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NCT ID: NCT00414661 Completed - Clinical trials for Arthritis, Rheumatoid

Long-Term Safety Follow-Up Of Subjects Previously Enrolled In Rheumatoid Arthritis Studies Of CP-690,550

Start date: April 2007
Phase: N/A
Study type: Observational

The purpose of this study is to follow the health of subjects who have previously been enrolled in studies of CP-690,550 for treatment of their rheumatoid arthritis. Subjects are only eligible for this study after they have completed all participation in other studies of CP-690,550.

NCT ID: NCT00413699 Completed - Clinical trials for Arthritis, Rheumatoid

Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis

Start date: February 5, 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the long-term effectiveness and safety of CP-690,550 for the treatment of rheumatoid arthritis. Subjects are eligible for this study only after participating in another "qualifying" study of CP-690,550 A sub-study will be conducted within the A3921024 study, this study will evaluate the immune response to pneumococcal and influenza vaccines in patients receiving CP-690,550

NCT ID: NCT00412984 Completed - Atrial Fibrillation Clinical Trials

Apixaban for the Prevention of Stroke in Subjects With Atrial Fibrillation

ARISTOTLE
Start date: December 31, 2006
Phase: Phase 3
Study type: Interventional

The trial seeks to determine if apixaban, an investigational anticoagulant (blood-thinner) is as effective as standard therapy (warfarin) in preventing stroke and systemic embolism in subjects with atrial fibrillation and risk factors for stroke.

NCT ID: NCT00411385 Completed - Chronic Hepatitis C Clinical Trials

Efficacy of Albumin Interferon Alfa-2b With Ribavirin Compared to Peg-IFN Alfa-2a With Ribavirin in IFN Naive Patients Geno2/3

Start date: February 2007
Phase: Phase 3
Study type: Interventional

This is a phase 3, randomized, multi-center study to evaluate the efficacy and safety of albumin interferon alfa-2b (alb-IFN)in combination with ribavirin compared with peginterferon alfa-2a (PEGASYS or PEG-IFNa2a) in combination with ribavirin in subjects with chronic hepatitis C, genotype 2/3 who are IFNa treatment naive.

NCT ID: NCT00411099 Completed - Clinical trials for Major Depressive Disorder

Efficacy, Safety and Tolerability of Agomelatine in the Treatment of Major Depressive Disorder

Start date: December 2006
Phase: Phase 3
Study type: Interventional

This study will assess efficacy, safety and tolerability of agomelatine (AGO178) 25 mg and 50 mg in patients with Major Depressive Disorder (MDD). This study includes an 8-week double-blind phase and a 52-week open-label phase.

NCT ID: NCT00410592 Completed - Clinical trials for Gastroesophageal Reflux Disease

Evaluation of 24-Hour Intragastric pH Using Esomeprazole, Lansoprazole, and Pantoprazole in Hispanic Patients With GERD

Start date: October 2006
Phase: Phase 4
Study type: Interventional

This study will be conducted in order to determine safety and efficacy esomeprazole, lansoprazole and pantoprazole control stomach acid by measuring the stomach acid in men and women of Hispanic origin who have GERD.

NCT ID: NCT00410410 Completed - Ulcerative Colitis Clinical Trials

A Study of Abatacept in Patients With Active Ulcerative Colitis

Start date: December 2006
Phase: Phase 3
Study type: Interventional

The purpose of this clinical research study is to learn if abatacept can improve signs and symptoms of active ulcerative colitis in patients who have not had an adequate response to other therapies. The safety of this treatment will also be studied

NCT ID: NCT00410384 Completed - Clinical trials for Systemic Lupus Erythematosus

A Study of Belimumab in Subjects With Systemic Lupus Erythematosus

BLISS-76
Start date: December 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy, safety, tolerability, and impact on quality of life of two different doses of belimumab administered in addition to standard therapy in subjects with active, autoantibody-positive systemic lupus erythematosus (SLE) disease.

NCT ID: NCT00408421 Completed - Clinical trials for Osteoarthritis Knee Pain

Duloxetine Versus Placebo for Osteoarthritis Knee Pain

Start date: November 2006
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to determine if duloxetine reduces pain severity in patients with osteoarthritis knee pain.

NCT ID: NCT00406848 Completed - Clinical trials for Major Depressive Disorder

A Study Comparing the Efficacy and Safety of Duloxetine and Placebo for the Treatment of Depression in Elderly Patients

Start date: November 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the efficacy and safety of duloxetine 60 mg once daily to placebo on depression in elderly patients (greater than or equal to 65 years of age). Patients who do not respond in the first 13 weeks will be eligible for rescue using pre-defined criteria. Patients randomized to duloxetine 60 mg/day meeting the rescue criteria will be increased to 120 mg/day. Patients randomized to the placebo arm meeting the rescue criteria will be assigned to duloxetine 60 mg/day.