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NCT ID: NCT02762656 Not yet recruiting - Spinal Diseases Clinical Trials

The Effect of Perioperative Lidocaine Intravenous Infusion on Postoperative Recovery After Spine Surgery.

Start date: June 2016
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of perioperative Lidocaine intravenous infusion in reducing postoperative pain for spine surgery patients.

NCT ID: NCT02749773 Not yet recruiting - Infertility Clinical Trials

Is There a Difference in Oocyte Quality? A Comparison of Two Aspiration Needle Gauges

Start date: May 2016
Phase: N/A
Study type: Interventional

The aim of this study is to determine whether different needle gauges influences the quality of the aspirated oocytes during in-vivo fertilization (IVF).

NCT ID: NCT02747563 Not yet recruiting - Prostate Cancer Clinical Trials

Evaluation of PSA Blood Levels Prior to and After Digital Rectal Examination

Start date: May 2016
Phase: Phase 1
Study type: Interventional

Patients with know prostate cancer (PCa) under active surveillance and aged matched controls without evidence of PCa will have a PSA blood test prior to and following standardized digital rectal examination

NCT ID: NCT02738242 Not yet recruiting - Muscle Weakness Clinical Trials

Evaluation of Usability and Human Factors in the Novus System

Start date: May 2016
Phase: N/A
Study type: Interventional

The Novus system intended to provide ankle dorsiflexion and knee flexion or extension in individuals with foot drop and thigh muscle weakness, following an upper motor neuron injury or disease. The primary objective of the study is to evaluate the usability of the Novus system among these patients and to gain subjects' feedback regarding the device when used on a daily basis.The secondary objective is to obtain information about the performance of the system as a gait assistive device and to evaluate the subject's Quality of Life while using the system.

NCT ID: NCT02731781 Not yet recruiting - Clinical trials for TO FIND THE CORRELATION BETWEEN TINS SCORE OUTCOME

Trauma Infant Neurological Score (TINS) as a Prognostic Factor and Guideline for CT Scan in Infants 24 Months Old or Less

Start date: April 2016
Phase: N/A
Study type: Observational [Patient Registry]

Traumatic brain injury (TBI) is the major cause of disability and death among the younger population. In the Pediatric population Head trauma may be responsible for primary and secondary brain damage. Primary brain injury results from a direct mechanical damage at the time of injury, whereas secondary injury is caused by further cellular damage that develops hours or days post injury. Intracranial Injury in Infants (III) may be hard to diagnose in the abcence of neurological deficit or early deterioration. On the other hand, symptoms such as vomiting and restlessness may be present even in the case of minor head injury, and unnesessary scaning (CT) may be performed in many centers just because clinical judgment is problematic in this particular age. Some intracranial injuries may be imminent, such as evolving Epidural hematoma (EDH) in infants, and early diagnosis may be lifesaving and leading to excellent outcome. In adults, GCS has been accepted as the most usuful tool for emergency evaluation of head injured patients. In children, several scores were introduced, including the Children's Coma Score (CCS), however they have been found problematic to use in the very young population, since accurate evaluation of communication in CCS is hard, and there is insufficient relevant parameters uncorporated into the score that may have significant importance in this particular age group. In TINS (Trauma Infant Neurological Score) we characterized the clinical parameters and the mechanism of trauma in a simplified method. As previously published, this score has been used by us and by other groups, in retrospective studies. Still, in the lack of prospective studies using TINS, there are no optimal guidelines to perform computed tomography (CT) in this unique population, and TINS has not prospectively been challenged as a predictor tool for outcome. In this prospective study we will approach these issues.

NCT ID: NCT02727595 Not yet recruiting - Hallux Valgus Clinical Trials

Evaluation of CyclaPlex Implant for Correction of First Inter Metatarsal Angle in Subjects Suffering From Hallux Valgus Deformity

Start date: April 2016
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate safety, tolerability and performance of the CyclaPlex implant, a button and suture type implant device and instruments for the correction of the first inter metatarsal angle in subjects suffering from Hallux Valgus deformity.

NCT ID: NCT02719041 Not yet recruiting - Ovarian Cancer Clinical Trials

Predictive Biomarkers for IGF1R Targeted Therapy in Ovarian Cancer: a Retrospective Study

Start date: April 2016
Phase: N/A
Study type: Observational

The main goal of this study is to employ a novel proteomic approach to identify predictive tumor biomarkers that will increase the efficacy of insulin-like growth factor (IGF1R) targeted therapy in epithelial ovarian cancer. It is expected that these predictive biomarkers will be applied to increase the response rate in selected groups of patients.

NCT ID: NCT02718209 Not yet recruiting - Clinical trials for Gynecological Malignancies

The Development of an In-vitro System to Identify Gynecologic Cancer Cells During Surgical Procedures

Start date: April 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the efficacy of mid-infrared spectroscopy together with Attenuated Total Reflection (ATR), for the detection of gynecological malignancies in real time during surgery.

NCT ID: NCT02711865 Not yet recruiting - Ovarian Cancer Clinical Trials

Predictive Biomarkers for IGF1R Targeted Therapy in Ovarian Cancer

Start date: May 2016
Phase: N/A
Study type: Observational

The main goal of this study is to employ a novel proteomic approach to identify predictive tumor biomarkers that will increase the efficacy of insulin-like growth factor (IGF1R) targeted therapy in epithelial ovarian cancer. It is expected that these predictive biomarkers will be applied to increase the response rate in selected groups of patients.

NCT ID: NCT02711436 Not yet recruiting - Orbital Cellulitis Clinical Trials

Fast Magnetic Resonance Imaging as Compared to Computed Tomography Scan in Pediatric Orbital Cellulitis Imaging

Start date: April 2016
Phase: N/A
Study type: Interventional

The aim of the study is to compare orbital and central nervous system (CNS) imaging with Computed Tomography (CT) scan to that of Fast Magnetic Resonance Imaging (Fast MRI) in children with mild, moderate or severe orbital cellulitis with medical indications for imaging.