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NCT ID: NCT00099242 Completed - Alzheimer's Disease Clinical Trials

Efficacy and Safety of the Rivastigmine Transdermal Patch in Patients With Probable Alzheimer's Disease

Start date: November 2003
Phase: Phase 3
Study type: Interventional

The goal of this research study is to evaluate the safety and efficacy of the rivastigmine transdermal patch in patients with probable Alzheimer's Disease.

NCT ID: NCT00097357 Completed - Pulmonary Embolism Clinical Trials

BMS-562247 in Subjects Undergoing Elective Total Knee Replacement Surgery

Start date: October 2004
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to learn if BMS-562247 can prevent blood clots in the legs and lungs in men and women following unilateral total knee replacement surgery. The safety of this treatment will also be studied.

NCT ID: NCT00096811 No longer available - Hepatitis B Clinical Trials

Entecavir for Subjects With Chronic Hepatitis B Infection: An Early Access Program

Start date: September 2003
Phase: N/A
Study type: Expanded Access

The purpose of this clinical research study is to provide entecavir to subjects with chronic Hepatitis B infection who have failed or who have demonstrated intolerance of marketed therapies or for those in whom use of these agents is contraindicated and that have no other available treatment options.

NCT ID: NCT00095394 Completed - Hypertension Clinical Trials

Irbesartan/Hydrochlorothiazide (HCTZ) Combination Therapy as First Line Treatment for Severe Hypertension

Start date: September 2004
Phase: Phase 3
Study type: Interventional

The purpose of this clinical research is to learn if severe hypertension can be better controlled by initially treating with a combination of drugs (Irbesartan/HCTZ), in patients who are unlikely to achieve blood pressure (B/P) control with only one drug. In addition, the study will also evaluate the safety and tolerability of the drugs.

NCT ID: NCT00095290 Completed - Albuminuria Clinical Trials

Irbesartan Versus Placebo in Combination With Ramipril for Treatment of Albuminuria

Start date: September 2004
Phase: Phase 4
Study type: Interventional

Albumin in the urine is usually a signal that you might be at risk of cardiovascular complications. The purpose of this study is to determine if the albumin in your urine can be decreased by the treatment regimen that consists of irbesartan taken at the same time with ramipril.

NCT ID: NCT00094458 Completed - Crohn Disease Clinical Trials

Trial Comparing Infliximab and Infliximab and Azathioprine in the Treatment of Patients With Crohn's Disease na�ve to Both Immunomodulators and Biologic Therapy (Study of Biologic and Immunomodulator Naive Patients in Chrohn's Disease: SONIC

Start date: March 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the safety and effectiveness of three different treatments for patients with Crohns disease who have not responded to previous treatment with a group of drugs commonly used to treat Crohn's Disease (5-ASA) and corticosteroids. Patients will receive either infliximab (a drug used to treat autoimmune diseases) or azathioprine (an immunosuppressant or drug used to suppress the immune system) or a combination of both for up to 34 weeks. This research study will involve approximately 500 patients. The main study involves up to 34 weeks (approximately 8 months). A study extension of an additional 20 weeks (approximately 5 months) is optional for patients who successfully complete the main study. A country-specific study extension of open label infliximab treatment for an additional 1 year is optional for patients who successfully complete the main study extension.

NCT ID: NCT00094029 Approved for marketing - Clinical trials for Gastrointestinal Neoplasm

A Treatment Protocol for Patients With Gastrointestinal Stromal Tumor (GIST) Who May Derive Benefit From Treatment With SU011248

Start date: September 2004
Phase: N/A
Study type: Expanded Access

The purpose of this study is to permit access to SU011248 for treatment use by patients with GIST given the following conditions: a) patients undergo screening, but are not eligible for participation in ongoing clinical studies such as A6181004; AND b) patients have GIST which standard treatments have not been able to control with acceptable toxicity AND c) patients have the potential to derive clinical benefit from treatment with SU011248.

NCT ID: NCT00093470 Completed - Clinical trials for Recurrent Adult Acute Myeloid Leukemia

Tipifarnib in Treating Patients With Acute Myeloid Leukemia in Remission

Start date: August 18, 2004
Phase: Phase 3
Study type: Interventional

This randomized phase III trial studies tipifarnib in treating patients with acute myeloid leukemia (AML) in remission. Tipifarnib may stop the growth of cancer cells by blocking the enzymes necessary for their growth. It is not yet known whether tipifarnib is more effective than observation alone in preventing the recurrence of AML.

NCT ID: NCT00093093 Completed - Chronic Hepatitis C Clinical Trials

Study of Viramidine to Ribavirin in Patients With Chronic Hepatitis C Who Are Treatment Naive

VISER2
Start date: June 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the safety and effectiveness of viramidine to ribavirin in chronic hepatitis C patients who have never before received treatment.

NCT ID: NCT00091949 Completed - Stroke Clinical Trials

Insulin Resistance Intervention After Stroke Trial

IRIS
Start date: February 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if pioglitazone is effective in preventing future strokes or heart attacks among non-diabetic persons who have had a recent ischemic stroke.