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NCT ID: NCT00883402 Recruiting - Carotid Stenosis Clinical Trials

Carotid Endarterectomy Versus Carotid Artery Stenting in Asymptomatic Patients

ACST-2
Start date: January 2008
Phase: N/A
Study type: Interventional

The trial randomise patients with asymptomatic carotid artery narrowing in whom prompt physical intervention is thought to be needed, but there there is still substantial uncertainty shared by patient and doctor about whether surgery or stenting is the more appropriate choice. The study is looking at immediate risks (within one month)and at long term benefits

NCT ID: NCT00883194 Completed - Pain Clinical Trials

A Safety and Effectiveness Pilot Study of PRF-108 and PRF-110 in Healthy Volunteers

Start date: October 2010
Phase: Phase 1/Phase 2
Study type: Interventional

This is a clinical study testing PRF-108 and PRF-110 (a new extended release 4% gel formulations of ropivacaine) in an experimentally induced pain model in healthy volunteers. PRF-108 and PRF-110 are designed to deliver slow release of ropivacaine over 72 hours.

NCT ID: NCT00882999 Completed - Clinical trials for Relapsing-Remitting Multiple Sclerosis

A Study of Participants With Relapsing-Remitting Multiple Sclerosis (RRMS)

Start date: April 2009
Phase: Phase 2
Study type: Interventional

To look at the ability of LY2127399 to reduce magnetic resonance imaging (MRI) lesions at 12, 16, 20, and 24 weeks compared to placebo.

NCT ID: NCT00882453 Completed - Multiple Sclerosis Clinical Trials

Physical Activity and Fatigue in Early Multiple Sclerosis (MS)

BEGIN
Start date: August 2006
Phase: N/A
Study type: Observational

The purpose of this observational study is to obtain a survey on physical activity in patients who for the first time have experienced symptoms which indicate a high risk for developing multiple sclerosis (MS) and in patients with recently diagnosed MS, and to obtain information on factors potentially influencing the patients' level of activity.

NCT ID: NCT00881140 Completed - Uterine Fibroid Clinical Trials

Efficacy Study of Vaginal Mifepristone to Treat Uterine Fibroids

Start date: April 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effect of daily dosage of vaginally mifepristone on reduction of uterine fibroids size and the symptoms associated with uterine fibroids.

NCT ID: NCT00879333 Completed - Clinical trials for Advanced Gastric Cancer

Safety and Efficacy of RAD001 (Everolimus) Monotherapy Plus Best Supportive Care in Patients With Advanced Gastric Cancer (AGC)

GRANITE-1
Start date: July 2009
Phase: Phase 3
Study type: Interventional

This study is designed to assess the safety and efficacy of RAD001 monotherapy in patients with advanced gastric cancer which has progressed after one or two lines of prior chemotherapy.

NCT ID: NCT00878709 Completed - Breast Cancer Clinical Trials

Study Evaluating The Effects Of Neratinib After Adjuvant Trastuzumab In Women With Early Stage Breast Cancer

ExteNET
Start date: July 9, 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate whether neratinib can further reduce the risk of recurrence from previously diagnosed HER-2 positive breast cancer after adjuvant treatment with trastuzumab.

NCT ID: NCT00878358 Completed - Osteoarthritis Clinical Trials

Hydrotherapy Versus Physiotherapy for Short-term Rehabilitation After Primary TKR

Start date: June 2009
Phase: N/A
Study type: Interventional

Primary objective: To compare the effects of short term therapy post total knee replacement (TKR) between a hydrotherapy treatment group and a physiotherapy treatment group. Secondary objectives: To compare the effects of short term therapy post total knee replacement (TKR) between a hydrotherapy treatment group and a physiotherapy treatment group based on measurements of timed up and go (TUG, as primary outcome), range of motion, pain and quality of life.

NCT ID: NCT00878332 Active, not recruiting - Dental Implants Clinical Trials

Histologic Evaluation of Bone Formation After Alveolar Augmentation by "Sandwich Osteotomy" Procedure for Dental Implants Insertion

Start date: February 2009
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate histologic bone remodeling after interpositional bone graft ("sandwich osteotomy" technique) using xenograft to fill the gap of the bone after moving and fixation it in the proper place.

NCT ID: NCT00878241 Completed - Colorectal Surgery Clinical Trials

Compression Anastomosis Using the CAR™ 27

Start date: June 2008
Phase: N/A
Study type: Interventional

Purpose: Evaluation of the CAR™ 27 for the creation of compression anastomoses. Indication: Compression Anastomosis Ring (CAR™ 27) device for creation of circular anastomoses during colonic or colorectal resection. Study Design: Prospective, open labeled study. Patient Population: Male or female subjects 18 years of age or older who are scheduled for non emergency laparoscopic or open colonic or colorectal resections. A temporary loop ileostomy/colostomy can be preformed up to the discretion of the surgeon. No. of Subjects: 15 patients estimated up to three months to enroll. Duration of Treatment: During the operation - creation of the anastomosis. Duration of Follow-up: Follow-up evaluation will be performed daily while hospitalized, during a post-op clinic visit at approximately 1 month (30 days ± 5 days) including a proctoscopic exam and by phone after 3 months. Endpoints: To evaluate the creation of a safe and functioning anastomosis and the occurrence of adverse events related to the use of the CAR™ 27 device.