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NCT ID: NCT04441073 Recruiting - Pressor Response Clinical Trials

Lignocaine Nebulization for Attenuation of Intubation Stress Response

Start date: February 24, 2021
Phase: Phase 4
Study type: Interventional

To study the effect of lignocaine nebulization on attenuation of the pressor response during induction and emergence of anesthesia in patients with severe pre-eclampsia

NCT ID: NCT04438798 Recruiting - Maternal Death Clinical Trials

High Flow Nasal Cannula to Prevent Deoxygenation During Induction of General Anesthesia in Cesarean Section

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) using high flow oxygen therapy for preoxygenation and oxygen supplementation during apnoea has shown promising results

NCT ID: NCT04438694 Recruiting - COVID19 Clinical Trials

Assessment of the Effect of Convalescent Plasma Therapy in Patients With Life-threatening COVID19 Infection

CP IN COVID19
Start date: June 1, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

- This clinical trial proposal is based on the FDA protocol for emergency use of convalescent plasma for treatment of COVID-19 cases, and on the WHO guidelines for use of convalescent plasma in other infectious diseases. - This Clinical trial is to be applied in Cairo University quarantine hospital. The collection, testing and storage of convalescent plasma will be done inside CUH main blood bank. The concept of this clinical trial is built on the collection of convalescent plasma from individuals who had recovered from documented infection with SARS-CoV-2, to be used for patients with- or at high risk of progression to- severe/life-threatening clinical conditions due to SARS-CoV-2 infection. An informed consent is required to join this clinical trial; patients will be transfused with one or two units of ABO compatible convalescent plasma. Those patients will be followed up and the clinical and laboratory data will be compiled, including adverse events related to the administration of convalescent plasma (CP). Other data to be collected retrospectively will include patient demographics, acute care facility resource utilization (total length of stay, days in ICU, days intubated, and survival till discharge from an acute care facility).

NCT ID: NCT04436445 Recruiting - Chronic Pelvic Pain Clinical Trials

Effect of Neurogenic Acupoint CUPPING ON WOMEN WITH CHRONIC PELVIC PAIN

Start date: July 15, 2018
Phase: N/A
Study type: Interventional

PURPOSE: The purpose of this study is to determine the effect of dry cupping on women with chronic pelvic pain. BACKGROUND: Recent studies have examined the efficacy of dry cupping on acupoints for various pain-related conditions. They showed good result . However, no studies up to date has been evaluated the effect of dry cupping in treating Chronic pelvic pain. Therefore, this study is the first one which aims to investigate the effect of dry cupping on women suffering from Chronic pelvic pain. This study may expand the role of physiotherapy in woman's health. HYPOTHESE: There is no effect of bioptron light therapy on postmenopausal osteoporosis. RESEARCH QUESTION: There is no effect of dry cupping on chronic pelvic pain.

NCT ID: NCT04434677 Recruiting - Breast Cancer Clinical Trials

Hypofractionation And Ultra-Hypofractionation In Adjuvant Radiotherapy For Breast Cancer

Start date: June 28, 2019
Phase: N/A
Study type: Interventional

Prospective randomized study comparing 5 fractions in alternative days to standard 15 fractions regarding effectiveness and feasibility during adjuvant treatment in breast caner patients aged above 50 years

NCT ID: NCT04434014 Recruiting - Diet, Healthy Clinical Trials

Proper Nutrition And Its Relation To Oral Diseases In Covid -19 Era

Start date: June 8, 2020
Phase:
Study type: Observational

effect of proper diet and vitamins on the oral health and the regeneration of the taste and smell in Covid 19 patients

NCT ID: NCT04433624 Recruiting - Postoperative Pain Clinical Trials

Analgesic Efficacy of the Erector Spinae Plane Block Using Bupivacaine Versus Bupivacaine/Magnesium Sulphate in Patients Undergoing Lumbar Spine Surgery

Start date: July 18, 2020
Phase: N/A
Study type: Interventional

Introduction: Severe postoperative pain following spine surgery is a significant cause of morbidity, extended length of facility stay, and marked opioid usage The analgesic regime for postoperative pain usually includes paracetamol,NSAIDs and opioids. The opioid epidemic as well as the opioid side effects2 (sedation,respiratory depression, constipation, delayed patient mobilization) has led perioperative physicians to find a way of decreasing the use of opioids. Increasing the use of regional anesthesia is one of the measures to this end. Ultrasound-guided erector spinae plane block (ESP) is a-- popular, interfascial regional technique that was initially described for the management of thoracic neuropathic pain . As the erector spinae fascia extends from the nuchal fascia cranially to the sacrum caudally, local anesthetic agents extend through several levels, and the block can be effective over a large area The ESP block provides effective postoperative analgesic effect for 24 hours in patients undergoing lumbar spinal surgery Magnesium sulfate (MGS) is a noncompetitive antagonist of N-methyl, D-aspartate (NMDA) receptors with an analgesic effect and is essential for release of acetylcholine from the presynaptic terminals and, similar to calcium channel blockers (CCB), can prevent the entry of calcium into the cell It is suggested that magnesium has many important roles to play in nociception

NCT ID: NCT04431505 Recruiting - Apoptosis Clinical Trials

Anaesthesia and Apoptosis

Start date: June 12, 2020
Phase:
Study type: Observational

Anesthetics cause widespread apoptosis in the developing brain, resulting in neurocognitive abnormalities. However, it is unknown whether anesthesia-induced neurotoxicity occurs in humans because there is currently no modality to assess for neuronal apoptosis in vivo

NCT ID: NCT04431492 Recruiting - Clinical trials for Effect of Anaesthesia on Basic Aminoacids

Effect of Anaesthesia on Basic Aminoacids

Start date: June 11, 2020
Phase:
Study type: Observational

Basic amino acids are acids that contains amino groups more than carboxylic groups. At least five basic amino acids namely; Arginine, citrulline, ornithine, lysine and hydroxylysine metabolize in our body. Loss of body protein represents a typical feature of the catabolic response to surgery.

NCT ID: NCT04431232 Recruiting - Obesity Clinical Trials

Endo-Band: Endoscopic Band Ligation for Weight Loss

Start date: February 1, 2020
Phase: N/A
Study type: Interventional

To the best of our knowledge, this is the first study to use endoscopic band ligation for weight loss. All ligatures will be performed in the gastric body starting at the distal body; 5 parallel rows, with the last one in the proximal body.The entire procedure can be completed in 30 min. Oxygen is used for endoscopic air insufflation.Endoscopy is performed using propofol for sedation.