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NCT ID: NCT02607306 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Japanese Subjects With Type 2 Diabetes Mellitus.

DUALâ„¢ I Japan
Start date: November 18, 2015
Phase: Phase 3
Study type: Interventional

This trial is conducted in Asia. The aim of this trial is to compare the efficacy and safety of insulin degludec/liraglutide, insulin degludec and liraglutide in Japanese subjects with type 2 diabetes mellitus.

NCT ID: NCT02607280 Completed - Clinical trials for Diabetic Peripheral Neuropathic Pain

DS-5565 Phase III Study for Renal Impairment in Japanese Subjects

Start date: December 2015
Phase: Phase 3
Study type: Interventional

Investigate the safety and efficacy of DS-5565 in Japanese subjects with Diabetic Peripheral Neuropathic Pain (DPNP) with renal impairment or Post-Herpetic Neuralgia (PHN) with renal impairment.

NCT ID: NCT02605447 Completed - Clinical trials for Coronary Artery Disease

EVOLVE Short DAPT Study

Start date: February 16, 2016
Phase: Phase 4
Study type: Interventional

The EVOLVE Short DAPT Study is a prospective, multicenter, single-arm study designed to assess the safety of 3-month DAPT in subjects at high risk for bleeding undergoing PCI with a SYNERGY Stent System.

NCT ID: NCT02605057 Completed - Psoriasis Vulgaris Clinical Trials

Dermatopharmacokinetic Trial of LEO 80185 Gel

Start date: November 2015
Phase: Phase 1
Study type: Interventional

Given that LEO 80185 gel takes effect in the upper layer of the skin, it is important to compare and examine the amount of the drug in the upper layer of the skin with that of Dovobet® Ointment. Therefore, a dermatopharmacokinetic study will be conducted in healty adult male volunteers to evaluate pharmacokinetics of LEO 80185 gel and Dovobet® Ointment in the stratum corneum. In this trial, a single application of LEO 80185 gel and Dovobet® ointment will be applied to multiple test sites on the back of healthy Japanese male adults and the trial is designed to compare the amount of each of the active ingredients at steady state or close-to-steady state between LEO 80185 gel and Dovobet® Ointment. The amount of calcipotriol and betamethasone dipropionate in the stratum corneum will be assessed by use of tape stripping.

NCT ID: NCT02603497 Completed - Clinical trials for Patients With Impaired Renal Function

Pharmacokinetics Study in Patients With Impaired Renal Function and Subjects With Normal Renal Function

Start date: November 24, 2015
Phase: Phase 1
Study type: Interventional

The objective of this study is to compare the pharmacokinetics of ASP015K in patients with impaired renal function and subjects with normal renal function.

NCT ID: NCT02603432 Completed - Urothelial Cancer Clinical Trials

A Study Of Avelumab In Patients With Locally Advanced Or Metastatic Urothelial Cancer (JAVELIN Bladder 100)

Start date: April 25, 2016
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to compare maintenance treatment with avelumab plus best supportive care (BSC) with BSC alone, to determine if avelumab has an effect on survival in patients with locally advanced or metastatic urothelial cancer that did not worsen during or following completion of first-line chemotherapy.

NCT ID: NCT02601001 Completed - Healthy Volunteer Clinical Trials

Pharmacokinetics and Safety Study of Omecamtiv Mecarbil in Healthy Japanese Adults

Start date: November 13, 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetics (PK), safety, and tolerability of omecamtiv mecarbil in healthy volunteers in Japan.

NCT ID: NCT02600455 Completed - Clinical trials for Rheumatoid Arthritis

Use-Results Survey for ORENCIA® Subcutaneous Injection 125mg Syringe 1mL

Start date: September 2013
Phase: N/A
Study type: Observational

The purpose of this study to collect information on the safety, especially localized injection site reactions, and efficacy of ORENCIA Subcutaneous Injection 125mg Syringe 1mL in patients with rheumatoid arthritis.

NCT ID: NCT02598570 Completed - Lymphoma Clinical Trials

Study Evaluating Duvelisib in Japanese Subjects With Relapsed or Refractory Lymphoma

Start date: November 2015
Phase: Phase 1
Study type: Interventional

This study seeks to evaluate the safety and pharmacokinetics of duvelisib in Japanese participants with relapsed or refractory lymphoma.

NCT ID: NCT02598310 Terminated - Breast Cancer Clinical Trials

Neoadjuvant Nab-PTX and Trastuzumab for ER Negative and HER2 Positive Breast Cancer

Start date: November 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of nab-PTX and trastuzumab for ER negative and HER2 positive operable (tumor size of 3cm or less and N0) breast cancer.