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NCT ID: NCT03142659 Recruiting - Heart Failure Clinical Trials

Evaluation and Management of Heart Failure Patients

Start date: July 1, 2017
Phase:
Study type: Observational [Patient Registry]

The investigator is trying to improving our knowledge in the treatment of HF patients, for the purpose of improving their quality of life and reducing hospitalizations. For achieving this the investigator would like to build a registry which will include all the HF patients going an evaluation in the Heart Failure unit or clinic in our facility,

NCT ID: NCT03141177 Active, not recruiting - Clinical trials for Renal Cell Carcinoma

A Study of Nivolumab Combined With Cabozantinib Compared to Sunitinib in Previously Untreated Advanced or Metastatic Renal Cell Carcinoma

CheckMate 9ER
Start date: August 22, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether Nivolumab Combined with Cabozantinib is safe and effective compared to Sunitinib in previously untreated advanced or metastatic renal cell carcinoma

NCT ID: NCT03139604 Completed - Clinical trials for Graft-versus-host Disease (GVHD)

GRAVITAS-301: A Study of Itacitinib or Placebo in Combination With Corticosteroids for Treatment of Acute Graft-Versus-Host Disease

Start date: July 19, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate itacitinib or placebo in combination with corticosteroids as first-line treatment of participants with Grade II to IV acute graft-versus-host disease (aGVHD).

NCT ID: NCT03138733 Completed - Clinical trials for Staphylococcus Aureus Bacteremia

Ceftobiprole in the Treatment of Patients With Staphylococcus Aureus Bacteremia

Start date: August 26, 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study was to compare the efficacy and safety of ceftobiprole medocaril versus a comparator in the treatment of patients with complicated Staphylococcus aureus bacteremia (SAB).

NCT ID: NCT03138655 Completed - Ulcerative Colitis Clinical Trials

Vedolizumab IV in Pediatric Participants With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Start date: November 8, 2017
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate vedolizumab pharmacokinetics (PK), safety and tolerability in pediatric participants with moderately to severely active UC or CD.

NCT ID: NCT03138460 Completed - Low Back Pain Clinical Trials

Analysis of Orthopedic Patients Response to New Pain Modulating Substances and Drugs

Start date: January 1, 2015
Phase:
Study type: Observational

Data of patient reported outcomes (PRO) are collected during treatment with various pain alleviation methods (drugs or substances)

NCT ID: NCT03137823 Recruiting - Tonsillitis Clinical Trials

Diagnosis of GABHS Tonsillitis - Comparison Between Culture From Tonsills and Culture From the Bucal Surface

Start date: November 22, 2017
Phase: N/A
Study type: Interventional

Diagnosis of Group A beta hemolytic strep tonsillitis - - cultre of tonsills (gold standard) - culture from bucal surface (test)

NCT ID: NCT03137771 Active, not recruiting - Clinical trials for Stage IV Non-Small Cell Lung Cancer

Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

Start date: April 7, 2017
Phase: Phase 2
Study type: Interventional

This randomized phase II/III trial studies how well giving maintenance chemotherapy with or without local consolidation therapy works in treating patients with stage IV non-small cell lung cancer. Drugs used in maintenance chemotherapy, such as docetaxel, pemetrexed disodium, erlotinib hydrochloride, and gemcitabine work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Local consolidation therapy such as radiation/stereotactic body radiation or surgery may kill cancer cells left after initial treatment. Giving maintenance chemotherapy and local consolidation therapy together may work better than maintenance chemotherapy alone in treating patients with stage IV non-small cell lung cancer.

NCT ID: NCT03137238 Recruiting - Parkinson Disease Clinical Trials

Self-motion Perception in Parkinson's Disease

SMP_PD
Start date: May 1, 2017
Phase:
Study type: Observational

Parkinson's Disease as well as being a disorder of motor function also causes a wide range of non-motor disturbances many of which are involved in the prodromal stage prior to the onset of motor symptoms. Abnormal perception in the visual and in other domains is increasingly being recognized. Control of the movement of our bodies in space involves perception of self-motion which is dependent on the processing and integration of multimodality information from the kinesthetic, proprioceptive, visual (mostly optic flow) and vestibular systems. Dysfunction in this process may contribute to disturbed postural control and thus result in gait abnormalities and falls which are common as Parkinson's disease progresses, is difficult to treat and causes disability and a loss of independence. The integration of information from different modalities ("multisensory integration") is vital for intact perception of the world. Theoretical studies, based on Bayesian statistics, have provided a framework to study multisensory-integration with predictions for an 'optimal' strategy. Many human and animal studies have demonstrated near optimal cue-integration. Yet, while multisensory integration is an active topic of research in normal brain function, with well-established tools, it has not been studied in PD. The investigators hypothesize, based on the apparent over-dependence in PD on visual cues that PD patients will demonstrate defective multisensory integration. This can have profound effects on basic motor functions. Furthermore, based on both visual and vestibular abnormalities (described above) the basic (uni-sensory) performance may also be degraded in PD. In this study the investigators will observe the basic (uni-sensory) and the multisensory integration of visual and vestibular perception of self-motion within the same experiment.

NCT ID: NCT03135704 Not yet recruiting - Low Back Pain Clinical Trials

Comparison of Two Treatments for Low Back Pain: "Re Spine" vs. Physiotherapy

Start date: May 2017
Phase: N/A
Study type: Interventional

The objective of this study is to assess the effectiveness of the "Re Spine" mattress, which was designed as an alternative to physiotherapy in the treatment of low back pain (LBP).