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NCT ID: NCT03471104 Withdrawn - Clinical trials for Diabetes Mellitus, Type 1

The Diabetes Patient-Reported Outcome Measures Trial

DiaPROM
Start date: January 15, 2018
Phase: N/A
Study type: Interventional

The study aim to evaluate the use of Patient-Reported Outcome Measures in clinical diabetes consultations.

NCT ID: NCT03470922 Active, not recruiting - Melanoma Clinical Trials

A Study of Relatlimab Plus Nivolumab Versus Nivolumab Alone in Participants With Advanced Melanoma

RELATIVITY-047
Start date: April 11, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine whether relatlimab in combination with nivolumab is more effective than nivolumab by itself in treating unresectable melanoma or melanoma that has spread.

NCT ID: NCT03469791 Active, not recruiting - Clinical trials for Degenerative Lumbar Spondylolisthesis

Degenerative Spondylolisthesis; Micro-decompression vs Decompression + Instrumented Fusion; Long Term Follow up

DS-registry
Start date: September 1, 2007
Phase: N/A
Study type: Interventional

In many countries a majority of patients with degenerative spondylolisthesis are operated on with decompression plus instrumented fusion, but the scientific evidence for adding fusion is controversial. To evaluate whether micro-decompression alone is as good as (non-inferior to) decompression plus instrumented fusion, a study with data from the Norwegian Registry for Spine Surgery was conducted, now the long-term follow up.

NCT ID: NCT03466541 Active, not recruiting - Alcohol Consumption Clinical Trials

Workplace Interventions Preventing Risky Use of Alcohol and Sick Leave

WIRUS
Start date: August 2013
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effectiveness of two workplace interventions (the Riskbruk model and Balance) in reducing risky alcohol consumption, sickness absence and presenteeism. The purpose is to assess whether the Riskbruk model should be implemented in the Norwegian workforce in its entirety, whether the less extensive and costly alternative Balance is sufficient, or if neither one of them show effectiveness compared to usual care.

NCT ID: NCT03462290 Completed - Facial Pain Clinical Trials

Botox Injections for Patients With Persistent Facial Pain

Start date: May 1, 2018
Phase: Phase 2
Study type: Interventional

The main objective of this study is to investigate efficacy and safety of injecting botulinum toxin towards the sphenopalatine ganglion using MultiGuide in patients with persistent idiopathic facial pain

NCT ID: NCT03460379 Recruiting - Obesity, Morbid Clinical Trials

Bariatric Surgery and Pharmacokinetics of Escitalopram

Start date: November 2, 2016
Phase:
Study type: Observational

Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines. These factors are potentially influenced by bariatric surgery. Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological availability of medication. In this study the pharmacokinetic effects of bariatric surgery on escitalopram are investigated.

NCT ID: NCT03460366 Recruiting - Obesity, Morbid Clinical Trials

Bariatric Surgery and Pharmacokinetics of Enalapril

Start date: November 2, 2016
Phase:
Study type: Observational

Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines. These factors are potentially influenced by bariatric surgery. Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological availability of medication. In this study the pharmacokinetic effects of bariatric surgery on enalapril are investigated.

NCT ID: NCT03460353 Recruiting - Obesity, Morbid Clinical Trials

Bariatric Surgery and Pharmacokinetics of Dexamphetamine

Start date: November 2, 2016
Phase:
Study type: Observational

Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines. These factors are potentially influenced by bariatric surgery. Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological availability of medication. In this study the pharmacokinetic effects of bariatric surgery on dexamphetamine are investigated.

NCT ID: NCT03460327 Recruiting - Obesity, Morbid Clinical Trials

Bariatric Surgery and Pharmacokinetics of Candesartan

Start date: November 2, 2016
Phase:
Study type: Observational

Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines. These factors are potentially influenced by bariatric surgery. Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological availability of medication. In this study the pharmacokinetic effects of bariatric surgery on candesartan are investigated.

NCT ID: NCT03460314 Recruiting - Obesity, Morbid Clinical Trials

Bariatric Surgery and Pharmacokinetics of Buprenorphine

Start date: November 2, 2016
Phase:
Study type: Observational

Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines. These factors are potentially influenced by bariatric surgery. Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological availability of medication. In this study the pharmacokinetic effects of bariatric surgery on buprenorphine are investigated.