Clinical Trials Logo

Filter by:
NCT ID: NCT03625518 Not yet recruiting - Clinical trials for Fetal Growth Retardation

Mode of Induction in Fetal Growth Restriction and Its Affects on Fetal and Maternal Outcomes

Start date: September 2018
Phase: Early Phase 1
Study type: Interventional

to compare methods of induction of labor in fetal growth restriction and its effect on maternal and neonatal outcome

NCT ID: NCT03625440 Completed - Waterpipe Smoking Clinical Trials

Acute Effects of Waterpipe Smoking on Cognitive Measures and Cardiorespiratory Parameters

Start date: August 2016
Phase: N/A
Study type: Interventional

Title: Acute effects of waterpipe smoking (WPS) on cognitive measures and cardiorespiratory parameters Objectives: To evaluate the acute effect of one cession of water pipe smoking on: 1. executive functions which evaluated by cognitive tests administered included the digit span subtest Wechsler Adult Intelligence Scale (WAIS)-version III hebrew battery, and the Paced Auditory Serial Addition Test (PASAT) 2. Cardiorespiratory parameters included vital signs, spirometry parameters and lung clearance index (LCI) value 3. serum carboxyhemoglobin, nicotine, and cytokines Design: Prospective study evaluating these parameters before and after 30 minutes of water pipe smoking (WPS). Sample size: 55 participants (35 study group, 20 control group) Participant selection: Adults subjects who regularly smoke water pipe. Intervention: Each subject will undergo evaluation including cognitive tests, Cardiorespiratory parameters, carboxy- hemoglobin levels, nicotine levels, serum cytokines levels. All measurements will be evaluated before and after one cession of 30 minutes water pipe smoking

NCT ID: NCT03622580 Completed - Clinical trials for Diabetic Macular Edema

A Study to Evaluate the Efficacy and Safety of Faricimab (RO6867461) in Participants With Diabetic Macular Edema (YOSEMITE)

Start date: September 5, 2018
Phase: Phase 3
Study type: Interventional

This study will evaluate the efficacy, safety, and pharmacokinetics of faricimab administered at 8-week intervals or as specified in the protocol following treatment initiation, compared with aflibercept once every 8 weeks (Q8W), in participants with diabetic macular edema (DME).

NCT ID: NCT03622489 Recruiting - Postoperative Pain Clinical Trials

Comparing Protocols for Analgesia Following Elective Cesarean Section

Start date: March 1, 2017
Phase: Phase 4
Study type: Interventional

Women undergoing elective cesarian section will be assigned to 3 groups for postoperative analgesia: 1. Scheduled doses of IV acetaminophen + PO Ibuprofen 2. Scheduled doses of PO acetaminophen + PO Ibuprofen 3. "On demand" doses of acetaminophen, dipyrone and ibuprofen.

NCT ID: NCT03621644 Active, not recruiting - Pancreatic Cancer Clinical Trials

Stereotactic MRI-guided On-table Adaptive Radiation Therapy (SMART) for Locally Advanced Pancreatic Cancer

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

High-dose magnetic resonance imaging (MRI) guided hypofractionated radiation therapy delivered using daily adaptive dose planning has been shown in a retrospective study to result in improved overall survival, relative to patients receiving lower radiation doses, in patients with locally advanced pancreatic cancer, without increasing the rate of serious gastrointestinal toxicity. The goal of the proposed trial is to investigative in a controlled, prospective manner the robustness of this outcome, and to track quality of life over a 5-year trial period.

NCT ID: NCT03621280 Completed - Cushing Syndrome Clinical Trials

Open-label Treatment in Cushing's Syndrome

OPTICS
Start date: January 7, 2019
Phase: Phase 3
Study type: Interventional

This is a long-term, open-label extension study of levoketoconazole in subjects with endogenous Cushing's Syndrome.

NCT ID: NCT03620747 Completed - Asthma Clinical Trials

Continuation of TRAVERSE- LTS12551 Evaluating Dupilumab Safety in Patients With Asthma (Long-Term Follow-Up)

Start date: August 30, 2018
Phase: Phase 3
Study type: Interventional

Primary Objective: To describe the long-term safety of dupilumab in treatment of participants with moderate to severe asthma who completed the previous asthma clinical trial (TRAVERSE-LTS12551).

NCT ID: NCT03618875 Completed - Pain Clinical Trials

Reduction of Post Intravitreal Injection Bleeding and Pain by Ice

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

Intravitreal injections are an efficient method for delivering intraocular therapeutic agents in numerous ophthalmologic diseases. However, side effects, such as pain and subconjunctival hemorrhage remain a major concern. Prevention or alleviation of those side effects might shorten the healing duration and improve patients' quality of life.

NCT ID: NCT03616912 Terminated - Clinical trials for Systemic Lupus Erythematosus

A Study of Baricitinib (LY3009104) in Participants With Systemic Lupus Erythematosus

SLE-BRAVE I
Start date: August 2, 2018
Phase: Phase 3
Study type: Interventional

The reason for this study is to see how effective and safe the study drug known as baricitinib is in participants with systemic lupus erythematosus (SLE).

NCT ID: NCT03616821 Terminated - Ulcerative Colitis Clinical Trials

Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis

Expedition
Start date: August 7, 2018
Phase: Phase 2
Study type: Interventional

The present study (D5272C00001/Legacy #3151-201-008) aims to evaluate the efficacy and safety of brazikumab in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy