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NCT ID: NCT00641615 Completed - Colorectal Cancer Clinical Trials

Peptide Vaccine and S-1/CPT-11 Therapy for Patients With Unresectable Advanced Colorectal Cancer

Start date: May 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and immune response of different doses of RNF43-721 emulsified with Montanide ISA 51 in combination with S-1/CPT-11 chemotherapy.

NCT ID: NCT00641043 Completed - Clinical trials for Diabetes Mellitus, Type 2

Efficacy vs Placebo as Initial Combination Therapy With Pioglitazone

Start date: March 2008
Phase: Phase 3
Study type: Interventional

The objective of the current study is to investigate the efficacy, safety and tolerability of BI 1356 (Linagliptin) (5 mg / once daily) compared to placebo given for 24 weeks as initial combination therapy with pioglitazone 30 mg in patients with type 2 diabetes mellitus with insufficient glycaemic control.

NCT ID: NCT00640510 Completed - Schizophrenia Clinical Trials

A Study Comparing Rapid Acting Intramuscular Olanzapine and Placebo in Agitated Patients With Schizophrenia

Start date: March 2008
Phase: Phase 3
Study type: Interventional

The primary objectives of the study is to confirm if the efficacy of IM olanzapine in patients with schizophrenia is greater than IM placebo by comparing changes from baseline to 2 hours post first IM injection of agitation.

NCT ID: NCT00639925 Active, not recruiting - Pancreatic Cancer Clinical Trials

Antiangiogenic Peptide Vaccine Therapy With Gemcitabine in Treating Patient With Pancreatic Cancer

Start date: March 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, and tolerability of HLA-A*2402 restricted epitope peptide VEGFR1 and VEGFR2 emulsified with Montanide ISA 51 in combination with gemcitabine

NCT ID: NCT00639353 Terminated - Myopia Clinical Trials

Silicone Hydrogel Contact Lenses on Low Astigmatism in Japan

Start date: February 2008
Phase: N/A
Study type: Interventional

This study seeks to evaluate the clinical performance of a recently released contact lens designed to correct astigmatism to an established contact lens that has historically been used in these patients.

NCT ID: NCT00639327 Completed - Gastric Cancer Clinical Trials

Second Line Chemotherapy for S-1 Refractory Advanced Gastric Cancer

Start date: March 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is compare overall survival of the test arm (CPT-11/S-1 combination) to the control arm (CPT-11 alone) in the subjects with S-1 refractory advanced gastric cancer.

NCT ID: NCT00639314 Completed - Pancreatic Cancer Clinical Trials

Trial on the Evaluation of Pylorus-ring in Pancreaticoduodenectomy

Start date: October 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to clarify whether resecting pylorus-ring decreases delayed gastric emptying after pancreaticoduodenectomy and improves postoperative quality of life (QOL).

NCT ID: NCT00638859 Completed - Pneumonia Clinical Trials

Japanese Study Evaluating the Effects of Telithromycin in Children With Community-Acquired Pneumonia

Start date: March 2004
Phase: Phase 3
Study type: Interventional

The primary objective is to assess the safety of telithromycin (HMR3647) 20 mg/kg qd for 5-7 days in children with community-acquired pneumonia (CAP). Secondary objectives are to assess Pharmacokinetics, Efficacy and Acceptability of telithromycin 20 mg/kg qd for 5-7 days in children with CAP.

NCT ID: NCT00638534 Completed - Otitis Media Clinical Trials

Japanese Study Evaluating the Effects of Telithromycin in Children With Acute Otitis Media

Start date: February 2004
Phase: Phase 3
Study type: Interventional

The primary objective is to assess the safety of telithromycin (HMR3647) 20 mg/kg qd for 5 days in children with acute otitis media (AOM). Secondary objectives are to assess Efficacy, Pharmacokinetics and Acceptability of telithromycin 20 mg/kg qd for 5 days in children with AOM.

NCT ID: NCT00638495 Completed - Clinical trials for Pruritus With Chronic Liver Disease

Phase II Study of TRK-820 Soft Capsules — Intractable Pruritus in Patients With Chronic Liver Disease —

Start date: March 2008
Phase: Phase 2
Study type: Interventional

The efficacy and safety of TRK-820 are to be evaluated in the treatment of intractable pruritus in patients with Chronic Liver Disease by administering 2.5, 5 and 10 microg of this drug or placebo for 28 days in four groups with a design of randomized, double-blind, parallel-group comparison. In addition, the plasma concentrations of TRK-820 and its primary metabolites are to be determined.