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NCT ID: NCT02245477 Recruiting - Clinical trials for Foetal Growth Restriction

Maternal Serum Vascular Endothelial Growth Factor in Pregnant Women With Foetal Growth Restriction

VEGF in FGR
Start date: September 2014
Phase:
Study type: Observational

In this study we explore To explore the role of maternal serum vascular endothelial growth factor (VEGF) in pregnancies complicated by foetal growth restriction.

NCT ID: NCT02244567 Recruiting - Clinical trials for Polycystic Ovarian Syndrome

Effect of Metformin Therapy on Serum Under-carboxylated Osteocalcin Levels in Hyperandrogenic Lean Polycystic Ovarian Syndrome Women

U-C OC IN PCOS
Start date: September 2014
Phase: Phase 1
Study type: Interventional

High ucOC may favor insulin release in lean hyperandrogenic women to compensate for impaired insulin sensitivity. Meformin is an insulin sensitizing agent will be given for these women trying to interfere with the pathophysiology of PCOS in these women as followed up by serum UC-OC levels.

NCT ID: NCT02226211 Recruiting - Clinical trials for Failed or Difficult Intubation (Anaesthesia Complications)

Ambu Aura-i Laryngeal Mask Versus Air-Q Intubating Laryngeal Airway for Tracheal Intubation in Adults

Start date: June 2014
Phase: Phase 3
Study type: Interventional

Supraglottic airway devices (SGA) become a routine part of the daily anesthesia practice. they can be used as primary airway devices or as conduits for endoracheal intubation and they become an integral part in the recent guidelines for managing difficult airway. Air-Q ILA has been used successfully as 1ry airway and also as a conduits for endotracheal intubation. The Ambu® Aura-i TM laryngeal mask is a new disposable SGA claimed to have special advantage over the competitors but not will studied as a conduit for endoracheal intubation. This study is designed to compare the performance of Ambu®Aura-i™ laryngeal mask with the air-Q ILA as conduits for fiberoptic-guided tracheal intubation in adult population.

NCT ID: NCT02221570 Recruiting - Liver Cirrhosis Clinical Trials

Baclofen in the Treatment of Muscle Cramps in Patients With Cirrhosis

Start date: June 2014
Phase: N/A
Study type: Interventional

Patients with cirrhosis often experience muscle cramps with varying severity. The mechanism of their occurrence is not yet understood. Muscle cramps in patients with cirrhosis are associated with significantly diminished quality of life. The aim of the study is to assess the efficacy of baclofen in the treatment of muscle cramps in patients with liver cirrhosis.

NCT ID: NCT02215525 Recruiting - Hepatitis C Clinical Trials

Treatment of Chronic HCV Infected Egyptian Patients With Electromagnetic Waves and Herbal Therapy

Start date: April 2014
Phase: Phase 3
Study type: Interventional

A Randomized, Open-Label, Study to evaluate and compare the efficacy and safety, of extracorporeal irradiation of circulating blood by UVA with antioxidant as a supplement (Selenium containing food supplement herbal tablets) in the treatment of non-cirrhotic subjects with chronic hepatitis C.

NCT ID: NCT02190006 Recruiting - Clinical trials for Polycystic Ovarian Syndrome

Comparison Between the Role of Follicular Output Rate and Preovulatory Count in the Prediction of Pregnancy in Women With Polycystic Ovarian Syndrome Undergoing Intra Cytoplasmic Sperm Injection (ICSI)

Start date: July 2014
Phase: N/A
Study type: Observational

Our study is observational, we are observing data from routine measurements during IVF/ICSI. Our study does not assess IVF/ICSI as an intervention, we are evaluating the role of FSI and preovulatory count which are calculated by observing routine measurements during the IVF/ICSI procedure. 300 women with polycystic ovarian syndrome (PCOS) who are decided to be treated with ICSI. will be subjected to full history taking and clinical examination. On the second day of menstruation serum FSH, LH, Prolactin and Oestradiol will be assessed and the antral follicular count (AFC) will be assessed using a vaginal ultrasound scan. AFC will be defined as the number of follicles measuring 3-10mm. All patients will have standard pituitary down-regulation followed by follicle stimulating hormone (FSH) stimulation until the day of Human chorionic gonadotrophin (HCG) administration. On the day of HCG administration, ovarian ultrasound scan will be performed using a transvaginal probe and the Preovulatory follicle count (PC) will be assessed, (PFC) is defined as number of follicles measuring≥16mm. Follicular output rate (FORT) will be calculated as: (FSI =PFC*10000/AFC*Total dose of FSH). FORT correlation to pregnancy will be compared to that of the preovulatory count number

NCT ID: NCT02186782 Recruiting - Infertility Clinical Trials

Concomitant CC and E2 Versus CC Alone in Ovulation Induction

Start date: June 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effect of concomitant administration of estradiol during use of clomiphene citrate (CC) for induction of ovulation in infertile women.

NCT ID: NCT02168881 Recruiting - Labour Induction Clinical Trials

Oral Misoprostol Versus Vaginal Dinoprostone For Induction Of Labour: A Randomized Controlled Clinical Trial

Start date: May 2014
Phase: N/A
Study type: Interventional

This study is to compare between oral misoprostol in solution and vaginal dinoprostone in induction of labour in primiparous women with singleton pregnancy as regards efficiency and safety to both mother and fetus.

NCT ID: NCT02164773 Recruiting - Agitation Clinical Trials

Addition of Magnesium Sulfate to Caudal to Prevent Postoperative Emergence Agitation.

Start date: October 2013
Phase: Phase 4
Study type: Interventional

Emergence agitation after sevoflurane anesthesia is still a problem needed to be solved.The aim of the study is to delineate the effect of caudal magnesium sulfate in children undergoing lower abdominal surgery to prevent postoperative emergence agitation.

NCT ID: NCT02161003 Recruiting - Fecal Incontinence Clinical Trials

Stem Cells Therapy for Fecal Incontinence in Children After Posterior Sagittal Ano-rectoplasty

Start date: October 2013
Phase: Phase 1/Phase 2
Study type: Interventional

The problem of the incontinence imposes considerable strain on the child and their parents. These patients suffer from a long-life handicap and they need support and follow-up. The cost associated with these diseases has clearly been illustrated to be a major component in the healthcare spending picture, may be adding hundreds of thousands of dollars to healthcare cost, as well as loss of productivity in the work force. Fecal incontinence treatment has been a difficult challenge for surgeons for several generations until now the current traditional surgical result is unsatisfactory. Mesenchymal Stem Cells injection may represent a new attractive treatment option for anal sphincter lesions. Moreover, experimental injury of muscle of anal sphincter in rats has been successfully treated with stem cells injections. In this study, the investigators will shed more light on the ability of Mesenchymal Stem Cells to induce myogenesis and regenerate anal Sphincter of patients with fecal incontinence. It will be very useful to many Egyptian patients.