Clinical Trials Logo

Filter by:
NCT ID: NCT01420653 Completed - Dental Pain Clinical Trials

Maxigesic 325 Acute Dental Pain Study

Start date: April 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether the analgesic effects of Maxigesic USA are greater than acetaminophen, ibuprofen or placebo.

NCT ID: NCT01419873 Completed - Hyperglycaemia Clinical Trials

Study of a Model-based Approach to Blood Glucose Control in Very-low-birthweight Neonates

Start date: August 2008
Phase: Phase 4
Study type: Interventional

Very low birthweight neonates commonly develop high blood sugar levels. There is an association between high blood sugar levels and poorer short term outcomes but it is not known whether the high sugar level itself actually causes the problems. There are a range of ways to manage high sugar levels but there are no consensus guidelines to follow. One option is to manage the high sugar levels with an infusion of insulin. Studies looking at insulin infusions have often used fixed protocols to guide the amount of insulin to be given and are often complicated by hypoglycaemia. This study investigated whether using a model-based approach to individualise insulin administration to neonates with high sugar levels would provide a safe and effective management option for controlling blood sugar levels and avoid the complication of low blood sugar levels.

NCT ID: NCT01410786 Completed - Clinical trials for Osteoarthritis, Knee

Oxford Partial Knee Comparative Instrument Pilot Study

Start date: June 2013
Phase: N/A
Study type: Interventional

The purpose of this prospective clinical data-collection is to document the performance and clinical outcomes of the Oxford Partial Knee System using Signature Custom Guides and Conventional Instrumentation.

NCT ID: NCT01403077 Completed - Clinical trials for Atherosclerosis of Femoral Artery

480 Biomedical Bioresorbable Scaffold System in the Treatment of de Novo Superficial Femoral Artery (SFA) Lesions

STANCE
Start date: October 2011
Phase: N/A
Study type: Interventional

This is an initial evaluation of the 480 Biomedical Bioresorbable Scaffold System for the treatment of subjects with de novo native superficial femoral artery lesions.

NCT ID: NCT01400503 Completed - Clinical trials for Multicentric Castleman's Disease

A Study to Evaluate the Safety of Long-term Treatment With Siltuximab in Patients With Multicentric Castleman's Disease

Start date: April 1, 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the long-term safety of siltuximab in patients with multicentric Castleman's disease (MCD).

NCT ID: NCT01394952 Completed - Clinical trials for Diabetes Mellitus, Type 2

Researching Cardiovascular Events With a Weekly Incretin in Diabetes (REWIND)

REWIND
Start date: July 22, 2011
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to assess whether dulaglutide can reduce major cardiovascular events and other serious outcomes in persons with type 2 diabetes, when added to their anti-hyperglycemic regimen.

NCT ID: NCT01391325 Completed - Gout Clinical Trials

Allopurinol Outcome Study

LASSO
Start date: July 2011
Phase: Phase 4
Study type: Interventional

This is a study of allopurinol in gout patients with hyperuricemia that will evaluate the safety and serum urate (sUA) lowering capability of allopurinol as a urate lowering therapy (ULT) for up to six months. Allopurinol will be dosed according to the local product label, at the discretion of the Investigator, to achieve an optimal, medically appropriate dose for each patient.

NCT ID: NCT01385657 Completed - Atopic Dermatitis Clinical Trials

Safety and Tolerability of Dupilumab in Participants With Moderate to Severe Atopic Dermatitis

Start date: July 31, 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety and tolerability of repeated subcutaneous (SC) doses of Dupilumab in participants with moderate-to-severe atopic dermatitis (AD).

NCT ID: NCT01382953 Completed - Atrial Fibrillation Clinical Trials

The Simple ECG Monitoring Trial (Comparison of a Novel Recording System With a Standard Holter Monitor)

Start date: August 2011
Phase: N/A
Study type: Observational

The purpose of this research is to simplify the standard recording system of the heart rhythm. The investigators desire to improve the ease of monitoring the cardiac rhythm for 24 hours. The investigators intent is to use a very small, innovative monitoring patch system that relieves the patient of wearing a cumbersome and uncomfortable recording system. This research trial will carry the title "The Simple ECG Monitoring" for Comparison of a Sternal ECG Recording System with a Standard ECG Recording System for Holter Monitoring. The data from the investigational device is for comparative purposes only. It will not be used by medical personnel for study subject treatment or diagnostic purposes.

NCT ID: NCT01379534 Completed - Endometrial Cancer Clinical Trials

A Phase II Study to Evaluate the Efficacy of TKI258 for the Treatment of Patients With FGFR2 Mutated or Wild-type Advanced and/or Metastatic Endometrial Cancer

Start date: November 2011
Phase: Phase 2
Study type: Interventional

This is a prospective, multi-center, open-label, single-arm, non-randomized, Phase II study to evaluate the efficacy and safety of TKI258 as second-line therapy in patients with either FGFR2 mutated or wild-type advanced and/or metastatic endometrial cancer.