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NCT ID: NCT00291746 Completed - Clinical trials for Gastroesophageal Reflux

Validation of RDQ Questionnaire

Start date: September 2005
Phase: Phase 4
Study type: Interventional

The primary objective of this study is to determine the accuracy of the Reflux Disease Questionnaire (RDQ) as a diagnostic test for gastroesophageal reflux disease. Symptom evaluation by the RDQ will be compared with other established approaches to the diagnosis of gastroesophageal reflux disease (GERD) in a primary care patient population with symptoms thought to be of upper gastrointestinal (GI) tract origin.

NCT ID: NCT00291330 Completed - Thromboembolism Clinical Trials

Efficacy and Safety of Dabigatran Compared to Warfarin for 6 Month Treatment of Acute Symptomatic Venous Thromboembolism

RE-COVER I
Start date: February 2006
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to determine the comparative safety and efficacy of dabigatran etexilate 150 mg bid administered orally and warfarin as needed (pro re nata - prn) to maintain an International Normalised Ratio (INR) of 2.0-3.0 for 6 month treatment of acute symptomatic venous thromboembolism (VTE), following initial treatment (5-10 days) with a parenteral anticoagulant approved for this indication. This trial aims to demonstrate non-inferiority of dabigatran compared with warfarin in patients with acute symptomatic VTE. After achieving non-inferiority, this trial also aims to establish superiority (by means of hierarchical tests) of dabigatran over warfarin.

NCT ID: NCT00290355 Completed - Clinical trials for Lung Cancer, Non-Small Cell

Study to Test the Efficacy of the Vaccine GSK 249553 in Treating Non-small-cell Lung Cancer After Tumour Removal by Surgery

Start date: May 28, 2002
Phase: Phase 2
Study type: Interventional

Patients will receive injections of GSK 249553 vaccine . Appropriate tests will be performed to assess the safety of the treatment and its ability to induce an immune response.

NCT ID: NCT00290212 Completed - Clinical trials for Perimenopausal Bone Loss

Natto Supplementation to Prevent Loss of Bone Mass in Women Immediately After Menopause

Start date: January 2006
Phase: Phase 2
Study type: Interventional

Study Objective: To determine whether Natto supplementation in women immediately after menopause might prevent severe bone loss Study population: Women 50 - 60 years, 1-5 years after menopause Study Design: Double-blind, placebo-controlled, randomized controlled trial. A "phase II" clinical trial. Instruments Used to Measure Therapeutic Response: Lunar Prodigy DEXA bone densitometer Study Treatment Group: Daily supplementation with Vitamin K2, "NATTO" Study Control Group: Identically-looking placebo medication Duration of treatment: 12 months Duration of Subject Participation in Study: 12 months Assessment of Therapeutic response: Given an expected reduction of bone mass density of - 1.1% annually in the placebo group, the minimum clinically significant difference between the groups is 0.3 percentage points. The trial is therefore powered to detect a reduction in annual bone mass loss of 0.3 percentage points in the treatment group. Numbers of Evaluable Subjects Required: 304 Maximum # Subjects 334

NCT ID: NCT00290095 Completed - Multiple Myeloma Clinical Trials

Quality of Life in Patients With Multiple Myeloma

Start date: January 2006
Phase: N/A
Study type: Observational

The purpose of this study is to determine Clinically important difference and Response shift in quality of life in patients with Multiple Myeloma.

NCT ID: NCT00289627 Completed - Melanoma Clinical Trials

A Single Arm Study of Ipilimumab Monotherapy in Patients With Previously Treated Unresectable Stage III or IV Melanoma

Start date: April 2006
Phase: Phase 2
Study type: Interventional

The purpose of this clinical research study is to evaluate the Best Overall Response Rate (BORR), (as per modified WHO criteria) in patients with previously treated melanoma-Stage III (unresectable) or Stage IV melanoma receiving 10 mg/kg of ipilimumab. The safety of this product will also be evaluated.

NCT ID: NCT00289432 Completed - Breast Cancer Clinical Trials

Hospital Based Group Intervention for Breast Cancer Patients.

Start date: April 2006
Phase: N/A
Study type: Interventional

INCAM-study is a multicenter, prospective, randomized controlled trial. The aim of the study is to test the effectiveness of psychoeducative intervention when offered in hospital setting as a component of routine breast cancer care. The hypotheses are; - that breast cancer patients participating in psychoeducative interventions focusing on coping will experience better health-related quality of life than those who participate in the hospital standardised psychoeducative intervention. - that coping styles are associated with the immune system.

NCT ID: NCT00287144 Withdrawn - Hypothyroidism Clinical Trials

Post Partum Thyroiditis 2: Long Term Observations

Start date: January 2014
Phase:
Study type: Observational

The study tries to determine if post partum thyroiditis has marked long term (20 years after partum) risk for developing hypothyroidism.

NCT ID: NCT00286299 Completed - Schizophrenia Clinical Trials

Treatment Effects From Aerobic Endurance Training and Maximal Strength Training in Patients Suffering From Schizophrenia

Start date: October 2005
Phase: N/A
Study type: Interventional

This study investigates treatment effects from aerobic endurance training, maximal strength training and computer game on aerobic capacity, work efficiency and psychiatric symptoms in patients suffering from schizophrenia. The study is a controlled trial. The aim is to describe the population in respect to aerobic capacity and muscular strength. Low aerobic capacity and muscular strength are important risk factors for cardiovascular disease (CVD). The study also aim to evaluate physical and psychiatric effects from physical training. Effects from participation in physical training or computer game on symptoms, depression and quality of life will be investigated. Data will be collected between October 2005 and August 2007.

NCT ID: NCT00284492 Completed - Menopause Clinical Trials

Acupuncture for Hot Flushes in Menopause

ACUFLASH
Start date: February 2006
Phase: N/A
Study type: Interventional

In a pragmatic study investigate whether Traditional Chinese Medicine acupuncture-care decreases the frequency of hot flushes and increases health related quality of life among postmenopausal women. The intervention group will receive 10 sessions of acupuncture, the control group will engage in self care only. The study period lasts for 12 weeks.