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NCT ID: NCT00616954 Terminated - Clinical trials for Graft Versus Host Disease

A Study to Evaluate the Effect of ATG-F on Engraftment, Graft Versus Host Disease (GVHD) and Graft Versus Leukemia (GVL) Effect in Haplo-identical SCT

Start date: May 2008
Phase: Phase 3
Study type: Interventional

This study is planned to evaluated whether ATG is needed in haploidentical stem cell transplantation

NCT ID: NCT00616876 Completed - Sepsis Clinical Trials

Lactulose Supplementation in Premature Infants

Start date: February 2005
Phase: Phase 2
Study type: Interventional

A pilot study to test the safety of use of lactulose in preterm infants and to preliminary assess the hypothesis that lactulose would support the early growth of Lactobacilli in the stools of premature infants and possibly would also improve nutritional status and decrease NEC and late-onset sepsis.

NCT ID: NCT00616460 Completed - Clinical trials for Hematologic Diseases

ACRIPAB- Trial: Anti Coagulation Regimen In High Risk PAtients for Bleeding

ACRIPAB
Start date: February 2008
Phase: Phase 3
Study type: Interventional

To determine the safety/efficacy of Bivallirudin Vs unfractionated heparin (UFH) on top of dual antiplatelet therapy in patients with high tendency for bleeding during urgent and elective PCI.

NCT ID: NCT00616382 Not yet recruiting - Clinical trials for Patent Ductus Arteriosus

Treating the Resistant Patent Ductus Arteriosus (PDA)

Start date: March 2008
Phase: Phase 2
Study type: Interventional

Persistent postnatal ductal patency may have significant adverse hemodynamic effects, frequently necessitating therapeutic intervention in order to facilitate ductal closure. Medical therapy for patency of the ductus arteriosus is successful mediating ductal closure in approximately 70% of treated infants. In a recent study in our population, 17% of the babies showed no ductal response to the first course of treatment and 9.4% of our study infants eventually underwent surgical ligation of the ductus after failure of medical therapeutic closure.We propose to evaluate and compare two alternate therapeutic approaches to ductal closure in babies who do not respond to initial therapy.

NCT ID: NCT00615940 Completed - Clinical trials for Metastatic Breast Cancer

Combination of Oral WX-671 Plus Capecitabine vs. Capecitabine Monotherapy in First-line Her2-negative Metastatic Breast Cancer

Start date: July 2008
Phase: Phase 2
Study type: Interventional

This randomized, double-blind, placebo controlled phase II trial is studying how well capecitabine works when given in combination with WX-671 or when given alone in treating patients receiving first-line therapy for her2negative metastatic breast cancer.

NCT ID: NCT00615550 Completed - Preterm Delivery Clinical Trials

PREGNANT Short Cervix Trial

Start date: March 2008
Phase: Phase 3
Study type: Interventional

The purpose of this research study is to evaluate the usefulness of progesterone vaginal gel in decreasing the preterm birth rate in a population of pregnant women with short cervical length and at high risk for preterm birth.

NCT ID: NCT00615264 Completed - Type 1 Diabetes Clinical Trials

Efficacy Study of DiaPep277 in Newly Diagnosed Type 1 Diabetes Patients

DIA-AID
Start date: September 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if DiaPep277 can effectively protect the internal production of insulin in patients newly diagnosed with type 1 diabetes, by stopping the immune destruction of insulin-producing beta-cells in the pancreas. DiaPep277 acts on the immune system and is expected to prevent further destruction of the beta-cells by stimulating regulatory responses, without causing immunological suppression.

NCT ID: NCT00612898 Terminated - HIV Infections Clinical Trials

Study of the Efficacy and Safety of Apricitabine, a New NRTI, to Treat Drug-resistant HIV Infection

Start date: February 2008
Phase: Phase 2/Phase 3
Study type: Interventional

Apricitabine is a new NRTI which is active against drug-resistant HIV. NRTIs are often included as part of patients' treatment, but many HIV-infected patients develop resistance to commonly used NRTIs such as lamivudine (3TC) and emtricitabine (FTC). This study will examine whether including apricitabine as part of patients' treatment is more effective than including lamivudine,when patients change treatment because of drug resistance.

NCT ID: NCT00611390 Completed - Viral Tracheitis Clinical Trials

Treatment of Acute Tracheitis and Laryngitis With Essential Oils of Aromatic Plants

Start date: January 2008
Phase: Phase 1/Phase 2
Study type: Interventional

This randomized, double blind, parallel group study, compared the efficacy of spray containing aromatic essential oils of some herbal plants, against placebo in the treatment of patients with acute viral Laryngitis or Tracheitis. Study objectives: Primary to demonstrate a hoarseness or cough relief within 20 minutes after first administration of treatment with the spray. Secondary to demonstrate a reduction of a defined symptoms sum score based on symptoms and signs comparing baseline therapy from the beginning to the end of 3 days treatment

NCT ID: NCT00610779 Completed - Rhino-Sinusitis Clinical Trials

Treatment of Acute Rhino-Sinusitis With Essential Oils of Aromatic Plants

Start date: January 2008
Phase: Phase 1/Phase 2
Study type: Interventional

This randomized, double blind, parallel group study, compared the efficacy of spray containing aromatic essential oils of some herbal plants, against placebo in the treatment of patients with acute Rhino-sinusitis. Study objectives: Primary to demonstrate a relief in the nasal obstruction within 20 minutes after first administration of treatment with the spray. Secondary to demonstrate a reduction of a defined symptoms sum score based on symptoms and signs comparing baseline therapy from the beginning to the end of 3 days treatment