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NCT ID: NCT01004224 Completed - Clinical trials for Advanced Solid Tumors With FGFR1 Amplication

A Dose Escalation Study in Adult Patients With Advanced Solid Malignancies

Start date: December 11, 2009
Phase: Phase 1
Study type: Interventional

The study will determine the maximum tolerated dose and thus the recommended phase II dose and schedule of the compound and characterize the safety.

NCT ID: NCT01004029 Completed - Preterm Birth Clinical Trials

Confirmatory Study of 17P vs Vehicle for Prevention of Preterm Birth in Women w/ Previous Spontaneous Preterm Delivery

PROLONG
Start date: October 2009
Phase: Phase 3
Study type: Interventional

As part of the continuing effort to study the benefit and risks of 17P and preterm delivery, this study is designed as a multi-center, randomized, double-blind, vehicle-controlled clinical trial of 17P for the prevention of preterm birth prior to 35 weeks, 0 days of gestation in women with a singleton pregnancy, aged 18 years or older, with a previous singleton spontaneous preterm delivery. The study also includes a population pharmacokinetic (PK) substudy to assess the hydroxyprogesterone caproate (HPC) exposure-response relationship and the effect of body mass index (BMI) on the PK of 17P.

NCT ID: NCT01003990 Completed - HIV Clinical Trials

Roll-Over Protocol To Provide Atv And/Or Truvada For Extended Access

Start date: October 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to provide atazanavir or tenofovir-emtricitabine to HIV-infected subjects who have completed atazanavir or tenofovir-emtricitabine therapy on a previous BMS sponsored clinical trial

NCT ID: NCT01003015 Completed - Clinical trials for Carcinoma, Hepatocellular

Safety Study of BAY73-4506 in Patients With Hepatocellular Carcinoma

Start date: September 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether BAY73-4506 treatment is safe and can shrink or delay the growth of tumors in patients with unresectable liver cancer.

NCT ID: NCT01001858 Completed - Clinical trials for Obstructive Sleep Apnea

Domiciliary Diagnosis and Follow up in Obstructive Apnoea Syndrome

Start date: June 2003
Phase: N/A
Study type: Interventional

The aim of the investigators study was to evaluate the effectiveness of a home programme (diagnosis and follow-up) in patients with Obstructive Sleep Apnea (OSA) syndrome treated with CPAP and to analyze the cost of this approach.

NCT ID: NCT01001494 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Efficacy and Safety of Aclidinium Bromide at Two Dose Levels Versus Placebo Administered in Chronic Obstructive Pulmonary Disease (COPD) Patients

Start date: October 2009
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to assess the long term bronchodilator efficacy, safety and tolerability of inhaled aclidinium bromide at two dose levels compared to placebo in COPD patients and the benefits of the product in disease-related health status, COPD symptoms and COPD exacerbations.

NCT ID: NCT01001338 Completed - Gout Clinical Trials

Allopurinol Combination Study

RDEA594-203
Start date: October 2009
Phase: Phase 2
Study type: Interventional

To compare the proportion of subjects whose serum urate (sUA) levels are < 6.0 mg/dL following 4 weeks of continuous treatment of RDEA594 in combination with allopurinol to allopurinol alone in subjects with documented inadequate hypouricemic response with standard doses of allopurinol.

NCT ID: NCT01000727 Completed - Clinical trials for Acute Coronary Syndrome

The Stabilization Of pLaques usIng Darapladib-Thrombolysis In Myocardial Infarction 52 Trial

SOLID-TIMI 52
Start date: December 2009
Phase: Phase 3
Study type: Interventional

This study will test whether darapladib can safely lower the chances of having a cardiovascular event (such as a heart attack or urgent coronary revascularization (e.g. medical procedures performed to restore the normal blood flow in patients with atherosclerosis)) when treatment is started within 30 days after an acute coronary syndrome (also called ACS).

NCT ID: NCT01000480 Completed - Clinical trials for Non Small Cell Lung Cancer

A Study of Pemetrexed and Cisplatin, in Non Small Cell Lung Cancer

Start date: October 2009
Phase: Phase 2
Study type: Interventional

This trial investigates pemetrexed and cisplatin followed by pemetrexed and cisplatin in combination with radiotherapy in participants with locally advanced, non-small cell lung cancer (NSCLC). The purpose of the study is to assess the antitumor activity as measured by progression free survival 1 year after start of treatment with study drug.

NCT ID: NCT00999115 Completed - Crohn Disease Clinical Trials

Allogenic Stem Cells Derived From Lipoaspirates for the Treatment of Recto-vaginal Fistulas Associated to Crohn`s Disease (ALOREVA)

ALOREVA
Start date: September 2009
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine safety and efficacy of allogenic eASCs (expanded adult stem cells) for the treatment of recto-vaginal fistula in patients with Crohn´s disease.