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NCT ID: NCT04929509 Recruiting - White Spot Lesion Clinical Trials

P11-4 and Nanosilver Fluoride Varnish in Treatment of White Spot Carious Lesions

Start date: December 5, 2020
Phase: N/A
Study type: Interventional

Background: Great efforts have been undertaken for dental caries prevention. Among the recent remineralizing materials, Nano silver fluoride varnish products which are based on nanotechnology have been proposed for "repairing" enamel . Regenerative medicine-based approaches for caries treatment focus on biomimetic remineralization of initial carious lesions as a minimal invasive therapy using Self-Assembling Peptide P11-4 (Curodont Repair) which enhances remineralization of white spot lesions. Purpose of the Study: The aim of this study is to compare clinically and microbiologically the therapeutic effect of Self Assembling Peptide P11-4 (Curodont Repair), nano silver fluoride varnish and 5% fluoride varnish (Duraflor) on remineralization of enamel White Spot Lesions in permanent teeth of adults.

NCT ID: NCT04928768 Recruiting - Clinical trials for Patient Satisfaction

Factors Influencing Patient Satisfaction in an Egyptian Sample After Orthodontic Treatment of Different Malocclusions

Start date: November 1, 2020
Phase:
Study type: Observational

Previously, patient satisfaction with orthodontic treatment has been reported at a broad range of 34% to 95% but these values mostly represent satisfaction for tooth alignment or simple satisfaction with treatment results. In keeping with the increased focus on patient satisfaction, many other factors were put into consideration in our study which contributes to the level of total satisfaction as host factors, concerns regarding the treatment, treatment motivation and discomfort during or after treatment. There are also a lack of studies conducted for orthodontic treatment satisfaction using previously validated questionnaires as well as correlation between patient's treatment satisfaction and ABO grading hasn't been sufficiently discussed in the literature, this study aims to address that gap. It would be also beneficial to investigate the frequency of different malocclusions presented in a sample of postorthodontic patients as it will give an insight about the distribution of the different malocclusion treated within the clinic and the degree of success in treating such malocclusions.

NCT ID: NCT04928404 Recruiting - Clinical trials for Obstructive Sleep Apnea

Barbed Suspension of the Tongue Base for Treatment of Obstructive Sleep Apnea Patients

Start date: June 12, 2021
Phase: N/A
Study type: Interventional

Obstructive sleep apnea syndrome (OSAS) is a common clinical condition in which the throat narrows or collapses repeatedly during sleep, causing obstructive sleep apnea events. One of the most common sites for collapse during sleep is hypo-pharyngeal space. It was founded in 50% of OSA patients those have moderate and severe apnea. DeRowe et al invented the Tongue base suspension operation in 1998 for sleep disordered breathing.

NCT ID: NCT04928391 Recruiting - Cleft Palate Clinical Trials

A Single Bolus of Dexmedetomidine Versus Nalbuphine in Postoperative Agitation

Start date: June 20, 2021
Phase: Phase 3
Study type: Interventional

The hypothesis of this study is to investigate and compare the efficacy between the administrations of single intravenous (IV) dose of dexmedetomidine versus nalbuphine in preventing immediate postoperative agitation in children undergoing cleft palate repair.

NCT ID: NCT04928352 Recruiting - Cleft Palate Clinical Trials

Nebulized Bupivacaine Analgesia for Cleft Palate Repair

Start date: June 14, 2021
Phase: Phase 3
Study type: Interventional

In this study we introduce a potent local anesthetic; bupivacaine 0.5% in two different doses by nebulization as a preemptive analgesia to compare efficacy and safety in children with cleft palate repair.

NCT ID: NCT04928300 Recruiting - Rib Fractures Clinical Trials

Low Dose Dexmedetomidine Versus Ketamine in Multiple Fracture Ribs

Start date: June 12, 2021
Phase: Phase 3
Study type: Interventional

In our study, we assess the diaphragmatic function, pain quality and anti-inflammatory properties between low dose infusion of dexmedetomidine and ketamine in patients with multiple fracture ribs on conservative treatment.

NCT ID: NCT04927715 Recruiting - Clinical trials for Peripartum Cardiomyopathy

Irisin Expression and Gene Polymorphism With Peripartum Cardiomyopathy.

Start date: February 20, 2021
Phase:
Study type: Observational

this is an observertional study aimed at Study the association between the level of irisin expression and (Fibronectin Type III Domain Containing 5 (FDNC5) gene polymorphism in female patients with peripartum cardiomyopathy.

NCT ID: NCT04926454 Recruiting - Pain, Postoperative Clinical Trials

Efficacy of Adding Dexmedetomidine as an Adjuvant to Bupivacaine in TAP Block and Caudal Block

Start date: September 22, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

This study compares the efficacy of Dexmedetomidine as an adjuvant to Bupivacaine in Ultrasound Guided Transversus Abdominis Plane Block versus Caudal Block for post-operative analgesia in children undergoing congenital inguinal hernia repair especially to provide prolonged post-operative analgesia and decrease opioid consumption.

NCT ID: NCT04923737 Recruiting - Clinical trials for Major Abdominal Surgery

Immunomodulatory Effects of Dexmedetomidine Infusion

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

Anesthetic management may affect both immunostimulatory and immunosuppressive mechanisms directly by modulating immune cell function or indirectly by attenuating the stress response, Thus, the choice of anesthetic technique may affect clinical outcomes by perturbing the balance between pro- and anti-inflammatory responses,anesthetics favoring this delicate balance are thus desirable as their use may reduce postoperative complications and mortality

NCT ID: NCT04921709 Recruiting - Clinical trials for Irritable Bowel Syndrome

Renal Involvement in Inflammatory Bowel Disease Patients

Start date: June 1, 2021
Phase:
Study type: Observational

To evaluate renal involvement in inflammatory bowel disease patients .