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Hidradenitis Suppurativa clinical trials

View clinical trials related to Hidradenitis Suppurativa.

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NCT ID: NCT02904902 Recruiting - Clinical trials for Hidradenitis Suppurativa

Open-label Study of Adalimumab in Japanese Subjects With Hidradenitis Suppurativa

Start date: September 2016
Phase: Phase 3
Study type: Interventional

This study investigates efficacy, safety and pharmacokinetics of adalimumab in Japanese subjects with moderate to severe Hidradenitis Suppurativa (HS).

NCT ID: NCT02904408 Recruiting - Hidradenitis Clinical Trials

Group Psychotherapy for Patients With Hidradenitis Suppurativa: Effects in Quality of Life

Start date: June 2016
Phase: N/A
Study type: Interventional

The aim of this study is to determine the benefits of group psychotherapy on quality of life for people with hidradenitis suppurativa receiving medical and surgical treatment versus a control group (awaiting group) treated with medical and surgical treatment, without psychotherapy.

NCT ID: NCT02896920 Recruiting - Clinical trials for Hidradenitis Suppurativa (HS)

Canadian Humira Post Marketing Observational Epidemiological Study : Assessing Humira Real-life Effectiveness and Impact on HS Burden of Illness

SOLACE
Start date: September 2016
Phase: N/A
Study type: Observational

This study assesses Humira's® real-life effectiveness in the management of dermatological manifestations of moderate to severe Hidradenitis Suppurativa (HS).

NCT ID: NCT02833909 Completed - Clinical trials for Hidradenitis Suppurativa

Activation of a Cutaneous Inflammasome in the Skin of Hidradenitis Suppurativa Patients

Start date: March 2015
Phase: N/A
Study type: Interventional

The objective is to investigate ex vivo the inflammatory response in hidradenitis suppurativa (HS) (activation of an inflammasome, role of pro-inflammatory cytokines) in the skin of patients treated surgically for this disease. The investigators hypothesize that Th17-derived cytokines, especially Interleukin (IL) IL-17, could serve as a relay in the inflammatory process leading to HS severity and recurrences.

NCT ID: NCT02808975 Recruiting - Clinical trials for Hidradenitis Suppurativa

Safety and Efficacy of Humira (Adalimumab) for Hidradenitis Suppurativa (HS) Peri-Surgically (SHARPS Study)

SHARPS
Start date: July 2016
Phase: Phase 4
Study type: Interventional

The objective of this study is to assess the safety and efficacy of adalimumab prior to surgery in subjects with moderate to severe Hidradenitis Suppurativa (HS) who are surgical candidates.

NCT ID: NCT02786576 Recruiting - Clinical trials for Hidradenitis Suppurativa

Effectiveness of Adalimumab in Moderate to Severe HidrAdenitis SuppuRativa Patients - a Multi cOuNtry studY in Real Life Setting

HARMONY
Start date: July 2016
Phase: N/A
Study type: Observational

This study will assess the effects of adalimumab treatment in moderate to severe Hidradenitis Suppurativa (HS) patients in the real world setting. The objectives of this study are to estimate the effectiveness of adalimumab treatment on disease severity, to estimate the impact of adalimumab treatment on patients' quality of life, psychological effect, work productivity and healthcare resource utilization and to describe treatment practices over the study period.

NCT ID: NCT02781818 Recruiting - Clinical trials for Hidradenitis Suppurativa

A Randomized Controlled Trial Evaluating the Efficacy of Intralesional Triamcinolone in Hidradenitis Suppurativa.

Start date: June 2016
Phase: N/A
Study type: Interventional

Purpose: To evaluate the effectiveness of intralesional triamcinolone for the treatment of hidradenitis suppurativa Participants: Patients diagnosed with Hidradenitis Suppurativa that have active inflammatory HS lesions. Up to 60 lesions will be treated. Between 20 and 60 patients will be enrolled dependent on the number of lesions they have treated. (up to 3 per patient) Procedures (methods): Injection of triamcinolone or placebo into active lesions of hidradenitis suppurativa

NCT ID: NCT02739828 Recruiting - Clinical trials for Hidradenitis Suppurativa

Post Marketing Observational Study (PMOS) to Assess Quality of Life in Swedish Hidradenitis Suppurativa (HS) Patients

HOPE
Start date: April 2016
Phase: N/A
Study type: Observational

The objective of this study is to assess quality of life (QoL), skin pain, work productivity/activity and health related problems in Swedish patients with moderate to severe HS before and after 6 months treatment with Adalimumab. The patients will be treated in accordance with normal routine clinical care.

NCT ID: NCT02695212 Recruiting - Clinical trials for Hidradenitis Suppurativa

Single Center Study of Apremilast for the Treatment of Hidradenitis Suppurativa

HS
Start date: July 2016
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to evaluate the safety and efficacy of Apremilast in subjects with moderate Hidradenitis Suppurativa (HS).

NCT ID: NCT02643654 Active, not recruiting - Clinical trials for Hidradenitis Suppurativa

MABp1 IN HIDRADENITIS SUPPURATIVA REFRACTORY TO ADALIMUMAB

Start date: December 2015
Phase: Phase 2
Study type: Interventional

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder. Although adalimumab is recently licensed for moderate to severe HS, many cases fail to respond or relapse during treatment. Favorable outcomes from a recently conducted double-blind randomized clinical study on the efficacy of anakinra, one interleukin(IL)-1alpha blocker, in hidradenitis suppurativa (HS), led to validate the efficacy of MABp1, a true human antiIL-1α antibody in these cases.