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NCT ID: NCT01225822 Completed - Clinical trials for Venous Thromboembolism

BIBR 1048 Dose Range Finding Study in Prevention of Venous Thromboembolism in Patients With Primary Elective Total Hip or Knee Replacement Surgery

Start date: November 2002
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to establish the dose-response relationship with regard to efficacy and safety of BIBR 1048 (50 mg bis in die(b.i.d), 150 mg b.i.d, 225 mg b.i.d. and 300 mg quaque die(q.d) ) in preventing venous thromboembolism(VTE) in patients undergoing primary elective total hip and knee replacement.

NCT ID: NCT01225666 Completed - Clinical trials for Adult Growth Hormone Deficiency

MOD-4023 (Long-Lasting Human Growth Hormone (hGH)) Study in Growth Hormone Deficient Adults (GHDA)

Start date: August 2010
Phase: Phase 2
Study type: Interventional

This study aims to assess the safety, tolerability and Pharmacokinetics/ Pharmacodynamics (PK/PD) profile of three doses of MOD-4023 on a weekly regime and one dose on an every-other-week regime administered for a period of 4 weeks in Growth Hormone Deficient Adult (GHDA) patients who previously were on a stable r-hGH treatment. An additional extension period of 16 weeks once-weekly administration of MOD-4023 aims to confirm the dose selection for future trials.

NCT ID: NCT01225562 Completed - Stroke Clinical Trials

Prevention of Cardiovascular Events (eg, Death From Heart or Vascular Disease, Heart Attack, or Stroke) in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin

PEGASUS
Start date: October 2010
Phase: Phase 3
Study type: Interventional

This study is being carried out to see if a new drug called ticagrelor given twice daily in addition to the ASA therapy decreases the frequency of cardiovascular events (e.g., death from heart disease, heart attack, or stroke).

NCT ID: NCT01225393 Completed - Clinical trials for Rheumatoid Arthritis

A Study to Evaluate the Efficacy and Safety of MLTA3698A in Combination With a Disease-Modifying Anti-Rheumatic Drug (DMARD) Compared With Adalimumab in Combination With a DMARD in Patients With Active Rheumatoid Arthritis

Start date: November 2010
Phase: Phase 2
Study type: Interventional

This is a Phase II, randomized, double-blind, placebo-controlled, parallel-group, multicenter study enrolling patients with active rheumatoid arthritis (RA).

NCT ID: NCT01225315 Completed - Asthma Clinical Trials

Clinical Study to Explore the Efficacy of ACT-129968 in Patients With Partly Controlled Asthma

CONTROL
Start date: November 1, 2010
Phase: Phase 2
Study type: Interventional

This study will assess the efficacy and safety of ACT-129968 in subjects with partly controlled asthma on reliever therapy only.

NCT ID: NCT01224834 Completed - Clinical trials for Rhinitis, Allergic, Seasonal

Safety and Tolerability Study of Ragweed SLIT Tablets

Start date: January 2009
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the safety and tolerability of several doses of ragweed pollen allergen extract administered as sublingual tablets in subjects with allergic rhinitis to ragweed.

NCT ID: NCT01224366 Completed - Clinical trials for Type 2 Diabetes Mellitus

Efficacy and Safety of Vildagliptin as add-on Therapy to Insulin in Patients With Type 2 Diabetes Mellitus

Start date: September 2010
Phase: Phase 3
Study type: Interventional

To assess the efficacy and safety of vildagliptin add-on therapy to reduce HbA1c in patients with T2DM inadequately controlled by insulin, with or without concurrent metformin therapy.

NCT ID: NCT01223911 Completed - Clinical trials for Rheumatoid Arthritis

A Multiple Dose Trial of NNC 0151-0000-0000 in Subjects With Rheumatoid Arthritis

Start date: January 2011
Phase: Phase 2
Study type: Interventional

This trial is conducted in Europe. The aim of this clinical trial is to investigate the safety, tolerability and pharmacokinetics (at which rate the drug is eliminated from the body) of NNC 151-0000-0000 in subjects with rheumatoid arthritis (RA).

NCT ID: NCT01223352 Completed - Clinical trials for Pulmonary Arterial Hypertension

Effects of Two Dosing Regimens of Bosentan in Children With Pulmonary Arterial Hypertension

FUTURE 3
Start date: March 8, 2011
Phase: Phase 3
Study type: Interventional

The primary objective of AC-052-373 was to assess the pharmacokinetic (PK) profile of two dosing regimens of the pediatric formulation of bosentan in children with pulmonary arterial hypertension (PAH) <12 years of age.

NCT ID: NCT01223222 Completed - Atopic Dermatitis Clinical Trials

A Study to Evaluate Safety, Tolerability and Efficacy of Lytixarâ„¢ (LTX-109) on Uncomplicated, Gram-positive, Skin Infection

Start date: September 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability of Lytixarâ„¢ applied topically to uncomplicated skin infections. Three dose levels of Lytixarâ„¢ (1%, 2% and 5%) versus placebo will be tested.