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NCT ID: NCT02001428 Completed - Clinical trials for Plasmodium Falciparum Malaria

Malaria in Early Life Study

Start date: July 21, 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effectiveness of different malaria control strategies in the first year of life. The effectiveness of delivering an intermittent screening and treatment programme with dihydroartemisinin-piperaquine (DHP), linked to local immunization programmes, will be compared to the current practice of passive case detection of malaria. This study has two objectives: 1. To assess the effectiveness of intermittent screening and treatment with dihydroartemisinin-piperaquine (DHP) administered at 2, 3, 4 and 9 months of age compared with the current practice of passive detection and treatment for malaria in an area with high drug resistance levels to both P. falciparum and P. vivax. 2. To evaluate the safety, efficacy and population pharmacokinetics of DHP in children under 1 year of age.

NCT ID: NCT01999686 Completed - Insulin Resistance Clinical Trials

PCOS Treatment Using DLBS3233, Metformin, and Combination of Both

POSITIF
Start date: October 2014
Phase: Phase 3
Study type: Interventional

This is a 3-arm, randomized, double-blind, double-dummy, and controlled clinical study over 6 months of treatment to evaluate the metabolic and clinical efficacy as well as the safety of DLBS3233 alone, metformin and combination of both, in improving metabolic and reproductive parameters.

NCT ID: NCT01998919 Completed - Clinical trials for Non-Small Cell Lung Cancer

A Study of Tarceva (Erlotinib) in Combination With Platinum Based Chemotherapy in Patients With Non-Small Cell Lung Cancer.

Start date: August 2006
Phase: Phase 2
Study type: Interventional

This study will evaluate the efficacy and safety of sequential administration of Tarceva and gemcitabine/platinum chemotherapy in patients with stage IIIb/IV non-small cell lung cancer. Patients will be randomized to receive Tarceva (150 mg po) or placebo on days 15-28 of a 4 week cycle of intravenous platinum-based chemotherapy, for a total of 6 cycles. The anticipated time on study treatment is until disease progression or unacceptable toxicity.

NCT ID: NCT01987921 Completed - Acute Kidney Injury Clinical Trials

Observational Study of Pediatric Acute Kidney Injury, Risk Factors and Outcomes

AWARE
Start date: January 2014
Phase: N/A
Study type: Observational [Patient Registry]

Pediatric acute kidney injury (AKI) is associated with increased morbidity and mortality in critically ill patients. Currently, understanding of the epidemiology and diagnosis of AKI in children is limited by single center retrospective data and inconsistent diagnostic and stratification criteria. The hypotheses of the AWARE study is that 1) renal angina, a composite of early injury signs and risk of disease, will predict severe subsequent AKI in critically ill children and 2) the incorporation of urinary biomarkers into the renal angina scoring system will improve the prediction of the severe injury. The AWARE study is conducted to describe AKI epidemiology in a heterogeneous multinational cohort of critically ill children, characterize AKI risk factors and associated morbidity, and validate the KDIGO AKI criteria as a predictor of pediatric AKI outcomes. The multi-center, multi-national registry will create the largest ever repository of information available on AKI in children.

NCT ID: NCT01986335 Completed - Healthy Clinical Trials

Protectivity and Safety of DTP/HB/Hib (Bio Farma) Vaccines in Infants, Batch Consistency, Multi Center Trial

Start date: August 2012
Phase: Phase 3
Study type: Interventional

The objectives of this study were to analyze the immunogenicity and reactogenicity of DTP/HB/Hib (Bio Farma) combination vaccine.

NCT ID: NCT01986322 Completed - Healthy Clinical Trials

Immunogenicity and Safety of DTP/HB/Hib (Bio Farma)Compared to DTP/HB Given Simultaneously With Hib(Registered)Vaccine

Start date: July 2011
Phase: Phase 2
Study type: Interventional

The main objective of this study was to evaluate the protectivity and safety of DTP/HB/Hib (Bio Farma) vaccine compared to DTP/HB and Hib vaccine given simultaneously.

NCT ID: NCT01977196 Completed - Healthy Clinical Trials

The Safety and Immunogenicity of DTP/Hepatitis B 10ug Hib Vaccine (Bio Farma)

Start date: April 2011
Phase: Phase 1
Study type: Interventional

The objective of this study was to know the safety of DTP/Hepatitis B and Hib/PRP-T vaccine and immediate reactions within the first 30 minutes after injection.

NCT ID: NCT01977170 Completed - Healthy Clinical Trials

Safety of Hib Vaccine (Bio Farma)

Start date: November 2010
Phase: Phase 1
Study type: Interventional

The objective of this study was to know the safety of Hib/PRP-T vaccine and immediate reactions within the first 30 minutes after injection.

NCT ID: NCT01976338 Completed - Clinical trials for Branch Retinal Vein Occlusion

Ranibizumab Intravitreal Injections Versus Sham Control in Patients With Branch Retinal Vein Occlusion (BRVO)

Blossom
Start date: November 2013
Phase: Phase 3
Study type: Interventional

To provide efficacy and safety data on intravitreal injections of ranibizumab 0.5 mg in patients with visual impairment due to macular edema secondary to BRVO

NCT ID: NCT01976312 Completed - Clinical trials for Central Retinal Vein Occlusion

Ranibizumab Intravitreal Injections Versus Sham Control in Patients With Central Retinal Vein Occlusion (CRVO)

Camellia
Start date: November 2013
Phase: Phase 3
Study type: Interventional

To provide efficacy and safety data on intravitreal injections of ranibizumab 0.5 mg in patients with visual impairment due to macular edema secondary to CRVO