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NCT ID: NCT00845728 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Exacerbation Study

INVIGORATE
Start date: March 2009
Phase: Phase 3
Study type: Interventional

This study compares indacaterol with tiotropium in terms of bronchodilation over 52 weeks

NCT ID: NCT00841672 Completed - Clinical trials for Moderate to Severe Hypertension

Efficacy and Safety of the Combination of Aliskiren (300 mg) and Amlodipine (10 mg) Compared to Amlodipine (10 mg) Monotherapy in Patients With Moderate to Severe Hypertension

Start date: January 2009
Phase: Phase 3
Study type: Interventional

This study will compare the blood pressure (BP) lowering effect of the combination of aliskiren/amlodipine 300/10 mg versus amlodipine 10 mg monotherapy in patients with moderate to severe hypertension by testing the hypothesis that the combination of aliskiren/amlodipine produces a superior reduction from baseline in mean sitting systolic blood pressure (msSBP) after 8 weeks of treatment.

NCT ID: NCT00839800 Completed - Asthma Clinical Trials

Study to Investigate the Efficacy of Symbicort® SMART.

SAKURA
Start date: February 2009
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to compare the efficacy of Symbicort SMART (Symbicort Turbuhaler 160/4.5μg, one inhalation twice daily plus as needed) with Symbicort Turbuhaler 160/4.5μg, one inhalation twice daily plus terbutaline Turbuhaler 0.4 mg as needed, as asthma therapy

NCT ID: NCT00839527 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Study to Determine the Safety and Efficacy of Albiglutide in Subjects With Type 2 Diabetes

Start date: February 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of albiglutide in subjects with type 2 diabetes

NCT ID: NCT00838903 Completed - Clinical trials for Diabetes Mellitus, Type 2

Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes

Start date: February 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if albiglutide is safe and effective in the treatment of type 2 diabetes.

NCT ID: NCT00831714 Completed - Clinical trials for Venous Thromboembolism

Xarelto for VTE Prophylaxis After Hip or Knee Arthroplasty

XAMOS
Start date: February 2009
Phase: N/A
Study type: Observational

The main goal is to provide additional information to the risk-benefit assessment of the drug.

NCT ID: NCT00829166 Active, not recruiting - Breast Cancer Clinical Trials

An Open-label Study of Trastuzumab Emtansine (T-DM1) vs Capecitabine + Lapatinib in Patients With HER2-positive Locally Advanced or Metastatic Breast Cancer

EMILIA
Start date: February 2009
Phase: Phase 3
Study type: Interventional

This is a Phase III, randomized, multicenter, international, 2-arm, open-label clinical trial designed to compare the safety and efficacy of trastuzumab emtansine (T-DM1) with that of capecitabine + lapatinib for HER2-positive metastatic breast cancer (MBC). Patients were treated until disease progression, unmanageable toxicity, or study termination. Once disease progression was reported, all patients were followed for survival every 3 months until death, loss to follow-up, withdrawal of consent, or study termination.

NCT ID: NCT00821977 Completed - Clinical trials for Diabetes Mellitus, Type 2

Efficacy and Long-Term Safety of Vildagliptin as Monotherapy in Patients With Type 2 Diabetes

Start date: November 2008
Phase: Phase 2/Phase 3
Study type: Interventional

This is a 2-3 period parallel group study with an adaptive element in Type 2 diabetes patients receiving vildagliptin as monotherapy.

NCT ID: NCT00815516 Terminated - Candidiasis Clinical Trials

Study to Compare the Efficacy and Safety of Micafungin Versus Conventional Amphotericin B for the Treatment of Neonatal Candidiasis

MAGIC-2
Start date: February 2013
Phase: Phase 3
Study type: Interventional

The study will evaluate how effective and how safe the drug micafungin is when compared to the drug amphotericin B deoxycholate in treating neonates and young infants with certain fungal infections.

NCT ID: NCT00814307 Completed - Clinical trials for Arthritis, Rheumatoid

A Phase 3 Study Comparing 2 Doses of CP-690,550 vs. Placebo for Treatment of Rheumatoid Arthritis

Start date: February 2009
Phase: Phase 3
Study type: Interventional

This Phase 3 study is intended to provide evidence of the efficacy and safety of CP 690,550 when dosed 5 mg and 10 mg twice a day as monotherapy in adult patients with moderate to severe Rheumatoid Arthritis. It is intended to confirm the benefits of CP-690,550 in improving signs and symptoms and physical function that were observed in the Phase 2 Rheumatoid Arthritis studies.