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NCT ID: NCT02978365 Completed - Clinical trials for Chronic Instability of Joint

Factors Associated With Full Recovery After Surgical Repair of Shoulder Instability

Start date: March 16, 2017
Phase: N/A
Study type: Interventional

Case control study to evaluate different factors (e.g muscle strength, psychological factors) that are associated with full recovery and functional status 6 months after surgical repair of shoulder instability.

NCT ID: NCT02977091 Recruiting - Fitness Clinical Trials

Fitness Level in Short Stature Children and After Growth Hormone Treatment

Start date: December 15, 2016
Phase:
Study type: Observational

fitness and Physical activity will be evaluate in short stature children, using the Euro Fitness testing and the Wingate anaerobic test. the fitness level will be evaluate in healthy short children and with growth hormone deficiency at base line and after 6 month .

NCT ID: NCT02976779 Completed - Clinical trials for Safety Study for Future Treatment of Psoriasis

A Phase I, Double Blind, Randomized, Placebo Controlled, Maximal Dose Study to Determine the Safety, Tolerability of Topical Cream Containing MGC (Medical Grade Cannabis) in Healthy Volunteers

Start date: February 3, 2017
Phase: Phase 1
Study type: Interventional

This single center, prospective, double-blind, placebo-controlled, randomized two parts study (part I and part II) will assess the safety of topical cream (3% CBD and 3% THC), applied twice daily (bid), in healthy subjects, for up to 6 treatment weeks and additional 2 follow-up weeks.

NCT ID: NCT02976571 Recruiting - Clinical trials for Postoperative Complications

Local and Intraperitoneal Analgetics in Gynecologic Laparoscopy for Post Operative Pain Relief

Start date: November 2016
Phase: N/A
Study type: Interventional

A comparison between local and intraperitoneal analgetics to placebo, during laparoscopy, regarding post operative pain.

NCT ID: NCT02976467 Completed - Clinical trials for Myocardial Infarction

A Double-blind Study to Investigate Efficacy, Safety and Tolerability of BAY 1142524 in Patients After Acute Myocardial Infarction With Left-ventricular Dysfunction

CHIARA MIA 2
Start date: December 30, 2016
Phase: Phase 2
Study type: Interventional

The purpose of the trial is the analysis of safety and efficacy of the chymase inhibitor BAY1142524 at a dose of 25 mg BID in comparison to placebo using a 6 months treatment period in patients with left-ventricular (LV) dysfunction after myocardial infarction (MI). BAY1142524 or placebo will be given on top of evidence-based standard of care for left-ventricular dysfunction after myocardial infarction. Primary objective is the analysis of first signs of efficacy as determined by favourable changes in functional parameters of adverse cardiac remodelling (i.e. endsystolic and enddiastolic volume index, ejection fraction). Secondary objective is the analysis of safety and tolerability as evidenced by the incidence and severity of adverse events. 30 patients have to complete treatment with verum and 30 patients have to complete treatment with placebo.

NCT ID: NCT02976207 Not yet recruiting - OSA Clinical Trials

Long Follow up on Patients With Obstructive Sleep Apnea That Undergo Diagnosis and Surgical Treatment

OSA
Start date: January 2017
Phase: N/A
Study type: Observational [Patient Registry]

Long follow up on patients with obstructive sleep apnea that undergo diagnosis and surgical treatment

NCT ID: NCT02975934 Active, not recruiting - Clinical trials for Metastatic Castration Resistant Prostate Cancer

A Study of Rucaparib Versus Physician's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency

TRITON3
Start date: June 13, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine how participants with metastatic castration-resistant prostate cancer, and evidence of a homologous recombination gene deficiency, respond to treatment with rucaparib versus treatment with physician's choice of abiraterone acetate, enzalutamide, or docetaxel.

NCT ID: NCT02974725 Terminated - Clinical trials for Non-Small Cell Lung Cancer

A Phase Ib Study of LXH254-centric Combinations in NSCLC or Melanoma

Start date: February 24, 2017
Phase: Phase 1
Study type: Interventional

To characterize safety and tolerability and identify a recommended dose and regimen for the LXH254 in combination with LTT462 or trametinib or ribociclib.

NCT ID: NCT02974322 Withdrawn - Crohn Disease Clinical Trials

A Study of Efficacy and Safety of Mongersen (GED-0301) for the Treatment of Adult and Adolescent Subjects With Active Crohn's Disease

Start date: December 1, 2017
Phase: Phase 3
Study type: Interventional

The purpose of study is to test the effect of an experimental medication GED-0301(mongersen) and evaluate its safety in patients (≥ 12 years of age) with active Crohn's disease. The study will test GED-0301 compare to placebo for 12 weeks. The study treatment is blinded which means that patients and the study doctor will not know which treatment has been assigned. Patients in this study will be allowed treatment with stable doses of oral aminosalicylates, oral corticosteroids, immunosupressants and antibiotics for the treatment of Crohn's disease. Adolescent patients will also be allowed treatment with stable doses of exclusive enteral nutrition and growth hormone. All patients who complete the study will have the option to enter a long term active treatment study.

NCT ID: NCT02973555 Not yet recruiting - Infertility Clinical Trials

Platelet-Rich Protein and the Endometrium

Start date: January 2017
Phase: N/A
Study type: Interventional

Platelet-rich plasma (PRP) may promote the endometrial growth and improve pregnancy outcome of patients with thin endometrium undergoing ART treatments.