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NCT ID: NCT01076621 Completed - Menopause Clinical Trials

Observational Study to Investigate the Occurrence of Bleeding in Postmenopausal Women Treated With Estradiol/NETA for 12 Months

Start date: May 2010
Phase: N/A
Study type: Observational

This study is conducted in Europe. The primary aim of this observational study is to investigate the occurrence of bleeding in women taking 0.5 mg estradiol and 0.1 mg norethisterone acetate (NETA) for 12 months.

NCT ID: NCT01075178 Completed - Clinical trials for Severe Respiratory Syncytial Virus Infection

Retrospective Palivizumab Study in Children With Hemodynamically Significant Congenital Heart Disease

Start date: July 2006
Phase: N/A
Study type: Observational

Retrospective medical record review study of specific adverse events in children with congenital heart disease who received palivizumab for prophylaxis of serious respiratory syncytial virus infection and control subjects that did not receive palivizumab

NCT ID: NCT01074892 Completed - Clinical trials for Endometrial Hyperplasia

A Study Comparing Mirena and Systemic Progestin for Endometrial Hyperplasia

Mirena
Start date: May 2005
Phase: Phase 4
Study type: Interventional

Randomized controlled multi-center study with three arms including 200 patients with low risk endometrial hyperplasia. After confirmed diagnosis the patients will receive one of the following treatments: 1. Provera (Medroxyprogesterone (MPA)/progestin) 10 mg per oral treatment for 6 months 10 day each cycle, 2. MPA 10 mg continuously for 6 months, 3. Mirena (Levonorgestrel) impregnated IUD for 6 months.

NCT ID: NCT01074827 Completed - Multiple Sclerosis Clinical Trials

Improving Gait in Multiple Sclerosis (MS) - Strength Training or Treadmill Walking?

Start date: March 2010
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the effect of strength training for the lower extremities and treadmill training on walking ability in persons with Multiple Sclerosis. The study is a randomized control trial with two groups and the intervention is 8 weeks of intensive strength training or treadmill walking. Primary outcome measure is walking ability, secondary outcome measures are balance, work economy and strength.

NCT ID: NCT01074697 Completed - Nausea Clinical Trials

Efficacy of Two Antiemetic Regimens in Patients Receiving Radiotherapy and Concomitant Weekly Cisplatin

GAND-emesis
Start date: April 2010
Phase: Phase 3
Study type: Interventional

GAND-emesis is a multinational, randomized, double-blind, placebo-controlled, parallel-group study to investigate the efficacy and tolerability of a neurokinin1 receptor antagonist (fosaprepitant dimeglumine) in combination with an antiemetic (anti-nausea-and-vomiting) control regimen (palonosetron and dexamethasone) in patients with a gynaecological cancer diagnosis, who are scheduled to receive radiotherapy and weekly chemotherapy. The study aims at investigating if a three-drug antiemetic regimen is superior to a two-drug regimen (standard treatment) in preventing nausea and vomiting in patients receiving radiotherapy and weekly chemotherapy. A pilot study demonstrated that approximately 50% of patients will experience nausea and vomiting when offered a two-drug antiemetic regimen, and it is expected that addition of a third drug (a neurokinin1 receptor antagonist) can increase the proportion of patients with no vomiting in the course of combined chemo-radiotherapy.

NCT ID: NCT01074671 Completed - Clinical trials for Mitral Valve Insufficiency

CG Future® Annuloplasty Ring/Band Clinical Trial

Start date: June 2009
Phase: Phase 4
Study type: Interventional

The primary goal of the study is to document the number of patients that are successfully implanted and benefit from the implantation of both a CG Future Annuloplasty ring or a band.

NCT ID: NCT01074580 Terminated - Crohn's Disease Clinical Trials

Contrast Enhanced Ultrasonography (CEUS) of Patients With Crohn's Disease

Start date: November 2009
Phase: N/A
Study type: Observational

The purpose of this study is investigate if high frequency sonography and contrast enhanced sonography can be used to predict remission in patients with deterioration of Crohn's disease treated with steroids or tumor necrosis factor (TNF) alfa inhibitors.

NCT ID: NCT01072825 Recruiting - Clinical trials for Physical and Psychological Evaluation of Hormonal Therapy in Transsexual Persons

A European Network for the Investigation of Gender Incongruence

ENIGI
Start date: February 15, 2010
Phase:
Study type: Observational

The physical and psychological effects of the hormonal treatment of transsexual persons are not sufficiently described. 'Transparency' wants to answer this question in a prospective manner, in a multicenter study to describe these effects. The low prevalence of transsexualism was the stimulus to search for European partners for this Protocol. A common standardized hormonal protocol was designed.

NCT ID: NCT01071148 Completed - Infertility Clinical Trials

A Phase IV, Prospective, Observational, Open Label, Single Centre Cohort Trial to be Conducted in Norway During One Year to Assess the Cumulative Pregnancy Rate in a New Series of In-vitro Fertilization (IVF) Treatment Cycles Following Three or More Previous IVF Treatment Cycles Without Live Birth

Start date: June 2009
Phase: N/A
Study type: Observational

The primary objective of this observational study is to assess the cumulative rate of ongoing pregnancy at 10 ±2 weeks after hCG administration in a new series of IVF-treatment cycles in a total of 176 subjects, who have undergone three or more previous IVF-treatment cycles without live birth. Secondary objectives include subgroup analysis on the effect of age on the likelihood of pregnancy at 10 ±2 weeks after hCG administration in a new series of IVF-treatment cycles in patients < 35 years and ≥ 35 years, who have undergone three or more previous IVF-treatment cycles without live birth. The information obtained from this trial will be helpful for subjects who are considering further IVF treatments and for IVF centres, as well as for the formulation of governmental policies regarding healthcare reimbursement in Norway.

NCT ID: NCT01070485 Completed - Breast Cancer Clinical Trials

BAY88-8223, Alpharadin, Breast Cancer Patients With Bone Dominant Disease

Start date: January 2010
Phase: Phase 2
Study type: Interventional

The purpose of the study is to investigate if multiple (up to four) intravenous injections of Xofigo (Alpharadin) have any clinically relevant effect on bone markers in breast cancer patients with bone dominant disease who have progressed on endocrine therapy and are no longer considered suitable for endocrine therapy. In addition the safety of Xofigo (Alpharadin) will be assessed.