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NCT ID: NCT00599417 Completed - Clinical trials for Respiratory Tract Infections

PulmonarOM (Bacterial Lysates) in Respiratory Tract Infections

Start date: December 2007
Phase: Phase 4
Study type: Interventional

Primary - To evaluate the efficacy of Pulmonaron in the decrease of interleukin-4/interferon gamma after second period of treatment Secondary - To evaluate the efficacy of Pulmonarom in the prevention of upper respiratory tract infections symptoms through patient evaluation of fever or respiratory presence after second period of treatment - To evaluate loss of working or study days after second period of treatment - To evaluate the safety and tolerability of Pulmonarom in the population under study

NCT ID: NCT00599339 Completed - Clinical trials for Idiopathic Parkinson Disease

Transdermal Rotigotine User Surveillance Study

TRUST
Start date: June 2006
Phase:
Study type: Observational

This study will be conducted in an observational multiple-cohort design aimed at acquiring clinical, treatment, health status, and economic data. Patients with Parkinson's disease (PD) will be enrolled.

NCT ID: NCT00596752 Completed - Clinical trials for Peripheral Arterial Occlusive Disease

Alprostadil in Peripheral Arterial Occlusive Disease (PAOD) Stage IV

ESPECIAL
Start date: March 2004
Phase: Phase 4
Study type: Interventional

The study is to confirmatorily show a superior effect of Alprostadil compared to placebo on the rate of complete healing of ischemic necroses and ulcerations as well as on the frequency and height of major amputations in patients suffering from PAOD stage IV.

NCT ID: NCT00595205 Completed - Rotavirus Vaccines Clinical Trials

Intussusception Surveillance After Rotarix Introduction in Mexico

Start date: January 2008
Phase: N/A
Study type: Observational

GSK Biologicals' rotavirus vaccine, Rotarix™ has been recommended for universal use targeting infants through the Expanded Program on Immunization (EPI) in Mexico. This protocol describes a Phase IV safety study in Mexico designed to further evaluate the safety profile of Rotarix™ with regard to intussusception (IS). The data generated by this study will be useful for public health officers and policy makers in confirming the safety profile of Rotarix™.

NCT ID: NCT00594204 Completed - Smoking Cessation Clinical Trials

Assessment of Safety and Efficacy of Varenicline in Patients That Wish to Stop Smoking

Start date: April 2008
Phase: Phase 4
Study type: Interventional

The primary objective of this protocol is to evaluate 12 weeks of treatment of varenicline compared to placebo for smoking cessation. Abstinence from cigarette smoking and other tobacco products (e.g., pipe, cigars, chew, snuff.) use during non-treatment follow-up period will also be evaluated.

NCT ID: NCT00591578 Completed - Hypertension Clinical Trials

Efficacy and Safety Comparison of Azilsartan Medoxomil to Valsartan in Participants With Essential Hypertension

Start date: December 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy and safety of TAK-491 (azilsartan medoxomil), once daily (QD), to valsartan in participants with essential hypertension.

NCT ID: NCT00591201 Completed - Clinical trials for Spondylarthropathies

Efficacy, Safety, and Tolerability Study of Infliximab in Juvenile Spondyloarthropathies

Start date: June 2002
Phase: Phase 2/Phase 3
Study type: Interventional

Tumor necrosis factor (TNF) alpha is a pro-inflammatory cytokine playing a significant role in the pathogenesis of the spondyloarthropathies (SpA). Infliximab is a TNF alpha blocking monoclonal antibody efficacious and safe as treatment of adult-onset SpA. In this study we will try to demonstrate that infliximab administered at 5mg/kg to patients with juvenile onset SpA over a period of 12 weeks will have more efficacy than placebo and that it will be well tolerated. At the end of this phase, patients will go into a 52-week open extension to demonstrate sustained efficacy, safety, and tolerability of infliximab We will include 34 patients with juvenile onset SpA unresponsive to standard treatment. Efficacy will be assessed by counting the number of actively inflamed joints and a number of other parameters.

NCT ID: NCT00589693 Terminated - Clinical trials for Ventilator-Associated Pneumonia

To Compare Safety and Efficacy of Doripenem Versus Imipenem-Cilastatin in Patients With Ventilator-Associated Pneumonia

Start date: April 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to show that doripenem is as effective as imipenem-cilastatin in the treatment of patients with ventilator-associated pneumonia.

NCT ID: NCT00580216 Terminated - Atrial Fibrillation Clinical Trials

Evaluation of Weekly Subcutaneous Biotinylated Idraparinux Versus Oral Adjusted-dose Warfarin to Prevent Stroke and Systemic Thromboembolic Events in Patients With Atrial Fibrillation

BOREALIS-AF
Start date: December 2007
Phase: Phase 3
Study type: Interventional

The objective is to evaluate whether once weekly subcutaneous (SC) injection of idrabiotaparinux is at least as efficient to prevent clots in brain and in the other organs than oral international normalized ratio (INR) adjusted-dose warfarin in patients with atrial fibrillation (AF).

NCT ID: NCT00579306 Completed - Stroke Clinical Trials

Levels of Inflammatory Markers in the Treatment of Stroke—An SPS3 Ancillary Study

LIMITS
Start date: June 2005
Phase: N/A
Study type: Observational

The goals of this trial are to determine the prognostic significance of an elevated level of inflammatory blood markers in people who have experienced small subcortical strokes and who are enrolled in the Secondary Prevention of Small Subcortical Strokes (SPS3) trial.