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NCT ID: NCT01724177 Completed - Clinical trials for Adult T-Cell Leukemia-Lymphoma

A Phase 2 Study of Lenalidomide in Patients With Relapsed or Recurrent Adult T-cell Leukemia-lymphoma

Start date: November 12, 2012
Phase: Phase 2
Study type: Interventional

To evaluate the efficacy of lenalidomide in patients with Adult T-cell Leukemia-lymphoma (ATL) who have previously received chemotherapy for ATL.

NCT ID: NCT01722825 Completed - Neoplasms Clinical Trials

Study of LY2157299 in Japanese Participants With Cancer

Start date: November 2012
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to evaluate the safety and side effects of LY2157299 in Japanese participants with advanced cancer or cancer that has spread to other parts of the body.

NCT ID: NCT01721876 Completed - Clinical trials for Leukemia, Myeloid, Acute

Volasertib in Combination With Low-dose Cytarabine in Patients Aged 65 Years and Above With Previously Untreated Acute Myeloid Leukaemia, Who Are Ineligible for Intensive Remission Induction Therapy (POLO-AML-2)

Start date: January 29, 2013
Phase: Phase 3
Study type: Interventional

To investigate the efficacy, safety, and pharmacokinetics of intravenous volasertib + subcutaneous low dose cytarabine in patients >= 65 years of age with previously untreated acute myeloid leukaemia, ineligible for intensive remission induction therapy

NCT ID: NCT01721096 Completed - Clinical trials for Coronary Artery Disease

XIENCE PRIME Japan Post-Marketing Surveillance (PMS)

Start date: October 2012
Phase:
Study type: Observational

The objectives of the PMS are to observe the frequency, type, and degree of device deficiency to assure the safety of the new medical device (XIENCE PRIME) as well as to collect information on evaluation of the efficacy and safety for reevaluation.

NCT ID: NCT01721057 Completed - Clinical trials for Rheumatoid Arthritis

A Study in Moderate to Severe Rheumatoid Arthritis Participants

RA-BUILD
Start date: December 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether baricitinib 4 milligram (mg) once daily (QD) is superior to placebo in the treatment of participants with moderately to severely active Rheumatoid Arthritis (RA) who have had inadequate response to or are intolerant to at least 1 conventional disease-modifying antirheumatic drug (cDMARD)(cDMARD-IR [inadequate response] participants) and who have not received a biologic disease-modifying antirheumatic drug (DMARD).

NCT ID: NCT01721044 Completed - Clinical trials for Rheumatoid Arthritis

A Moderate to Severe Rheumatoid Arthritis Study

RA-BEACON
Start date: January 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether baricitinib 4 milligram (mg) once daily is superior to placebo in the treatment of participants with moderately to severely active Rheumatoid Arthritis (RA) who have had an inadequate response to a tumor necrosis factor (TNF) inhibitor, despite ongoing treatment with conventional disease-modifying antirheumatic drugs (cDMARDs).

NCT ID: NCT01719380 Completed - Colorectal Cancer Clinical Trials

Study of LGX818 and Cetuximab or LGX818, BYL719, and Cetuximab in BRAF Mutant Metastatic Colorectal Cancer

Start date: November 23, 2012
Phase: Phase 2
Study type: Interventional

This study will assess the safety and efficacy of LGX818 when combined with cetuximab or combined with cetuximab and BYL719 in patients with BRAF mutant metastatic colorectal cancer

NCT ID: NCT01719055 Recruiting - Pain Clinical Trials

RELIEF - A Global Registry to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain

RELIEF
Start date: November 19, 2012
Phase:
Study type: Observational

To compile characteristics of real-world clinical outcomes for Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice, when used according to the applicable Directions for Use - and - To evaluate the economic value and technical performance of Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice

NCT ID: NCT01718691 Completed - Clinical trials for Mantle Cell Lymphoma Where Hematopoietic Stem Cell Transplantation is Not Indicated

Efficacy and Safety Study of SyB L-0501 in Combination With Rituximab in Patients With Untreated, Low-grade B Cell Non-Hodgkin's Lymphoma and Mantle Cell Lymphoma

Start date: n/a
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of SyB L-0501 (two-day consecutive 90 mg/m2/day IV drip infusions) in combination with rituximab (375 mg/m2 IV drip infusion) on untreated, low-grade B cell non-Hodgkin's lymphoma and mantle cell lymphoma where hematopoietic stem cell transplantation is not indicated.

NCT ID: NCT01718158 Completed - Hepatitis C Clinical Trials

Efficacy and Safety Evaluation of a Regimen Consisting of Peginterferon Lambda-1a + Ribavirin + Daclatasvir (Lambda + RBV + DCV) in HCV Genotype 1b Treatment naïve Patients or Prior Relapsers to Peginterferon Alfa + Ribavirin (Alfa + RBV) Therapy

STRUCTURE
Start date: January 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if treatment with Pegylated Interferon Lambda-1a, given in combination with Ribavirin and Daclatasvir for 24 weeks, is as safe and effective as the standard treatment with Pegylated Interferon Alfa-2a + Ribavirin + Telaprevir in subjects who are infected with Chronic Hepatitis C virus genotype 1b and have never received any prior anti-HCV treatment, or who have relapsed after an initial, successful treatment with Pegylated Interferon Alfa + Ribavirin