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NCT ID: NCT05906628 Active, not recruiting - Hand Eczema Clinical Trials

Topical Ruxolitinib Evaluation in Chronic Hand Eczema

Start date: July 31, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of ruxolitinib cream in adult participants with diagnosis of chronic hand eczema (CHE) and moderate to severe disease activity (Investigator's Global Assessement (IGA) of CHE score 3 or 4).

NCT ID: NCT05905783 Active, not recruiting - Clinical trials for Hidradenitis Suppurativa

Hidradenitis Suppurativa Study of Izokibep

Start date: June 22, 2023
Phase: Phase 3
Study type: Interventional

Izokibep is a small protein molecule that acts as a selective, potent inhibitor of interleukin 17A, to which it binds with high affinity. This study investigates izokibep in subjects with active Hidradenitis Suppurativa (HS), including tumor necrosis factor-alpha inhibitor (TNFi) naïve subjects, and those who had an inadequate response or intolerance to TNFi, or for whom TNFi is contraindicated.

NCT ID: NCT05903300 Active, not recruiting - Clinical trials for Musculoskeletal Pain

Validation of the Polish Version of the MPIIQM Questionnaire for Musicians

Start date: April 17, 2023
Phase:
Study type: Observational

The aim of this study, originally named "Cross-Cultural Adaptation and Validation of the Musculoskeletal Pain Intensity and Interference Questionnaire for Musicians of the Polish Population (MPIIQM-P)" is the enlargement of validation of the Polish questionnaire.

NCT ID: NCT05896527 Active, not recruiting - Plaque Psoriasis Clinical Trials

A Study to Evaluate the Efficacy and Safety of DC-806 in Participants With Moderate to Severe Plaque Psoriasis

Illuminate
Start date: May 11, 2023
Phase: Phase 2
Study type: Interventional

This is a 12-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-ranging study to evaluate the efficacy and safety of DC-806 in participants with moderate to severe plaque psoriasis. This study will evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of multiple oral doses of DC-806 in participants with moderate to severe plaque psoriasis.

NCT ID: NCT05879107 Active, not recruiting - Clinical trials for Respiratory Syncytial Virus Infections

Study to Assess the Immune Response, the Safety and the Reactogenicity of Respiratory Syncytial Virus (RSV) Prefusion Protein 3 Older Adult (OA) (RSVPreF3 OA) Investigational Vaccine When co Administered With PCV20 in Older Adults

Start date: May 26, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the ability of RSVPreF3 OA investigational vaccine to generate an immune response when given in combination with PCV20 and its safety in older adults, aged ≥60 years of age.

NCT ID: NCT05853354 Active, not recruiting - Clinical trials for Osteoporosis, Postmenopausal

Comparative Efficacy, Safety, PK, and Immunogenicity Study

Start date: April 5, 2023
Phase: Phase 3
Study type: Interventional

this comparative clinical study is designed to demonstrate that LY06006 and EU-Prolia have no clinically meaningful differences in clinical efficacy, pharmacodynamic (PD), safety, PK, and immunogenicity in postmenopausal women with osteoporosis.

NCT ID: NCT05829174 Active, not recruiting - Procrastination Clinical Trials

Comparison of Online Group Therapy Interventions for Procrastination

Start date: April 14, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to compare the efficacy of two cognitive behavior therapy (CBT) protocols for procrastination with an active control protocol including cognitive-behavioral elements and with a wait-list control group. The interventions will be delivered online in group settings. All three protocols include identical psychoeducation and cognitive modules related to procrastination, but will differ in the behavioral modules. The behavioral module in one protocol is focused on starting on time and realistic planning. The second protocol implements working time restriction. The active comparator protocol implements the pomodoro time management technique. The wait-list control group will receive one of the CBT protocols after the period of waiting. It is assumed that all active conditions will be superior to the wait-list control, and that CBT protocols will be superior to the protocol including the time management technique. Primary (procrastination) and secondary (depression and anxiety) measures will be collected prior and after the interventions (or waiting period in wait-list group) and after 6-months in the three active condition groups.

NCT ID: NCT05817682 Active, not recruiting - Medical Students Clinical Trials

Interprofessional Education of Medical Students Using Medical Simulation

Start date: October 20, 2022
Phase: N/A
Study type: Interventional

Due to the growing role of medical simulation in the education of medical students and the development of cooperation in interdisciplinary teams in the health care sector, a study was designed to examine the relationship between the competences and resources of students and the role of education through simulation classes based on the development of technical and in cooperation with specialists in these fields. Researchers want to focus on students' levels of stress and anxiety, coping strategies, and self-efficacy. An important element will be the self-assessment of students on the level of their non-technical competences.

NCT ID: NCT05817669 Active, not recruiting - Clinical trials for Primary Sjögren's Syndrome

A Study of the Safety and Effectiveness of Efgartigimod in Patients With Primary Sjögren's Syndrome (pSS)

rho
Start date: April 4, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of human FcRn blocking therapy with efgartigimod compared to placebo, in participants with pSS.

NCT ID: NCT05816395 Active, not recruiting - Clinical trials for Osteoarthritis, Knee

Safety and Efficacy of RHH646 for Knee Osteoarthritis

Start date: May 31, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the articular cartilage-regenerating capacity of RHH646 in the knee as well as to assess safety and tolerability in participants with knee osteoarthritis. The treatment duration will be up to 52 weeks. The total study duration for an individual participant will be up to 62 weeks.