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NCT ID: NCT03370289 Completed - Clinical trials for Pandemic Influenza Prevention

A Phase 4 Post-marketing Study of Intramuscular Injections of BLB-750 in Healthy Adult Subjects

Start date: January 12, 2018
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the immunogenicity and safety of two intramuscular vaccinations with BLB-750 in healthy Japanese adults.

NCT ID: NCT03370133 Completed - Psoriatic Arthritis Clinical Trials

A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Placebo and an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

BE VIVID
Start date: December 6, 2017
Phase: Phase 3
Study type: Interventional

This is a study to compare the efficacy of bimekizumab versus placebo and an active comparator in the treatment of subjects with moderate to severe chronic plaque psoriasis (PSO).

NCT ID: NCT03369704 Completed - Clinical trials for Seasonal Allergic Rhinitis

Study of Efficacy and Safety of Omalizumab in Severe Japanese Cedar Pollinosis Adult and Adolescent Patients

Start date: December 15, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study was to demonstrate the efficacy and safety of omalizumab compared with placebo, on top of SoC (anti-histamine and nasal corticosteroid) in adult and adolescent patients with severe Japanese cedar pollinosis, whose symptoms were inadequately controlled despite the current recommended therapies (nasal corticosteroids plus one or more medications out of anti-histamine, leukotriene receptor antagonist, or prostaglandin D2/thromboxane A2 receptor antagonist) in the previous 2 Japanese cedar pollen seasons.

NCT ID: NCT03366818 Completed - Clinical trials for Acute Ischemic Stroke

New Stent Retriever, VERSI System for AIS

Start date: September 21, 2017
Phase: N/A
Study type: Interventional

To confirm efficacy and safety of VERSI system for acute ischemic stroke

NCT ID: NCT03366428 Completed - Clinical trials for Malignant Neoplasm of Breast

Phase 1 Study to Evaluate the Effect of DS-8201a on the QT/QTc Interval and Pharmacokinetics in HER2-Expressing Breast Cancer

Start date: December 26, 2017
Phase: Phase 1
Study type: Interventional

This study will look at the effect on the QTc interval and pharmacokinetics after multiple dosing in subjects with HER2-expressing metastatic and/or unresectable breast cancer.

NCT ID: NCT03364751 Completed - Clinical trials for Periodontal Diseases

Effect of Switching From Cigarette Smoking to the Use of IQOS on Periodontitis Treatment Outcome

Start date: November 7, 2017
Phase: N/A
Study type: Interventional

The purpose of this study was to demonstrate in patients with generalized chronic periodontitis that switching from cigarette smoking to using IQOS improves the response to periodontal therapy and the overall oral health status compared to continuing cigarette smoking. Note: "IQOS" is the Tobacco Heating System (THS) with Marlboro Heatsticks, marketed in Japan under the brand name IQOS

NCT ID: NCT03364244 Completed - Clinical trials for Pulmonary Arterial Hypertension

Revatio Special Investigation for Long-term Use in Pediatric Patients

Start date: November 30, 2017
Phase:
Study type: Observational

Secondary data collection study: safety and effectiveness of Revatio in pediatric patients under Japanese medical practice

NCT ID: NCT03361956 Completed - Hepatitis B Clinical Trials

An Efficacy, Safety, and Pharmacokinetics Study of JNJ-56136379 in Participants With Chronic Hepatitis B Virus Infection

Start date: February 13, 2018
Phase: Phase 2
Study type: Interventional

The main purpose of this study is to evaluate efficacy of 24 weeks of study treatment, in terms of changes in hepatitis B surface antigen (HBsAg) levels.

NCT ID: NCT03361865 Completed - Clinical trials for UC (Urothelial Cancer)

Pembrolizumab in Combination With Epacadostat or Placebo in Cisplatin-ineligible Urothelial Carcinoma (KEYNOTE-672/ECHO-307)

Start date: December 4, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the efficacy and safety of pembrolizumab + epacadostat vs pembrolizumab + placebo in participants with cisplatin-ineligible urothelial carcinoma.

NCT ID: NCT03361748 Completed - Multiple Myeloma Clinical Trials

Efficacy and Safety Study of bb2121 in Subjects With Relapsed and Refractory Multiple Myeloma

KarMMa
Start date: December 18, 2017
Phase: Phase 2
Study type: Interventional

This is an open label, single-arm, multicenter, Phase 2 study to evaluate the efficacy and safety of bb2121 in subjects with relapsed and refractory multiple myeloma. A leukapheresis procedure will be performed to manufacture bb2121 chimeric antigen receptor (CAR) modified T cells. Prior to bb2121 infusion subjects will receive lymphodepleting therapy with fludarabine and cyclophosphamide.