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NCT ID: NCT00198497 Completed - Clinical trials for Diabetic Retinopathy

Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage

Start date: June 1999
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if intravitreal injection of Vitrase (ovine hyaluronidase) clears vitreous hemorrhage

NCT ID: NCT00195715 Completed - Crohn's Disease Clinical Trials

Long-term Safety and Tolerability Study of Adalimumab in Subjects With Crohn's Disease

Start date: September 2004
Phase: Phase 3
Study type: Interventional

To evaluate the long-term maintenance of response, safety and tolerability of repeated administration of adalimumab in subjects with Crohn's disease who participated in and successfully completed Protocol M02-404 or Protocol M04-691.

NCT ID: NCT00195546 Completed - Menopause Clinical Trials

Study Evaluating DVS-233 SR for Treatment of Vasomotor Symptoms Associated With Menopause

Start date: April 2005
Phase: Phase 3
Study type: Interventional

Primary: To assess the efficacy and safety of DVS-233 SR compared with placebo for treatment of vasomotor symptoms (VMS) associated with menopause and to compare the bleeding incidence of DVS-233 SR and tibolone. Secondary: To assess the effects of DVS-233 SR and tibolone on changes from baseline in weight, breast pain, and health outcomes indicators.

NCT ID: NCT00195507 Completed - Psoriasis Clinical Trials

Study Evaluating Etanercept in the Treatment of Subjects With Psoriasis

Start date: December 2004
Phase: Phase 4
Study type: Interventional

This study will provide a direct comparison of 'continuous therapy' and 'intermittent therapy' with withdrawal and retreatment upon return of psoriasis.

NCT ID: NCT00191282 Completed - Clinical trials for Diabetes Mellitus, Type 2

Hyperglycemia and Cardiovascular Outcomes With Type 2 Diabetes

IONM
Start date: October 2002
Phase: Phase 4
Study type: Interventional

The primary objective was to demonstrate a difference between two insulin strategies, one targeting postprandial (PP) hyperglycemia and the other targeting fasting and interprandial hyperglycemia, on time until the first combined adjudicated cardiovascular (CV) event (primary outcome defined as CV death, nonfatal myocardial infarction [MI], nonfatal stroke, coronary revascularization, or hospitalized acute coronary syndrome).

NCT ID: NCT00191126 Completed - Clinical trials for Non-Small Cell Lung Cancer

Randomized Phase III Trial of Surgery Alone or Surgery Plus Preoperative Gemcitabine-Cisplatin in Early Stages NSCLC

Start date: September 2000
Phase: Phase 3
Study type: Interventional

Preoperative chemotherapy is considered to play a role in early stage non small cell lung cancer (NSCLC) .The use of preoperative Cisplatin/Gemcitabine chemotherapy has proven feasible and without excessive morbidity or mortality in the Phase II setting. The aim of the present Phase III study is to determine whether 3 cycles of preoperative chemotherapy with Cisplatin/Gemcitabine improves progression free survival of NSCLC patients versus surgery alone. Postoperative chemotherapy will not be utilized in this Phase III trial.

NCT ID: NCT00190892 Completed - Bipolar Disorder Clinical Trials

Olanzapine Plus Carbamazepine in the Treatment of Bipolar I Mania

Start date: September 2004
Phase: Phase 4
Study type: Interventional

This trial will assess any efficacious benefit and any safety issues associated with the concomitant use of olanzapine and carbamazepine for the treatment of patients with bipolar I disorder, manic or mixed episodes

NCT ID: NCT00190671 Completed - Breast Cancer Clinical Trials

A Study of Pemetrexed and Cyclophosphamide Given Every 21 Days in Advanced Breast Cancer Patients

Start date: June 2005
Phase: Phase 1/Phase 2
Study type: Interventional

This is the phase 2 portion of a phase 1/2 trial, testing the use of pemetrexed and cyclophosphamide in combination for the treatment of advanced breast cancer. A single arm Phase 1 dose finding (establish maximum tolerated dose) study precedes the randomized phase 2 portion.

NCT ID: NCT00189839 Completed - Clinical trials for Kidney Transplantation

A Study to Evaluate the Safety and Efficacy of FK506E (MR4) in Patients Undergoing Primary Kidney Transplantation

Start date: August 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate and to compare the efficacy and safety of a triple modified release tacrolimus FK506E (MR4) / MMF / steroid regimen with a triple standard tacrolimus FK506 / MMF / steroid regimen in patients undergoing kidney transplantation. It shall be demonstrated that FK506E (MR4) is non-inferior to FK506 with regards to the primary endpoint.

NCT ID: NCT00189787 Completed - Bronchial Asthma Clinical Trials

Dose Response of Inhaled Tacrolimus in Patients With Moderate Persistent Asthma

Start date: n/a
Phase: Phase 2
Study type: Interventional

This study will evaluate the efficacy and safety of tacrolimus in patients with asthma.