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NCT ID: NCT01243242 Completed - ADHD Clinical Trials

Clinical Efficacy & Safety, of Metadoxine (MG01CI) Extended Release in Attention-Deficit Hyperactivity Disorder (ADHD)

Start date: February 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate efficacy, safety and tolerability of metadoxine (MG01CI) extended release formulation for the treatment of adults diagnosed with ADHD

NCT ID: NCT01242800 Completed - Breast Cancer Clinical Trials

Early Surgery or Standard Palliative Therapy in Treating Patients With Stage IV Breast Cancer

Start date: May 16, 2011
Phase: N/A
Study type: Interventional

RATIONALE: The primary tumor might be a source of re-seeding of distant sites and therefore elimination of this source of metastasizing cells by early local therapy may be of benefit. PURPOSE: This randomized phase III trial is studying early surgery to see how well it works compared to standard palliative therapy in treating patients with stage IV breast cancer.

NCT ID: NCT01242761 Not yet recruiting - Rotator Cuff Tear Clinical Trials

Ultrasound as a Diagnostic Tool for Rotator Cuff Tears

Start date: January 2011
Phase: N/A
Study type: Observational

After comparing ultrasound study of rotator cuff injuries that have been evaluated both in the community and in a hospital-based ultrasound service with actual surgical findings, it is expected that specialist performed imaging and evaluation will be most accurate and that those performed in the community will be not accurate enough.

NCT ID: NCT01242514 Terminated - Clinical trials for Rheumatoid Arthritis

Evaluation of Long-term Safety and Effectiveness of Fostamatinib in the Treatment of Rheumatoid Arthritis (RA)

OSKIRA-X
Start date: January 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the long term safety and tolerability of fostamatinib in patients with rheumatoid arthritis (RA).

NCT ID: NCT01242293 Completed - Labor Stage, Second Clinical Trials

Intrapartum Hydration

Start date: November 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to determine that maternal hydration during labor with fluids containing glucose at a rate of 125 ml per hour does not affect the duration of labor compared to Ringer Lactate at a rate of 250 ml per hour.

NCT ID: NCT01242137 Recruiting - Diabetes Clinical Trials

Pharmacogenetic Effect on the Pharmacodynamics of Glibenclamide

Start date: October 2009
Phase: N/A
Study type: Observational

Glibenclamide is metabolized by the hepatic enzyme P450 CYP2C9 to less active form. Polymorphism of this enzyme demonstrated clinical significance when examined on other drugs from the sulfonylurea drug family, to whom Glibenclamide is included. The investigators assumption is that patients with less active alleles of the enzyme may show lower dose requirements of the drug for glycemic control, when compared to patients homozygotes to wild-type alleles.

NCT ID: NCT01241851 Not yet recruiting - Clinical trials for Cognitive Function in Elderly

Effect of Acute Exercise on Cognitive Functions

Start date: January 2011
Phase: Phase 0
Study type: Interventional

To determine whether acute aerobic exercise versus resistance exercise effects cognitive function among older adults.

NCT ID: NCT01241591 Completed - Psoriasis Clinical Trials

A Phase 3, Multi Site, Randomized, Double Blind, Placebo Controlled Study Of The Efficacy And Safety Comparing CP- 690,550 And Etanercept In Subjects With Moderate To Severe Chronic Plaque Psoriasis

Start date: November 2010
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy of CP-690,550 as compared to etanercept and the safety of CP-690,550 for treatment of moderate to severe chronic plaque psoriasis.

NCT ID: NCT01241396 Completed - Multiple Myeloma Clinical Trials

A Study to Record in an Observational Manner the Treatment of Multiple Myeloma as it is Being Done in Every Day Practice Without Providing Any Investigational Drug or Prescribing Any Procedure

Start date: October 2010
Phase: Phase 4
Study type: Observational

The primary objective of this observational study is to document and describe current treatment regimens and disease progression of patients with Multiple Myeloma (MMY). The aim of this registry is to provide accurate, descriptive information on the way Multiple Myeloma is treated in routine clinical practice. The registry will collect information related to the treatment received for Multiple Myeloma. About 3000 patients will take part in the study in about 28 countries. The registry will only collect information that is already in medical files regarding treatment. Patients will not be required to actively do anything in addition to what would be done without participating in this registry, nor will there be any procedures or interventions that are not already part of the current treatment.

NCT ID: NCT01239797 Completed - Multiple Myeloma Clinical Trials

Phase III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Relapsed or Refractory Multiple Myeloma

ELOQUENT - 2
Start date: June 20, 2011
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine whether the addition of Elotuzumab to Lenalidomide/low-dose Dexamethasone will increase the progression free survival (PFS).