n/a
Phase: Phase 2
Study type: Interventional

The purpose of this study is to examine the drug interactions between a protease inhibitor (PI)-based regimen including lopinavir/ritonavir (LPV/r) and two forms of contraceptive medications in HIV infected women.

NCT ID: NCT00124449 Completed - Clinical trials for Arthritis, Rheumatoid

Study of Abatacept Versus Placebo to Assess the Prevention of Rheumatoid Arthritis (RA) in Adult Patients

Start date: February 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess if Abatacept given for six months will prevent rheumatoid arthritis (RA) in patients who are at risk for the development of RA in comparison to placebo. High risk patients are defined as those having a positive laboratory test for anti-cyclic citrullinated peptide (anti-CCP2).

NCT ID: NCT00123461 Completed - Renal Failure Clinical Trials

Study of Safety and Efficacy of Doxercalciferol in Patients With Chronic Kidney Disease, Stage 3 or 4, and Secondary Hyperparathyroidism

Start date: July 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to demonstrate the safety and effectiveness of Hectorol® (doxercalciferol) capsules in treating patients with Stage 3 or Stage 4 chronic kidney disease (CKD) with secondary hyperparathyroidism who have vitamin D levels in the normal range. Previous studies with doxercalciferol were conducted in patients who had low levels of vitamin D.

NCT ID: NCT00122863 Completed - Anxiety Disorders Clinical Trials

Duloxetine Compared With Placebo in the Prevention of Relapse in Generalized Anxiety Disorder

Start date: January 2005
Phase: Phase 3
Study type: Interventional

This is a clinical trial assessing the time to relapse of anxiety symptoms among patients with generalized anxiety disorder who have responded to duloxetine therapy.

NCT ID: NCT00122382 Completed - Clinical trials for Rheumatoid Arthritis

Remission and Joint Damage Progression in Early Rheumatoid Arthritis

Start date: July 2005
Phase: Phase 3
Study type: Interventional

This is a world wide study to evaluate the remission and joint damage in subjects treated with abatacept in addition to methotrexate versus subjects who receive methotrexate along with a placebo.

NCT ID: NCT00121667 Completed - Clinical trials for Diabetes Mellitus, Type 2

Study Assessing Saxagliptin Treatment In Type 2 Diabetic Subjects Who Are Not Controlled With Metformin Alone

Start date: August 2005
Phase: Phase 3
Study type: Interventional

The purpose of this clinical research study is to learn whether Saxagliptin added to Metformin therapy is more effective than Metformin alone as a treatment for type 2 diabetic subjects who are not sufficiently controlled with Metformin alone

NCT ID: NCT00121641 Completed - Clinical trials for Diabetes Mellitus, Type 2

Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise

Start date: July 2005
Phase: Phase 3
Study type: Interventional

The purpose of this clinical research study is to learn whether saxagliptin (BMS-477118) is more effective than placebo as a treatment for type 2 diabetic subjects who are not sufficiently controlled with diet and exercise

NCT ID: NCT00120835 Completed - Chronic Hepatitis C Clinical Trials

Valopicitabine When Administered Alone and in Combination With Interferon to Treatment-Naive Patients With Hepatitis C

Start date: July 2004
Phase: Phase 1/Phase 2
Study type: Interventional

This study is being conducted in treatment-naive patients (no previous hepatitis C treatment) to evaluate the safety of valopicitabine (NM283) alone and together with pegylated interferon, a drug approved by the Food and Drug Administration for the treatment of hepatitis C infection. This study is also evaluating the ability of valopicitabine to decrease the amount of hepatitis C virus in the body. The results for patients taking valopicitabine alone will be compared with the results for patients taking valopicitabine together with pegylated interferon.

NCT ID: NCT00119717 Completed - Clinical trials for Cerebrovascular Accident

Safety and Efficacy of NeuroFlo Technology in Ischemic Stroke (SENTIS)

SENTIS
Start date: June 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the safety and efficacy of the NeuroFlo™ catheter for use in patients with ischemic stroke. The NeuroFlo device is intended to increase blood flow to the brain and potentially reduce the damage caused by stroke.

NCT ID: NCT00119678 Completed - Clinical trials for Systemic Lupus Erythematosus

Abatacept in the Treatment and Prevention of Active Systemic Lupus Erythematosus (SLE) Flares in Combination With Prednisone

Start date: September 2005
Phase: Phase 2
Study type: Interventional

The purpose of this clinical research study is to learn whether Abatacept can treat and prevent lupus flares; specifically, in patients with active lupus flares in at least one of three organ systems: skin (discoid lesions); inflammation of the lining of the heart (pericarditis), or inflammation of the lining of the lung (pleuritis/pleurisy); or inflammation of more than 4 joints (arthritis). All participants will receive prednisone or prednisone-equivalent treatment in combination with study medication. The safety of this treatment will also be studied.