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NCT ID: NCT05556330 Recruiting - Clinical trials for Computer Guided Alveolar Bone Augmentaion

Computer Guided Versus Free Hand Horizontal Ridge Augmentation in Anterior Mandible.

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

Assessment of horizontal ridge augmentation in anterior mandible using computer guided autogenous cortical shell technique versus free hand technique: randomized clinical trial

NCT ID: NCT05556317 Recruiting - Clinical trials for Sleep Disturbances and Insomnia

Effect of Resistive Exercise on Insomnia in Post Menopausal Women

Start date: September 30, 2022
Phase: N/A
Study type: Interventional

the aim of this study is to investigate the efficacy of resistive exercise on insomnia in post menopausal women

NCT ID: NCT05556005 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

Efficacy of Trimetazidine in Diabetic Patients

Start date: September 18, 2022
Phase: Phase 2
Study type: Interventional

Subclinical diastolic dysfunction represents the early phase of diabetic cardiomyopathy and is a common complication among type 2 diabetic patients that increases mortality rate among those patients and can progress to heart failure with preserved ejection fraction. Trimetazidine is an anti-ischemic agent widely used in the treatment of coronary artery disease and it has positive effects on energy metabolism in heart failure. Therefore, we hypothesized that trimetazidine may have potential benefit on the amelioration of the inflammatory insult and improving the clinical outcomes in patients with diabetic cardiomyopathy especially if applied in the early stages.

NCT ID: NCT05555511 Recruiting - Clinical trials for Kidney Injury, Acute

Perioperative Use of NAC to Prevent AKI in Patients With Pre-existing Moderate Renal Insufficiency Following Cardiac Surgery

Start date: August 26, 2022
Phase: N/A
Study type: Interventional

Acute kidney injury (AKI) or renal impairment is an established complication of cardiac surgery occurring with an incidence up to 30%, To date, no agent has conferred renal protection. Considerable interest has developed in the potential for Nacetylcysteine (NAC) to exert a renoprotective effect in patients undergoing cardiac surgery. Due to the beneficial effect of NAC on contrast nephropathy and its reported anti-inflammatory effects.

NCT ID: NCT05553704 Recruiting - Clinical trials for Inflammatory Bowel Diseases

Metformin in Patients With Ulcerative Colitis Treated With Mesalamine

Start date: November 1, 2022
Phase: Phase 2
Study type: Interventional

Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease characterized by diffused inflammation of the colon and rectum mucosa, however, the exact underlying mechanisms of UC remain poorly understood.UC is strongly dependent on cellular immune reaction and exaggerated inflammatory response due to genetic, immune and environmental factors.

NCT ID: NCT05553561 Recruiting - Dry Eye Disease Clinical Trials

Intense Regulated Pulse Light Therapy in Dry Eye Disease

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to assess the effect of intense regulated pulse light (IRPL) on the treatment of Dry eye.

NCT ID: NCT05553509 Recruiting - Clinical trials for Chronic Limb Threatening Ischemia

Clinical Outcomes Following Surgical Debridement of Diabetic Foot Infection With Borderline Vascularity

Start date: January 1, 2023
Phase:
Study type: Observational

Observe Timing to complete healing of wounds & Limb salvage in both cohorts those who are undergoing Debridement only and those who are undergoing Debridement plus PTA

NCT ID: NCT05553483 Recruiting - Allergic Rhinitis Clinical Trials

Effect of Laser Acupuncture Alone or Combined With Pranayama Exercise on Inflammation in Allergic Rhinitis

Start date: September 15, 2021
Phase: N/A
Study type: Interventional

Allergic rhinitis (AR) represents one of the most common global health problems with seriously increasing incidence over the last decades.The goal of the treatment of rhinitis is to prevent or reduce the symptoms through reduction of the inflammation of affected tissues. Acupuncture and pranayama yoga exercises had reported a significant improvement in daily symptoms and an increase of symptom-free days in many studies enrolling patients.

NCT ID: NCT05548478 Recruiting - Myopia Clinical Trials

Corneal Endothelial Cell Injury Induced by Mitomycin-C

Start date: September 2022
Phase: N/A
Study type: Interventional

our study will investigate the effecacy of Mitomycin-C in TransEpi single step photorefractive keratectomy (PRK) and alcohol assisted PRK

NCT ID: NCT05546762 Recruiting - Empyema, Pleural Clinical Trials

Trial of Antiseptic Irrigation for Pleural Infection

RINSE
Start date: September 19, 2022
Phase: Phase 2
Study type: Interventional

Pleural antiseptic irrigation (PAI) is used in conjunction with open drainage for treating adults with chronic post-thoracotomy empyema. The antiseptic povidone-iodine can safely be instilled into the pleural cavity for the purpose of pleurodesis and has recently been described for pleural irrigation in the acute management of paediatric pleural infection with good outcomes. A recent case report demonstrated the safe use of povidone-iodine pleural irrigation in a patient with complex pleural empyema with successful medical management. In a previous pilot study, antiseptic irrigation led to less referral to surgery and shorter length of hospital stay in comparison to no irrigation. This study aims to investigate the effect of antiseptic pleural irrigation (using povidone iodine) on the inflammatory response in adults patients with pleural infection in comparison to irrigation with normal saline alone. A reduction in the systemic inflammatory response can be inferred to correlate with reduction in the infection burden in the pleural space.