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NCT ID: NCT01102400 Completed - Clinical trials for Advanced Solid Malignancies

A Study of MEDI-575 in Patients With Advanced Solid Malignancies

Start date: March 2010
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability of MEDI-575 in Japanese patients with advanced solid tumors (dose escalation part) and hepatocellular carcinoma (expansion part).

NCT ID: NCT01101451 Active, not recruiting - Clinical trials for Cervical Adenocarcinoma

Radiation Therapy With or Without Chemotherapy in Patients With Stage I-IIA Cervical Cancer Who Previously Underwent Surgery

Start date: April 12, 2010
Phase: Phase 3
Study type: Interventional

This randomized phase III trial studies radiation therapy with chemotherapy to see how well they work compared to radiation therapy alone in treating patients with stage I-IIA cervical cancer who previously underwent surgery. Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether giving radiation therapy together with chemotherapy is more effective than radiation therapy alone in treating patients with cervical cancer.

NCT ID: NCT01100307 Completed - Macular Edema Clinical Trials

A Phase 3 Study To Compare The Efficacy And Safety Of 0.3 MG Pegaptanib Sodium To Sham Injections In Subjects With Diabetic Macular Edema

Start date: May 2010
Phase: Phase 3
Study type: Interventional

The purpose of the study to assess the efficacy of pegaptanib sodium 0.3 mg comparing sham injection and to confirm safety of pegaptanib sodium 0.3 mg in subjects with diabetic macular edema.

NCT ID: NCT01099839 Completed - Healthy Volunteers Clinical Trials

A Study to Assess Drug-Drug Interaction Between ASP1941 and Miglitol

Start date: February 2010
Phase: Phase 1
Study type: Interventional

This study is to assess the pharmacokinetic interaction between ASP1941 and Miglitol in healthy volunteers.

NCT ID: NCT01099046 Recruiting - Stress Clinical Trials

Stress Management Therapy for Meniere's Disease

SMT
Start date: January 2009
Phase: N/A
Study type: Interventional

Attacks in Meniere's disease, characterized by vertigo and hearing loss, are well known to occur repeatedly under stressed environment. Hitherto, its pathology was revealed to be inner ear hydrops through human temporal bone studies in 1938. For the pathogenesis of inner ear hydrops resulting in Meniere's attacks, plasma vasopressin elevation due to stress and V2 receptor overexpression in the inner ear could be essential as a basis of this disease. In the present study, we'd like to find the effective and feasible way to reduce plasma vasopressin level in patients with Meniere's disease.

NCT ID: NCT01098786 Completed - Clinical trials for Swine-Origin Influenza A H1N1 Virus

Drug Use Investigation for Cell-culture Derived Influenza A (H1N1) Emulsion HA Vaccine

Start date: February 2010
Phase: N/A
Study type: Observational

This is to evaluate safety of cell-derived A/H1N1 influenza HA vaccine in healthy Japanese subjects.

NCT ID: NCT01098461 Completed - Clinical trials for Diabetes Mellitus, Type 2

Dose Ranging Study of Albiglutide in Japanese Subjects

Start date: April 2010
Phase: Phase 2
Study type: Interventional

This is a randomized, double-blind, placebo-controlled, multicenter, 4-parallel-group, dose ranging study evaluating the dose response, efficacy and safety of subcutaneously injected GSK716155 (albiglutide) in Japanese subjects with type 2 diabetes mellitus.

NCT ID: NCT01097681 Completed - Clinical trials for Type 2 Diabetes Mellitus

A Study to Assess the Pharmacokinetics, Pharmacodynamics of ASP1941 in Diabetes Mellitus Patients With Renal Impairment

Start date: February 16, 2010
Phase: Phase 1
Study type: Interventional

The primary objective of this study is to compare the pharmacokinetics of ASP1941 in type 2 diabetes mellitus patients with normal renal function and those with mild or moderate renal impairment.

NCT ID: NCT01097005 Completed - Clinical trials for Mycobacterium Infections, Atypical

Special Investigation of Clarith/Klaricid in Patients With Non-tuberculous Mycobacterial Pulmonary Infections

Start date: January 2009
Phase:
Study type: Observational

To evaluate the efficacy and safety of long-term treatment with clarithromycin in patients with Non-tuberculous Mycobacterial Pulmonary Infections.

NCT ID: NCT01096433 Completed - Sleep Apnea Clinical Trials

Circadian Variations of Prostaglandin in Sleep Apnea

Start date: May 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the associations of circadian variations, sleep architecture, hypertension and prostanoids in the patients with sleep apnea. In addition, the patients introduced to continuous positive airway pressure(CPAP) treatment, the effects of CPAP are also evaluated.