Clinical Trials Logo

Filter by:
NCT ID: NCT03608514 Recruiting - Clinical trials for Resolution of Septic Shock With Terlipressin

Terlipressin Alone Versus the Standard Therapy With Catecholamines for Hepatic Patients With Septic Shock- Prospective Single Center Randomized Controlled Study.

Start date: July 1, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to evaluate the use of terlipressin compared to standard regimen in hepatic patients with septic shock. Another aim is to compare the mortality rate & the effects on renal functions in both groups.

NCT ID: NCT03606707 Recruiting - Sleep Disturbance Clinical Trials

Efficacy of Fluoroscopic Guided Atlantoaxial Joint Injection on Head and Neck Pain and Sleep Quality in RA Patients

Start date: June 1, 2018
Phase: Early Phase 1
Study type: Interventional

Efficacy of intra-articular steroid injection for inflamed atlantoaxial joint in patients with rheumatoid arthritis Inclusion criteria Patients with rheumatoid arthritis with MRI findings of atlantoaxial joint inflammation and failure of resolution after 2 weeks systemic steroid administration Exclusion criteria Coagulopathy, allergy to contrast material, pregnancy Interventional group (AS) group, received intra-articular steroid injection for atlantoaxial joint. , in addition to methotrexate and chloroquine 400 mg per day.

NCT ID: NCT03605823 Recruiting - Glaucoma Secondary Clinical Trials

Pars Plana Ex-Press Shunt in Vitrectomized Eyes

Start date: November 1, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

Implantation of Ex-Press Minishunt via the pars plana in treatment of secondary glaucoma in vitrectomized eyes achieves promising results avoiding complications of other surgical modalities.

NCT ID: NCT03605186 Recruiting - Clinical trials for Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy

Prevention of Oral Mucositis After Using Chamomile Oral Cryotherapy Versus Oral Cryotherapy in Pediatric Cancer Patients Receiving Chemotherapy.

Start date: February 2019
Phase: N/A
Study type: Interventional

oral mucositis is a painful situation that significantly affects patients' quality of life with the severe cases being associated with ulcerated mucosa and secondary infection which may lead to life-threatening sepsis.Chamomile infusion in cryotherapy was used to aid in reduction of chemotherapy induced mucositis and to enhance the effect of standard cryotherapy alone by its anti-inflammatory, antifungal and antibacterial effect. The occurrence of oral mucositis is a significant complication of chemotherapy with prevalence of up to 80% in pediatric patients.The study is to be conducted at the in and outpatient clinics at the Department of Pediatric Oncology, National Cancer Institute,Egypt. A Structured interview questionnaire sheet will be filled with personal, medical and dental history. Intraoral examination will be carried out using sterile latex gloves, masks, plain mouth mirrors, sterile gauze and wooden tongue depressor. Patients who will agree to participate in the study will watch a video explaining how to perform oral hygiene.Preparation of the interventions is done in the clinic with 400 ml of distilled water with or without the infusion of 10 g of chamomile flowers."Chamomile classic infusion, Royal Herbs" .Ice cubes will be prepared in special ice trays placed in the chemotherapy center for this purpose.Patients will be instructed to swish the ice cubes around their oral cavities starting 5 minutes before chemotherapy infusion, continuing 30 minutes throughout the session and for additional 35 minutes after completion of intravenous chemotherapy session. Follow ups are done at the 8th,15th and the 21st day of interventions application.

NCT ID: NCT03604913 Recruiting - Clinical trials for Aortic Root Aneurysm

Aortic Valve Sparing Root Replacement Versus Bentall

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

This study was designed to evaluate the hypothesis that the operative and midterm results of valve-sparing aortic root replacement are equivalent to those of the Bentall. Objective 1: Evaluate short-term (one-to-six months) and mid-term (six-to-forty-eight months) results of aortic valve-sparing procedures. Objective 2: Compare the results of aortic valve-sparing procedures with the group of patients undergoing Bentall procedures during the same period. Objective 3: Assess outcomes of both procedures through evaluation of postoperative: A) primary outcome measures: 1. Intraoperative or intrahospital death. 2. Reexploration for bleeding. 3. Reoperation rate. 4. Grade of aortic valve regurgitation (0-4). B)secondary outcome measures: 1. Grade of aortic valve regurgitation (0-4). 2. Mean gradient on the aortic valve(mmHg). 3. Thromboembolism / bleeding. 4. Prosthetic/native valve endocarditis. 5. 2-year mortality

NCT ID: NCT03603418 Recruiting - Clinical trials for Dexamethasone Effect on Induction of Labor

Role Of Dexamethasone In Induction Of Labor

Start date: July 13, 2018
Phase: Phase 4
Study type: Interventional

Research hypothesis : In pregnant women undergoing induction of labor, intramuscular injection of dexamethasone may accelerate induction delivery interval. Research question : In pregnant women undergoing induction of labor, does intramuscular injection of dexamethasone accelerate induction delivery interval ? This study aims to assess the effect of intramuscular administration of dexamethasone on the induction delivery interval in full term patients undergoing induction of labor.

NCT ID: NCT03599700 Recruiting - Thrombosis Clinical Trials

Risk Factors and Predictors of Thrombosis in Myeloprolferative Neoplasms

Start date: December 20, 2019
Phase:
Study type: Observational [Patient Registry]

To assess the clinical risk factors and predictable biomarkers of thrombotic complications in cases of philadelphia negative myeloproliferative disorders.

NCT ID: NCT03590964 Recruiting - Clinical trials for Atrophied Posterior Maxilla

One-stage Maxillary Sinus Elevation Using a Bone Core Containing an Implant From the Mandibular Symphysis

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

Two groups of patients with atrophy in posterior maxilla indicated for sinus lift. First group will be subjected to open sinus lift with chin bone graft. Second group will be subjected to sinus floor elevation using a bone ring.

NCT ID: NCT03586713 Recruiting - Caries, Dental Clinical Trials

Accuracy Of Sopro-Life Camera In Comparison With ICDAS II For Detection Of Initial Caries

Start date: May 2019
Phase: N/A
Study type: Interventional

This study will be conducted to assess diagnostic predictive values of a light induced fluorescence intraoral camera versus those of the visual-tactile assessment method according to modified ICDAS-II criteria in clinical

NCT ID: NCT03583164 Recruiting - Clinical trials for Invasive Fungal Infections

Evaluate F901318 Treatment of Invasive Fungal Infections in Patients Lacking Treatment Options

FORMULA-OLS
Start date: June 6, 2018
Phase: Phase 2
Study type: Interventional

A study to evaluate F901318 (study drug) for the treatment of invasive fungal infections in patients lacking suitable alternative treatment options.