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Hidradenitis Suppurativa clinical trials

View clinical trials related to Hidradenitis Suppurativa.

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NCT ID: NCT03054155 Not yet recruiting - Clinical trials for Hidradenitis Suppurativa

Treatment of Hidradenitis Suppurativa With Eth 755nm Alexandrite Laser

Start date: April 1, 2017
Phase: N/A
Study type: Interventional

Patients with bilateral hidradenitis in the axilla, groin and/or inframammary will be treated on one side with the Alexandrite hair removal laser. The other side will serve as the control.

NCT ID: NCT03049267 Recruiting - Clinical trials for Hidradenitis Suppurativa

Short-term Safety, Efficacy and Mode of Action of Apremilast in Moderate Suppurative Hidradenitis

SMASH
Start date: February 2, 2017
Phase: Phase 2
Study type: Interventional

Study design: A double-blind randomised placebo-controlled trial Intervention: Randomized placebo controlled treatment of 20 HS patients of which fifteen patients will be randomized to apremilast and five patients to placebo. The total duration of the treatment period per subject is 16 weeks. Primary objectives: To evaluate the expression profile of inflammatory cytokines in HS lesional skin at week four (t=4) and week sixteen (t=16): - of patients receiving apremilast compared to placebo; - within both groups relative to baseline (t=0). Secondary objectives: - To prospectively evaluate the clinical efficacy of apremilast. - To assess the effect of apremilast on patient reported outcomes measures. - To assess the short-term safety and tolerability of apremilast in patients with hidradenitis suppurativa.

NCT ID: NCT03040804 Recruiting - Clinical trials for Hidradenitis Suppurativa

Low Dose Radiotherapy for Advanced Hidradenitis Suppurativa

RTHS
Start date: March 1, 2017
Phase: N/A
Study type: Interventional

To establish the safety of radiotherapy in the treatment of advanced hidradenitis suppurativa. Patients will receive radiotherapy treatment over one week and then they will be followed for the next three months.

NCT ID: NCT03001622 Active, not recruiting - Clinical trials for Hidradenitis Suppurativa

Studying Complement Inhibition in Patients With Moderate to Severe Hidradenitis Suppurativa

Start date: December 2016
Phase: Phase 2
Study type: Interventional

The trial enrolls patients with moderate to severe Hidradenitis Suppurativa (HS). The primary goal of the trial is to evaluate the safety and tolerability of IFX-1 administered over 8 weeks in these patients. In addition the trial aims to characterize the pharmacokinetics and pharmacodynamics of IFX-1 as well as to generate preliminary data on the efficacy of IFX-1 on clinical endpoints (e.g., Hidradenitis Suppurativa Clinical Response (HiSCR), Dermatology Life Quality Index (DLQI), Visual Analog Scale (VAS) for disease, VAS for pain, Hidradenitis Suppurativa - Physician's Global Assessment (HS-PGA), Modified Sartorius Score (mSS)).

NCT ID: NCT03001115 Not yet recruiting - Clinical trials for Hidradenitis Suppurativa

Post-Marketing Surveillance of Adalimumab in Korean Hidradenitis Suppurativa Subjects

HS rPMS
Start date: April 2017
Phase: N/A
Study type: Observational

The objective of this study is to evaluate the safety profile of Adalimumab for Hidradenitis Suppurativa (HS) participants in normal medical practice.

NCT ID: NCT02904902 Recruiting - Clinical trials for Hidradenitis Suppurativa

Open-label Study of Adalimumab in Japanese Subjects With Hidradenitis Suppurativa

Start date: September 2016
Phase: Phase 3
Study type: Interventional

This study investigates efficacy, safety and pharmacokinetics of adalimumab in Japanese subjects with moderate to severe Hidradenitis Suppurativa (HS).

NCT ID: NCT02904408 Recruiting - Hidradenitis Clinical Trials

Group Psychotherapy for Patients With Hidradenitis Suppurativa: Effects in Quality of Life

Start date: June 2016
Phase: N/A
Study type: Interventional

The aim of this study is to determine the benefits of group psychotherapy on quality of life for people with hidradenitis suppurativa receiving medical and surgical treatment versus a control group (awaiting group) treated with medical and surgical treatment, without psychotherapy.

NCT ID: NCT02896920 Recruiting - Clinical trials for Hidradenitis Suppurativa (HS)

Canadian Humira Post Marketing Observational Epidemiological Study : Assessing Humira Real-life Effectiveness and Impact on HS Burden of Illness

SOLACE
Start date: September 2016
Phase: N/A
Study type: Observational

This study assesses Humira's® real-life effectiveness in the management of dermatological manifestations of moderate to severe Hidradenitis Suppurativa (HS).

NCT ID: NCT02833909 Completed - Clinical trials for Hidradenitis Suppurativa

Activation of a Cutaneous Inflammasome in the Skin of Hidradenitis Suppurativa Patients

Start date: March 2015
Phase: N/A
Study type: Interventional

The objective is to investigate ex vivo the inflammatory response in hidradenitis suppurativa (HS) (activation of an inflammasome, role of pro-inflammatory cytokines) in the skin of patients treated surgically for this disease. The investigators hypothesize that Th17-derived cytokines, especially Interleukin (IL) IL-17, could serve as a relay in the inflammatory process leading to HS severity and recurrences.

NCT ID: NCT02808975 Recruiting - Clinical trials for Hidradenitis Suppurativa

Safety and Efficacy of Humira (Adalimumab) for Hidradenitis Suppurativa (HS) Peri-Surgically (SHARPS Study)

SHARPS
Start date: July 2016
Phase: Phase 4
Study type: Interventional

The objective of this study is to assess the safety and efficacy of adalimumab prior to surgery in subjects with moderate to severe Hidradenitis Suppurativa (HS) who are surgical candidates.