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NCT ID: NCT00908232 Completed - Multiple Myeloma Clinical Trials

Treatment With Velcade (Bortezomib) Plus Dexamethasone (VD) or VD Plus Cyclophosphamide or VD Plus Lenalidomide in Patients With Multiple Myeloma Stabilized After 4 Cycles of VD

SEQUENTIAL
Start date: May 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to test the effectiveness and safety of adding cyclophosphamide or lenalidomide to the VD combination in the treatment of patients with multiple myeloma that have achieved a stable response after 4 initial cycles of treatment with VD. Multiple myeloma is the second most common cancer of the blood. Bortezomib disrupts the life cycle of the cell, affecting numerous biologic pathways, including those related to growth and survival of cancer cells.

NCT ID: NCT00907296 Completed - Fracture Healing Clinical Trials

Study of Romosozumab (AMG 785) in Tibial Diaphyseal Fractures Status Post Intramedullary Nailing

STARTT
Start date: September 2, 2009
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to investigate the effect of romosozumab compared with placebo on time to radiographic healing of fresh tibial diaphyseal fractures (fractures in the midsection of the shinbone).

NCT ID: NCT00905684 Completed - Contraception Clinical Trials

Effects of Counseling on the Continuation Rates and Compliance for Newly Prescribed Oral Contraceptives (Yasmin® or Any Other Oral Contraceptives (OC)

Start date: June 2009
Phase: N/A
Study type: Observational

This study is a prospective, company-sponsored, non-interventional cohort study of up to 5000 patients in European countries and countries in Middle East who are newly prescribed any available OC. Patients will be followed up approximately 6 months after initial visit. Selection of Study Population: Women can be enrolled after decision for treatment with Yasmin or any other OC has been made. Physicians should consult the full prescribing information for the respective OC before enrolling patients and familiarize themselves with the safety information in the product package label.

NCT ID: NCT00903682 Completed - HIV Clinical Trials

A Clinical Trial Comparing the Tolerability of Etravirine to Efavirenz in Combination With 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Treatment-naive HIV-1 Infected Patients

SENSE
Start date: June 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare the neuropsychiatric adverse event profiles of etravirine 400mg once daily versus efavirenz 600mg once daily, in combination with 2 N(t)RTIs, in approximately 150 treatment-naÃ-ve HIV-1 infected patients. Safety, tolerability and efficacy of both treatment arms will be assessed throughout the study.

NCT ID: NCT00903383 Completed - Clinical trials for Rheumatoid Arthritis

Study of LX3305 in Subjects With Active Rheumatoid Arthritis on Stable Methotrexate

Start date: July 2009
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate the safety, tolerability, and effectiveness of LX3305 versus a placebo control in subjects with active rheumatoid arthritis on stable methotrexate therapy.

NCT ID: NCT00902928 Completed - Clinical trials for Venous Thromboembolism

A Study Evaluating Efficacy and Safety of YM150 Compared to Enoxaparin in Subjects Undergoing Hip Replacement Surgery

ONYX-3
Start date: April 2009
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of various doses of YM150 (the experimental drug) compared to enoxaparin in the prevention of venous thromboembolism in patients that are undergoing elective hip replacement surgery.

NCT ID: NCT00902837 Completed - Clinical trials for Chronic Osteoarthritis

OXN PR Compared to OxyPR to Demonstrate Non-inferiority in Pain & Locomotor Function & Improvement in Symptoms of Constipation in OA Subjects

Start date: May 2009
Phase: Phase 3
Study type: Interventional

The primary objectives are - to demonstrate that the treatment with OXN PR tablets is non-inferior to the treatment with OxyPR with regards to analgesic efficacy and locomotor function. - to demonstrate that subjects with moderate to severe OA pain taking oxycodone/naloxone prolonged release tablets have improvement in symptoms of constipation compared to subjects taking oxycodone prolonged release tablets alone

NCT ID: NCT00902369 Completed - Clinical trials for Rheumatoid Arthritis

A Study of AK106-001616 in Patients With Rheumatoid Arthritis (RA)

Start date: May 2009
Phase: Phase 2
Study type: Interventional

This will be a Phase II, multi-centre study consisting of 2 parts. Part 1: Clinical Pharmacology Study (drug-drug interaction between AK106-001616 and methotrexate) Part 2: Proof of Concept Study

NCT ID: NCT00900861 Completed - Clinical trials for Asthma Control Level

Asthma Control and Clinical Practice in Hungary 2009

Start date: April 2009
Phase: N/A
Study type: Observational

A prospective study led amongst pulmonologists. Patients asthma control level will be evaluated based on GINA guideline criteria. HRQoL measured by Visual analogue scale. Clinical practice: non controlled patients therapy assessed.

NCT ID: NCT00900731 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

A Study to Compare the Lung Effect of Indacaterol and Tiotropium in Chronic Obstructive Pulmonary Disease (COPD)

INTENSITY
Start date: June 2009
Phase: Phase 3
Study type: Interventional

This study compared the lung effects of indacaterol to those of tiotropium in patients with moderate to severe chronic obstructive pulmonary disease (COPD) over a 12 week period.